Alternative Splicings

MicroRNAs GnRH and the failure of sex research

Summary: “The Bull Sperm MicroRNAome and the Effect of Fescue Toxicosis on Sperm MicroRNA Expression” accurately represents what is known about food energy-dependent RNA-mediated cell type differentiation in species from soil microbes to humans. MicroRNAs are not new players in the hypothalamic control of fertility and the effects of food odors and pheromones on microRNAs MicroRNAs GnRH and the failure of sex research

Food energy-dependent cell type differentiation (3)

Food energy-dependent cell type differentiation (2) Summary: Until The Scientist provides the rest of the story, see our section on molecular epigenetics in: From Fertilization to Adult Sexual Behavior (1996) and this refutation of neo-Darwinian pseudoscientific nonsense Nutrient-dependent/pheromone-controlled adaptive evolution: a model Micronutrients, Macro Impact …the work was related to human research conducted later by Food energy-dependent cell type differentiation (3)

Food energy-dependent cell type differentiation (2)

Summary: The concept of “faster-evolving DNA” regions in the context of nucleotide variation in both the 16S and 12S sequences is not consistent with any accurate representation of how the functional structure of supercoiled DNA must be linked from energy-dependent changes in angstroms to ecosystems in all living genera. Conserved molecular mechanisms link the sense Food energy-dependent cell type differentiation (2)

Food energy-dependent epigenetic adaptation (2)

Due to the overwhelming support for my model of top-down causation and all energy-dependent biophysically constrained biodiversity on Earth, I will replace Food energy-dependent epigenetic adaptation (2) with the more appropriately titled God’s shrinking role in your salvation See: Food energy-dependent epigenetic adaptation and God’s shrinking role in your salvation (in prep) before proceeding to Food energy-dependent epigenetic adaptation (2)

Energy-dependent epigenetic translation to mRNA stability (5)

Energy-dependent epigenetic translation to mRNA stability (4) From Fertilization to Adult Sexual Behavior Small intranuclear proteins also participate in generating alternative splicing techniques of pre-mRNA and, by this mechanism, contribute to sexual differentiation in at least two species, Drosophila melanogaster and Caenorhabditis elegans…. See also: The Supraspliceosome – A Multi-Task Machine for Regulated Pre-mRNA Processing Energy-dependent epigenetic translation to mRNA stability (5)

Eliminating energy from light induced changes in complex systems

Researchers identify key regulator of fetal growth in mice The study is one of the first to show that KRAB-zinc finger proteins, which are well-known for silencing viral genes left over from ancient infections, can also play an essential role in fetal and placental development. See also: Divergent prebiotic synthesis of pyrimidine and 8-oxo-purine ribonucleotides Eliminating energy from light induced changes in complex systems

Cytosis in the light of evolution

In the Light of Evolution Excerpt 1 (with my emphasis) Evolutionary Biology bring together a collection of articles exploring how evolutionary principles applied across the spectrum of biology can shed light on a diverse range of topics from molecules to ecosystems, and with a particular emphasis on human genetics, interactions with the environment, and health Cytosis in the light of evolution

UV light and non-coding RNA

UV Irradiation Induces a Non-coding RNA that Functionally Opposes the Protein Encoded by the Same Gene …these events underlie a switch to expression of short mRNA isoforms and preferential use of alternative last exons in a number of genes, including ASCC3. Intriguingly, the switch between ASCC3 isoforms occurs on more than one level, in that the UV light and non-coding RNA