Human Brain

Codon optimality vs systemic fraud (5)

June 27, 2022
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Nutrigenomics, Pharmacogenomics, Physics, replication timing, RNA Directed, RNA interference, RNA–Mediated Epigenetic Heredity, Subatomic, Variations
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Light-Controlled Recruitable Hybridization Chain Reaction on Exosome Vehicles for Highly Sensitive MicroRNA Imaging in Living Cells 6/27/22 links more than 144,000 other publications that mention miRNAs from Visualizing a protonated RNA state that modulates microRNA-21 maturation 10/26/20 to patented therapeutic solutions that help to protect organized genomes from the virus-driven degradation of messenger RNA. See: Results of Search in PGPUB Production Database and specifically: Nutraceuticals for the prevention, inhibition, and treatment of SARS-CoV-2 and associated COVID-19 The fact that natural selection…

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Crimes against humanity (1)

June 25, 2022
James Kohl
Adaptations, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, Nutrigenomics, Pharmacogenomics, Physics, Variations, What's in the News
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From Michigan State University Ask the expert: What is Juneteenth? Historical Perspective: See: “Apology to People of Color for APA’s Role in Promoting, Perpetuating, and Failing to Challenge Racism, Racial Discrimination, and Human Hierarchy in U.S.” October 29, 2021 When will this historic apology be celebrated? Did you even know about it? Michigan State’s Richard Lenski still promotes the moronic theory that racial differences evolved from nutrient-dependent pheromone-regulated genetic processes of reproduction in E. coli. See: Experimental Test of the…

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Codon optimality vs systemic fraud (4)

June 24, 2022
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News
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A good model predicts. See: From Fertilization to Adult Sexual Behavior (1996). In our section on molecular epigenetics we predicted that A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins 6/16/22 would be linked to food energy and pheromone-regulated genetic processes of reproduction across kingdoms. On 6/23/22, that fact was placed back into the context of stupid theories. See: Abracadabra, One Becomes Two: The Importance of Context in Viral −1 Programmed Ribosomal Frameshifting  Yeast and potentially mammalian cells,…

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Epistemic corruption (10)

May 26, 2022
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Nutrigenomics, Pharmacogenomics, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News
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Biosynthesis of cyanobacterin, a paradigm for furanolide core structure assembly 5/26/22 Full functional evaluation of the recombinant key enzymes in vivo and in vitro, individually and in concert, provided in-depth mechanistic insights into a streamlined C–C bond-forming cascade that involves installation of compatible reactivity at seemingly unreactive Cα positions of amino acid precursors. Our work extends the biosynthetic and biocatalytic toolbox for γ-butyrolactone formation, provides a general paradigm for furanolide biosynthesis and sets the stage for their targeted discovery, biosynthetic…

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Epistemic corruption (6)

May 16, 2022
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity
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Summary: The rapid pace of experimental evidence linked to Selective MicroRNA-Offset RNA Expression in Human Embryonic Stem Cells 3/30/15 can be compared to the nonsense touted by neo-Darwinian theorists published as Shining Light on the Evolution of Photosynthesis 12/1/03 Photosynthetic bacteria and eukaryotes collect light energy for photosynthesis in structures called light-harvesting antenna complexes. Unless the light-harvesting complexes automagically created themselves, the facts about God’s Creation of sunlight link light-activated carbon fixation in cyanobacteria to pH-dependent microRNA-mediated protein folding chemistry,…

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MicroRNA-mediated existential threats (4)

April 24, 2022
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
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See first:  MicroRNA-mediated existential threats (3) On 4/19/22 I posed this question on Twitter. Why do people believe stupid theories about the evolution of amino acid composition in proteins, which requires them to ignore everything known to intelligent serious scientists about how SARS-CoV-2 synthetic mRNA vaccinations altered biophysically constrained viral endemicity? 4/19/22 How can it not be perfectly clear that stupid theories about the evolution of amino acid composition in proteins ignore everything known to all intelligent serious scientists about…

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MicroRNA-mediated existential threats (3)

April 23, 2022
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News
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“Footprints of Multiple Interspecies Re-assortment Events” (4/16/18) link the failed efficacy of COVID19 vaccines,  to the microRNA-mediated future of humanity via patents held for therapeutic solutions by Thomas E. Eichim et al., in the context of former President Trump’s claim on 4/23/20 about light-activated protein folding chemistry and Characteristics of the MicroRNA Expression Profile of Exosomes Released by Vero Cells Infected with Porcine Epidemic Diarrhea Virus  (indexed on 4/23/22) Details: Exosomes… contain regulated microRNA (miRNA), allowing them to function in…

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MicroRNA-mediated existential threats (1)

April 17, 2022
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News
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See: RNA-mediated silencing (10) Second request for clarification. Do any of your #patents link naturally occurring light-activated #carbon_fixation in #cyanobacteria to biophysically constrained #microRNA-mediated protein folding #chemistry & #viral_endemicity across kingdoms via https://www.kickstarter.com/projects/geniusgames/cellulose-a-plant-cell-biology-game Cellulose Happy Easter! Thomas E. Ichim and others hold patents on food energy-dependent pheromone-regulated genetic processes of microRNA-mediated protein folding chemistry and the pH-dependent physiology of reproduction. Non-disclosure would be an existential threat to the microRNA-mediated future of humanity. See parts 1-10 of the series: The microRNA-mediated…

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RNA-mediated silencing (4)

March 21, 2022
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations, What's in the News
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Angel Trumpets are extinct in the wild. Daffodils are extremely well adapted. Other organisms and people who are not ecologically adapted suffer unnecessarily and die prematurely from the virus-driven degradation of mRNA. They do not evolve into different species. See first: RNA-mediated silencing (3) Robert H. Singer, co-authored: Single-molecule imaging of microRNA-mediated gene silencing in cells 3/17/22 Simultaneous visualization of single mRNAs, translation, and miRNA-binding revealed that miRNAs preferentially bind to translated mRNAs rather than untranslated mRNAs. Among other positions,…

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Photonics in Forensics (7)

March 10, 2022
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Variations, What's in the News
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Living with the Neanderthals 8/14/03 …Bear pleads for biologists to write clearly: “Don’t they realize how important it is to get the word out to everybody?” Social media censorship prevents people from learning the facts. All intelligent serious scientists and many intelligent people know that sunlight is beneficial in the context of biophotonics and forensics In the context of coronavirus pathology, this was stated clearly as US government experiments with simulations to show the coronavirus can ‘quickly’ be destroyed by…

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