base editing

The eternal significance of microRNAs and the Vietnam Memorial (2)

June 1, 2018
James Kohl
Adaptations, Alternative Splicings, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Physics, RNA Directed, RNA interference, Subatomic
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Summary: Quantized energy as information has been linked from what organisms eat to biophysically constrained membrane protein construction in the context of viral latency and healthy longevity. Cryoelectron microscopy (aka electron cryomicroscopy for obfuscation) clearly links what is known about the virus-driven degradation of messenger RNA to all pathology or from energy-dependent RNA-mediated DNA repair to species survival. Membrane Proteins – Richard Henderson May 31, 2018 Energy as information and biophysically constrained membrane protein construction – James Kohl Feb 15,…

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From quantum physics to quantum souls (4)

May 30, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations
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The long-range consequences of food energy-dependent social factors predictably link everything known about social odors called pheromones from the quantized energy in food to metabolism and biophysically constrained viral latency.  Sympatric speciation exemplifies what is known about how quantized energy links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency in species from microbes to humans. In this review of biophysically constrained viral latency and biodiversity, I linked energy-dependent changes from angstroms to ecosystems in the mouse-to-human model of microRNA-mediated amino…

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From quantum physics to quantum souls (3)

May 29, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic
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Conclusion: The quantized energy-dependent creation of microRNAs links the anti-entropic virucidal energy of sunlight to food energy-dependent pheromone-controlled differences in all morphological and behavioral diversity via sympatric speciation. Food odors and pheromones biophysically constrain viral latency. VoteVets.org …a VoteVets.org spokesman told The Washington Post that the group had 20,000 members, including 1,000 veterans of the wars in Iraq and Afghanistan’.[6] According to the group’s website, the group has over 220,000 supporters.[7] See for comparison: Veterans Group Blasts Trump’s Memorial Day…

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From quantum physics to quantum souls

May 27, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic
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Search for the term they use: quantized energy in the context of quantized energy levels. You will find few sources other than those I have placed into the context of the National Microbiome Initiative and Precision Medicine Initiative in this virtual conference presentation from 2017. Energy as information and constrained endogenous RNA interference (video) Published on Feb 15, 2017 Feedback loops link quantized energy as information to biophysically constrained RNA-mediated protein folding chemistry. Light induced energy-dependent changes link angstroms to…

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An evolutionary theory killer

Epigenetic inheritance of spatiotemporal regulation (5)

May 25, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations
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Thanks for the Stress, Dad As embryos, the researchers found that the mouse offspring, which exhibited more anxious behavior than usual, also had lower miRNA levels, as did the sperm of the male offspring upon maturity. The stress-linked degradation of messenger RNA is caused by virus-driven energy theft, which has been linked to all pathology in species from bacteria to humans.  For example: Neutrons identify critical details in bacterial enzyme implicated in gastric cancer Ronning’s team focused on H. pylori’s…

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Epigenetic inheritance of spatiotemporal regulation (3)

May 24, 2018
James Kohl
Adaptations, Alternative Splicings, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, microRNA editing, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA interference, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity, Variations, What's in the News
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Summary: Wen Zhou’s group has linked the creation of anti-entropic virucidal light from the quantized energy-dependent creation of microRNAs to the food energy-dependent neuroendocrine origins of human behavior via the pheromone-controlled physiology of reproduction and fixation of RNA-mediated amino acid substitutions in species from microbes to humans. Simply put, she has linked quantum physics to quantum souls via what is known about biophysically constrained viral latency in the context of the cell biology game Cytosis and the future of biology.…

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Cracks in The Granite Wall (1)

May 17, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, What's in the News
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Researchers in Thailand linked US military service in Thailand during the time of the war in Vietnam from the time of the Korean War to denuclearization of North Korea via energy-dependent changes in the influenza B virus.   From scientific creationists in South Korea: A Single Amino Acid at the Polymerase Acidic Protein Determines the Pathogenicity of Influenza B Viruses   They obviously know how to create a virus that would decimate human populations in North Korea and in other…

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Kohl’s Laws of Biology (codon-optimality revisited)

May 11, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News
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Summary: Kohl’s Laws help to explain what was missing from Darwin’s ‘conditions of life.’ Darwin knew nothing about genetics, which means he knew nothing about the epigenetic effects of food odors or pheromones. Ancient hepatitis B viruses from the Bronze Age to the Medieval period 5/7/18 We provide evidence for the creation of HBV genotype A via recombination, and for a long-term association of modern HBV genotypes with humans, including the discovery of a human genotype that is now extinct.…

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An evolutionary theory killer

ATP and RNA-mediated chromosomal stability

May 9, 2018
James Kohl
Adaptations, Alternative Splicings, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic
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Cytosis, a cell biology game for ages 10+ links ATP to viral latency and the protection of all organized genomes from the virus-driven degradation of messenger RNA that serious scientists have linked to all pathology. It is time for a new measure of cell function: Quantifying Cellular ATP Production Rate…(2018) Adenosine triphosphate (ATP) is the most common high energy intermediate of living organisms. Cells utilize the energy derived from the breakdown of cellular fuels to synthesize ATP from ADP and…

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An evolutionary theory killer

A single base change refutes theistic evolution (2)

May 9, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic
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Announcing publication of a model that links the creation of quantized energy from changes in subatomic particles to biophysically constrained viral latency and sympatric speciation in all living genera. Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems This angstroms to ecosystems model of ecological adaptation links nutrient energy-dependent epigenetic effects on base pairs and amino acid substitutions to pheromone-controlled changes in the microRNA/messenger RNA balance and chromosomal rearrangements via the physiology of reproduction in species from microbes to humans. The…

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