Autophagy

Information Wars started by medical practitioners (1)

Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems (Apr 11, 2018) My Summary: The pheromone-controlled physiology of reproduction biophysically constrains viral latency and the transgenerational epigenetic inheritance of healthy longevity in the context of fixation of the EDAR V370A variant. The variant links changes in a single base pair to differences in an amino acid substitution, which links the mouse-to-human model of ecological adaption from microbes to all extant morphological and behavioral biodiversity. See for comparison: Biological Networks: An Introductory…

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Natural models inspire future therapeutics (2)

Summary: Food odors and pheromones biophysically constrain viral latency, and an effective treatment for all neurodegenerative diseases was proposed in this 2011 patent application “Pheromones and the luteinizing hormone for inducing proliferation of neural stem cells and neurogenesis“ See for comparison: Identification of miR-379/miR-656 (C14MC) cluster downregulation and associated epigenetic and transcription regulatory mechanism in oligodendrogliomas. The post- transcriptionally regulatory network of this cluster showed enrichment of key cancer-related biological processes such as cell adhesion and migration. Also, there was…

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NHEJ disruption and HDR correction?

International Workshop “Targeting RNA world” Dear colleagues! Scientists of the Institute of Chemical Biology and Fundamental Medicine SB RAS cordially invites you to attend International Workshop “Targeting RNA world” in the frame of the project of Russian Scientific Foundation “New generation of RNA-targeting oligonucleotide derivatives as a platform for designing innovative therapeutics” (no. 14-44-00068). Workshop is being held in Park Inn by Radisson Pulkovskaya Hotel & Conference Centre St Petersburg, Saint-Petersburg, Russia, September 2-7 2018. We will discuss all aspects…

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Virus-driven genome engineering causes cancer?

CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response Inhibition of p53 prevents the damage response and increases the rate of homologous recombination… In the 1990’s, Abcam researchers discovered the cell death gene. Now see: Mechanisms of Recombination conference See also: P53 toxicity is a hurdle to CRISPR/CAS9 screening and engineering in human pluripotent stem cells We demonstrated the toxic response is tp53-dependent and the toxic effect of tp53 severely reduces the efficiency of precise genome-engineering in hPSCs. Reported as:…

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The concept of a species (4)

Trump Tries to Destroy the West The alliance between the United States and Western Europe has accomplished great things. It won two world wars in the first half of the 20th century. Then it expanded to include its former enemies and went on to win the Cold War, help spread democracy and build the highest living standards the world has ever known. President Trump is trying to destroy that alliance. —– Scientific creationists from South Korea, the “creationist capitol of…

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An evolutionary theory killer

The concept of a species (3)

Gene expression evidence for remodeling of lateral hypothalamic circuitry in cocaine addiction (2005) This remodeling of LH circuitry could contribute to the chronic deficit in reward function that has been hypothesized to drive the transition to drug addiction. Lena D. van der Stap discussed her role in the publication of this article, which failed to make any assumptions about mutations and/or evolution. James Kohl Did you co-author Gene expression evidence for remodeling of lateral hypothalamic circuitry in cocaine addiction McEwen told…

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Misleading evidence, Raman Hyperspectroscopy and FB jail

Yesterday, on the topic of vaccines used to prevent Ebola virus transmission, I wrote: …. There is no such thing as an extinct virus. Their ability to steal energy is biophysically constrained until nutrient stress and/or social stress cause their reactivation. I provided a link to The Darwin Code Today, I read about The misleading evidence that fooled scientists for decades After posting this comment to “The Conversation,” I learned I was blocked from posting anything to Facebook. Have you considered…

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Biologically uninformed science idiot: Self-defense (4)

R. P. Feynman: Elementary Particles and the Laws of Physics (1986 Dirac memorial lecture) I Snippet: “The problem would be pushed back to Creation and God knows how that was done.” It has since become apparent to all serious scientists that God understands the transfer of photosynthetic energy. He linked the creation and transfer of energy across the quantum to classical border. Many biologically uninformed science idiots probably still think the border exists in the context of the problem of…

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An evolutionary theory killer

Biologically uninformed science idiot: Self-defense (3)

Summary: No ecosystems exist at any level of examination outside the context of the anti-entropic virucidal energy of light-activated endogenous substrates in all cell types of all living genera. The quantized energy-dependent creation of nucleotides links the creation of sunlight to fixation of energy in every organism on Earth.  Fixation of the energy is microRNA-mediated. The energy-dependent creation of microRNAs has been linked to healthy longevity via direct effects on organized genomes. For example, microRNAs typically biophysically constrain viral latency.…

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From quantum physics to quantum souls (4)

The long-range consequences of food energy-dependent social factors predictably link everything known about social odors called pheromones from the quantized energy in food to metabolism and biophysically constrained viral latency.  Sympatric speciation exemplifies what is known about how quantized energy links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency in species from microbes to humans. In this review of biophysically constrained viral latency and biodiversity, I linked energy-dependent changes from angstroms to ecosystems in the mouse-to-human model of microRNA-mediated amino…

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  • Randomness and Divine Providence
    A Q&A on randomness and God’s providence …the main goal is to really put together a collection of scholarly studies of these issues: physicists, biologists, […]
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