Codon optimality vs systemic fraud (4)

A good model predicts. See: From Fertilization to Adult Sexual Behavior (1996). In our section on molecular epigenetics we predicted that A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins 6/16/22 would be linked to food energy and pheromone-regulated genetic processes of reproduction across kingdoms. On 6/23/22, that fact was placed back into the context of stupid theories. See: Abracadabra, One Becomes Two: The Importance of Context in Viral −1 Programmed Ribosomal Frameshifting  Yeast and potentially mammalian cells,…

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Epistemic corruption (10)

Biosynthesis of cyanobacterin, a paradigm for furanolide core structure assembly 5/26/22 Full functional evaluation of the recombinant key enzymes in vivo and in vitro, individually and in concert, provided in-depth mechanistic insights into a streamlined C–C bond-forming cascade that involves installation of compatible reactivity at seemingly unreactive Cα positions of amino acid precursors. Our work extends the biosynthetic and biocatalytic toolbox for γ-butyrolactone formation, provides a general paradigm for furanolide biosynthesis and sets the stage for their targeted discovery, biosynthetic…

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Epistemic corruption (9)

A prebiotically plausible scenario of an RNA–peptide world was reported in Science Magazine by Robert F. Service. See: How life could have arisen on an ‘RNA world’ 5/11/22 New evidence suggests RNA and peptides may have helped build each other on early Earth Researchers who study the origin of life have long considered RNA the central player because it can both carry genetic information and catalyze necessary chemical reactions. It was likely present on our planet before life evolved. But…

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Epistemic corruption (8)

What don’t you believe about these facts from 1910? I posted this video to Facebook one year ago, after a trip across the United States, which I chronicled in a series of other videos. Since then, “Cellulose” has linked fixation of amino acid substitutions to construction of the cell wall and microRNA-mediated protein folding chemistry via microRNA-mediated stem cell creation and healthy longevity across kingdoms. For examples of how energy-dependent ecological adaptations eliminate stupid theories about mutation-driven evolution, which link…

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MicroRNA-mediated existential threats (5)

I began a 10-part series on microRNA-mediated existential threats on 4/21/22. Part 5 shows how much progress can be made by those who do not accept censorship on social media. If you’re interested in the facts, see: Twitter accepts Musk’s $44 billion deal 4/25/22 “Free speech is the bedrock of a functioning democracy, and Twitter is the digital town square where matters vital to the future of humanity are debated,” Musk said in a statement. If Musk stops Twitter’s shadow…

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MicroRNA-mediated existential threats (2)

On 6/26/19, a friend and I stopped at the Scopes Museum in Dayton, Tennessee to make sure I could view this presentation on my laptop computer via a hotspot wi-fi connection. See: Genome-Wide Study Reveals a Novel Regulatory Pathway: Translation Affects mRNA Stability in a Codon-Dependent Manner 6/26/19 (available for free on demand with registration). I may try to find my pictures, or my on-location video to show that, as predicted, the presentation put an end to all the nonsense…

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MicroRNA-mediated existential threats (1)

See: RNA-mediated silencing (10) Second request for clarification. Do any of your #patents link naturally occurring light-activated #carbon_fixation in #cyanobacteria to biophysically constrained #microRNA-mediated protein folding #chemistry & #viral_endemicity across kingdoms via https://www.kickstarter.com/projects/geniusgames/cellulose-a-plant-cell-biology-game Cellulose Happy Easter! Thomas E. Ichim and others hold patents on food energy-dependent pheromone-regulated genetic processes of microRNA-mediated protein folding chemistry and the pH-dependent physiology of reproduction. Non-disclosure would be an existential threat to the microRNA-mediated future of humanity. See parts 1-10 of the series: The microRNA-mediated…

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RNA-mediated silencing (9)

WHO, the World Health Organization, thought you wouldn’t notice that your organizations were infiltrated by entitled feminists and stupid conspiracy theorists. See: Skirting the Matter of Feminism’s Culpability 4/4/22 “…true to feminist form, shifts to men and misogyny the blame for the epistemological collapse occurring in liberal democracies while ignoring the real culprit, feminism.” See also: RNA-mediated silencing (7) Three of the 4 articles that linked light-activated carbon fixation in cyanobacteria from microRNA-mediated protein folding chemistry across kingdoms were published…

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RNA-mediated silencing (8)

Now fully complete, human genome reveals new secrets 3/31/22 reports on: A next-generation human genome sequence 3/31/22 From telomere to telomere: The transcriptional and epigenetic state of human repeat elements 4/1/22 The complete sequence of a human genome 4/1/22 Epigenetic patterns in a complete human genome 4/1/22 Complete genomic and epigenetic maps of human centromeres 4/1/22 The articles and the reporting obfuscate the fact that God’s Creation of energy-as-information links sunlight and humidity to His Creation of all biodiversity on…

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RNA-mediated silencing (6)

See first RNA-mediated silencing (5) The AVONET database contains 11 morphological traits, such as beak shape and wing length, for 90,020 individual birds from 181 countries. It fails to link differences in uni-parental or bi-parental feeding from fixation of amino acid substitutions to the color of white-throated sparrows, which was linked to ethnic difference in skin color via chromosomal rearrangements across kingdoms via Estrogen receptor α polymorphism in a species with alternative behavioral phenotypes  1/13/14 The failure to link food…

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