Quantum Darwinism (2)

Nonenzymatic polymerase-like template-directed synthesis of acyclic l-threoninol nucleic acid 2/5/21 Orgel and Szostak introduced an amino group into 2′- and 3′-positions9, which enabled effective RNA copying due to acceleration of the ligation reaction10,11. Reported as: Origins of life could have started with DNA-like XNAs 4/6/21 …shorter L-aTNA fragments came together and linked up with each other on the longer L-aTNA template. Critically, this happened in the presence of a compound, called N-cyanoimidazole, and a metal ion, like manganese, both of…

Read More

Quantum Darwinism (1)

See first: Pheromones protect us from viruses parts 1-10 For a historical perspective on the development of healthy ecosystems, see: Pheromonal Regulation of Genetic Processes: Research on the House Mouse (Mus musculus L.) (1994) and From Fertilization to Adult Sexual Behavior (1996) For links from quantum Darwinism to all energy-dependent biophysically constrained biodiversity, see also: Quantum Criticality at the Origin of Life 3/3/15 The number of proteins grows exponentially with the number n of amino acids… Peptide synthesis at the…

Read More

Pheromones protect us from viruses (9)

It may be a form of insanity that prevents theorists, atheists, and Communists from addressing the facts that have been detailed in the context of: Direct Observation of Protonation State Modulation in SARS-CoV-2 Main Protease upon Inhibitor Binding with Neutron Crystallography 3/23/21 …a class of agents called covalent peptidomimetic inhibitors that work by using strings of unnatural amino acids to bind to specific target proteins. See for instance:  A two-amino acid change in the hemagglutinin of the 1918 influenza virus…

Read More

Pheromones protect us from viruses (8)

See first: Pheromones protect us from viruses (7) Summary: When others link God’s Creation of anti-entropic virucidal light to pH-dependent biophysically constrained viral latency via His Creation of water, which is required for the creation of all oxygen-dependent life on Earth, we will see how God’s Creation of Genotypes in all species once protected them, and us, from the virus-driven degradation of messenger RNA. More than 118,000 indexed published articles mention ‘microRNA.’ It is long past time for theorists to…

Read More

Pheromones protect us from viruses (4)

Have you tried and repeatedly failed to put the pieces of a puzzle together? Did you claim it was impossible for anyone else to do it? To me, that exemplifies atheism. This helps to define atheism. Defining the underlying defect in insulin action in type 2 diabetes 3/17/21 …a broad signalling cascade mediated by changes in phosphorylation, gene expression and vesicular trafficking that result in increased nutrient utilisation and storage, and suppression of catabolic processes. The attempt to define the…

Read More

Pheromones protect us from viruses (3)

Creationists link God’s sunlight-activated generation of energy from ambient humidity and the anaerobic production of magnetite in marine microbes to electron transfer. That is how they link the ATP-dependent Creation of RNA to ammonia detection via fixation of amino acid substitutions in protein nanowires. See: Harnessing Electricity-Producing Bacteria 3/2/21 Simply put: When humans eat, their bodies convert sugars from food into electrons. These electrons transfer to oxygen to produce energy that powers the metabolic processes of the cell. It is…

Read More

Defeating disease and Communism (4)

On 3/16/21, Timothy Normand Miller, in his role as the stupid atheist, @theosib2 wrote: If there were any of the typical indications of a designer in DNA, then I would consider that there must have been a designer. However, none of those can be found. Peptide synthesis at the origin of life 11/13/20 and The Amino Acid Composition of Quadruplex Binding Proteins Reveals a Shared Motif and Predicts New Potential Quadruplex Interactors 9/13/18 were linked to Properties and biological impact…

Read More

Defeating Disease and Communism (1)

Defeating Diseases with Energy 1/9/18 The mitochondria turn food’s hydrogen and carbon and inhaled oxygen into carbon dioxide (CO2), water and adenosine triphosphate, or ATP, which stores energy. God’s ATP-dependent Creation of RNA links protonated RNA interference to healthy longevity. See: Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation” (1964) The synthesis of RNA in isolated thymus nuclei is ATP dependent. For the link to RNA-mediated ecological adaptations, see:…

Read More

Impeaching the God of Abraham (9)

In “Impeaching the God of Abraham (7) I linked achiral glycine in position 6 of the GnRH decapeptide from peptide synthesis at the origin of life to the patent for naturally occurring light-activated carbon fixation and protonated RNA interference. See also: Regulatory Mechanisms of Vitellogenesis in Insects 1/28/21 …microRNA (miRNA) and nutritional (amino acid/Target of Rapamycin and insulin) pathways interplay with JH and 20E signaling cascades to control insect vitellogenesis. This article is part of the Research Topic Germ Cell…

Read More

Impeaching the God of Abraham (8)

2/22/21 In Case You Missed it. The cure for HIV and all other virus-driven pathology was announced today via an indexed publication found through my daily PubMed search for microRNA. Efficacy, accumulation, and transcriptional profile of anti-HIV shRNAs expressed from human U6, 7SK, and H1 promoters 12/31/20 & indexed on 2/22/21 announced “…a functional cure for HIV.” “The RNA polymerase III promoters H1, 7SK, and U6…” were linked to the cure or the effective treatment of all virus-driven diseases via…

Read More