RNA-Mediated

The 6-part series on Energy-dependent epigenetic translation to mRNA stability that ran here between 5/12/17 and 5/22/17 predictably links facts about energy-dependent microRNA-mediated chromosomal inheritance to the end of all the stupid theories that were touted by Gene Levinson in Rethinking Evolution: The Revolution That’s Hiding in Plain Sight (2021) See first: RNAi 2002 to AI 2021 (8) Light-activated microRNA biogenesis obviously links God’s energy-dependent Creation of the cell wall across kingdoms via: Biogenesis and Mechanisms of miRNA-Mediated Gene Regulation…

RNAi 2002 to AI 2021 (5)

January 1, 2022

Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Physics, RNA Directed, RNA interference, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity

In case you are a moronic public health fascist, liberal, atheist, or Communist who missed it, start your new year with facts about how to prevent or to effectively treat all virus-driven diseases. See: Footprints of a Singular 22-Nucleotide RNA Ring at the Origin of Life 4/25/20, Visualizing a protonated RNA state that modulates microRNA-21 maturation 10/26/20 and Peptide synthesis at the origin of life 11/13/20. Don’t wait another year to learn how to link energy-dependent biophysically constrained changes in…

RNAi 2002 to AI 2021 (1)

December 29, 2021

Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Nutrigenomics, Pharmacogenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity

Summary: Intelligent serious scientists have linked energy-dependent RNA interference (RNAi) to all biodiversity on Earth. For comparison, biologically uninformed theorists have nothing but mathematical models and Artificial Intelligence (AI). Human pheromones: integrating neuroendocrinology and ethology (2001) …the affect of pheromones on our emotions is linked to the effect of pheromones on the hormones of the hypothalamic-pituitary-gonadal axis –an unconscious affect. Based upon a detailed mammalian neuroendocrine model, Kohl [15] proposed that LH is the measurable link between sex and the…

microRNA-mediated cures (8)

December 24, 2021

Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity

A clear indicator of what is required to end the SARS-CoV-2 pandemic was published as: Host cell entry mediators implicated in the cellular tropism of SARS‑CoV‑2, the pathophysiology of COVID‑19 and the identification of microRNAs that can modulate the expression of these mediators (Review) 12/20/21 The pathophysiology of coronavirus disease 2019 (COVID‑19) is mainly dependent on the underlying mechanisms that mediate the entry of severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) into the host cells of the various human tissues/organs.…

microRNA-mediated cures (5)

December 13, 2021

Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations

“Dead” nucleotides are biophysically constrained pH-dependent single nucleotide substitutions (SNPs). See first: microRNA-mediated cures (4) Remember what’s been known for decades about dead nucleotides, nucleotide substitutions that are biophysically constrained, when you read about the prevention of bioterrorism and public health fascism in Imagination and remembrance: what role should historical epidemiology play in a world bewitched by mathematical modelling of COVID-19 and other epidemics? 6/7/21 …every established respiratory pandemic of the last 130 years has caused seasonal waves of infection…

microRNA-mediated cures (3)

December 6, 2021

Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News

See first: microRNA-mediated cures (2) For comparison to Genetic variations creating microRNA target sites…, and Nutrient-dependent/pheromone-controlled adaptive evolution, Masatoshi Nei claimed that nucleotide substitutions, insertion/deletion, segmental gene duplication, genomic duplication, changes in gene regulatory systems, transposition of genes, horizontal gene transfer et al., were mutations. Simply put, simple-minded theorists start with the idea that everything the happens to our supercoiled DNA is a mutation and they link mutations to evolution across billions to millions of years after energy-emerged from the…

microRNA-mediated cures (2)

December 2, 2021

Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, Neuronal Plasticity, Physics, replication timing, RNA editing, RNA interference, RNA–Mediated Epigenetic Heredity, What's in the News

If you find a recently published article that does not link “How microRNAs control cell division, differentiation and death” (2005) to healthy longevity instead of virus-driven diseases, please share it for comparison to “Advances in Genetics: Chapter One – miRNA, Development and Disease (2012) and Human pheromones and food odors: epigenetic influences on the socioaffective nature of evolved behaviors (3/15/12). Neo-Darwinian theorists and Big Bang cosmologists desparately need experimental evidence of energy-dependent top-down causation to support their stupid theories, and…

Orchestrated death of Jews et al., by Egyptians (1)

October 26, 2021

Adaptations, Alternative Splicings, Diseases & Disorders, Ecology, Human Brain, microRNA editing, Model Organisms, Neuronal Plasticity, RNA Directed, RNA interference, RNA-directed DNA methylation, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Variations

See first: Orchestrated death: Francis S. Collins (2) Exogenous miRNAs induce post-transcriptional gene silencing in plants 10/14/21 was reported on 10/21/21 as Plants Use RNA to Talk to Neighbors A study finds that plants sharing the same growth medium can exchange microRNAs that silence genes in the recipient, suggesting the nucleic acids may act as signaling molecules. Light-activated microRNA biogenesis in plants has been linked from food energy-dependent pheromone-regulated genetic processes of reproduction across kingdoms via the role of nucleic…

Orchestrated death: J. Michael Bailey

October 14, 2021

Adaptations, Autophagy, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, microRNA editing, Model Organisms, Neuronal Plasticity, Physics, RNA Directed, RNA interference, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations, What's in the News

A cis-acting structural variation at the ZNF558 locus controls a gene regulatory network in human brain development 10/7/21 Epigenetic manipulation of the human VNTR was sufficient to switch off ZNF558 expression and thereby increase SPATA18 expression. Our data reveal the co-option of a TE-controlling KZFP to regulate a protein-coding gene and how this regulatory network is controlled between species and human individuals by a cis-acting structural variation. Presumably, the molecular mechanisms are the same in people with gender dysphoria. Reported…

God’s microRNA-mediated Creation of genotypes (9)

October 5, 2021

Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations