Autophagy

Light-activated PTEN-dependent viral latency (2)

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See first: Light-activated PTEN-dependent viral latency (1) 12/25/19 On 12/26/19, Cold Spring Harbor Laboratory responded to my accurate representations of light-activated energy-dependent biophysically constrained viral latency with a report on Biophysical models of cis-regulation as interpretable neural networks 11/8/19 See: Finally, machine learning interprets gene regulation clearly 12/26/19 “…understanding how something like gene regulation works—is … Light-activated PTEN-dependent viral latency (2)

Light-activated PTEN-dependent viral latency (1)

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See: Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation” (1964) The synthesis of RNA in isolated thymus nuclei is ATP dependent. The energy required for biophysically constrained oxidative phosphorylation, viral latency, and cell type differentiation comes from food. Amusing anecdote (for polymaths): See: PTEN … Light-activated PTEN-dependent viral latency (1)

An exciting first step? (1)

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Herpes’ Achilles’ Heel  (12/11/19 ) …an exciting first step…suggests it is possible to permanently silence lifelong infections… The energy from food and the pheromone-controlled physiology of reproduction silences lifelong infections in species from microbes to humans. If it did not, there would be no such thing as permanently silenced human endogenous retroviruses, such as the … An exciting first step? (1)

mRNA Structure and Function (2)

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A fail-safe system to prevent oncogenesis by senescence is targeted by SV40 small T antigen 12/9/19 HP1BP3 is part of a fail-safe system to prevent virus-driven oncogenesis. It positively regulates light-activated global biogeochemical cycles of microRNA biogenesis, and thereby is essential for prevention of the senescence-associated secretory phenotype. The light-activated energy-dependent assembly of the microRNA-RNA-peptide … mRNA Structure and Function (2)

The tipping point (revisited): 95K (5)

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Thanks to the overwhelming ignorance of biologically uniformed and terrified theorists, today’s number of my 28-day profile visits is reduced 63.3% and mentions are reduced 63.4%. Theorists seem to hate me: See why: Stable suppression of gene expression by short interfering RNAs targeted to promoter in a mouse embryonal carcinoma stem cell line 9/25/10 Yesterday, … The tipping point (revisited): 95K (5)

mRNA Structure and Function (1)

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See also: THE WORLD’S LARGEST MEETING TO ACCELERATE OLIGONUCLEOTIDE AND PEPTIDE PRODUCTS FROM EARLY DISCOVERY TO LATE-STAGE DEVELOPMENT & COMMERCIALIZATION May 11-20, 2020 The light-activated assembly of the microRNA-RNA-peptide nanocomplex is being commercialized and biologically uninformed theorists missed it. How stupid is that? For other information on what the theorists missed, see: Codon identity regulates … mRNA Structure and Function (1)

The tipping point (revisited): 95K (4)

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Carbohydrate Metabolism Regulated by Antisense vicR RNA in Cariogenicity 12/10/19 These findings have a number of implications and have reshaped our understanding of bacterial gene regulation from its transcriptional conception to the key roles of regulatory RNAs. The energy-dependent Creation of regulatory RNAs links the Creation of sunlight and water to all oxygen-dependent ecological adaptations … The tipping point (revisited): 95K (4)

Ignoring effects of microRNAs on Twitter (1)

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Summary: Those who fail to link food energy to biophysically constrained human endogenous retroviruses via the physiology of pheromone-controlled reproduction in pigs will suffer unnecessarily and die prematurely from the virus-driven degradation of their messenger RNA. Indeed, the biologically uninformed pigs will continue to be led to their slaughter by those who use the Harvard … Ignoring effects of microRNAs on Twitter (1)

The tipping point (revisited): 95K (2)

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RE: A Harvard geneticist’s goal: to protect humans from viruses, genetic diseases, and aging 12/8/19 If pseudoscientists, libtards, and Democrats were scared to comment before, they may be scared to death by the claims George Church, and the interviewer, made yesterday for comparison to the claims in George Church refutes theistic evolution 2/9/17 Who made … The tipping point (revisited): 95K (2)

Biological Function of Autophagy (2)

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“How often do we still hear that quantum effects can have little relevance in the study of biology, or even that we eat food in order to gain energy?” (Roger Penrose 8 August 1991) Moving forward: Autophagy and Energy Metabolism …we review the correlations between autophagy and energy homeostasis in terms of oxidative phosphorylation, reactive … Biological Function of Autophagy (2)