RNA-Mediated

See first: Naturally attenuated viral endemicity (7) “MicroRNA-101-3p Modulates Mitochondrial Metabolism via the Regulation of Complex II Assembly 11/19/21 …we describe a new role for miR-101-3p as a modulator of mitochondrial metabolism via its regulation of multiple mitochondrial processes, including mtDNA transcription and complex II biogenesis.” See also: Weeklong improved colour contrasts sensitivity after single 670 nm exposures associated with enhanced mitochondrial function 11/24/21 Exposure to long wavelength light (650–900 nm) in animals improves mitochondrial function, increasing ATP production and…

Orchestrated death: J. Michael Bailey (2)

October 17, 2021

Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, RNA Directed, RNA interference, RNA–Mediated Epigenetic Heredity

See first: Orchestrated death: J. Michael Bailey See also: microRNA More than 129,000 indexed published works link light-activated carbon fixation and God’s Creation of humidity from pH-dependent peptide synthesis at the origin of life to biophysically constrained viral latency via the physiology of reproduction in Biblical Genesis. For comparison, Bill Taverner Admin of the Sex Ed FaceBook group unsubscribed me on 10/16/21. I wrote: Now do you understand the lack of public support for sex education? No intelligent person on…

Orchestrated death: J. Michael Bailey

October 14, 2021

Adaptations, Autophagy, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, microRNA editing, Model Organisms, Neuronal Plasticity, Physics, RNA Directed, RNA interference, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations, What's in the News

A cis-acting structural variation at the ZNF558 locus controls a gene regulatory network in human brain development 10/7/21 Epigenetic manipulation of the human VNTR was sufficient to switch off ZNF558 expression and thereby increase SPATA18 expression. Our data reveal the co-option of a TE-controlling KZFP to regulate a protein-coding gene and how this regulatory network is controlled between species and human individuals by a cis-acting structural variation. Presumably, the molecular mechanisms are the same in people with gender dysphoria. Reported…

God’s microRNA-mediated Creation of genotypes (9)

October 5, 2021

Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations

Watch for the 2021 Nobel Prize in Chemistry (10/6/21) to be linked from claims about the diet of moths and their physiology of reproduction to today’s resignation of NIH Director, Francis S. Collins, or to corruption among members of the Nobel Prize Committee. With few exceptions, awards in the “hard sciences” (Physics, Chemistry, Physiology and Medicine) link the light-activated proton motive force from the ATP-dependent Creation of microRNAs, RNA, and RNA interference to the pH-dependent physiology of reproduction across kingdoms…

God’s microRNA-mediated Creation of genotypes (8)

October 4, 2021

Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Subatomic

See first: God’s microRNA-mediated Creation of genotypes (7) The current issue of Science Magazine supports Trump’s claim via the claims in: Protein-coding repeat polymorphisms strongly shape diverse human phenotypes 9/23/21 The repeat polymorphisms vary with ethnicity, which explains the link from what different human populations eat to the pheromone-regulated genetic processes of reproduction across kingdoms from cyanobacteria to humans. See next: An integrated network analysis approach to identify potential key genes, transcription factors, and microRNAs regulating human hematopoietic stem cell…

God’s microRNA-mediated Creation of genotypes (7)

October 1, 2021

Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News

Molecular Biology Empowering a community publishing articles in Molecular Biology, including RNA biology, chromatin and epigenetics, gene expression, translation, DNA replication and repair, nuclear organization, gene editing, and much more. Advanced Search 13,006 results for microRNA Most recent: Herpes simplex virus 1 evades cellular antiviral response by inducing microRNA-24, which attenuates STING synthesis 9/30/21 See also: 43,893 results for viruses and Micrornas 73,770 results for Potential Therapeutic Effect of Micrornas See for comparison: More than 128,300 indexed publications on PubMed…

God’s microRNA-mediated Creation of genotypes (6)

October 1, 2021

Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News

microRNA 128,290 results. I was too busy to post links to articles when the total number of indexed publications hit 128,000. But see: Herpes simplex virus 1 evades cellular antiviral response by inducing microRNA-24, which attenuates STING synthesis 9/30/21 These results indicate possible therapeutic use of stable anti-miR-24, albeit administered by other routes, in diseases that are alleviated by STING. miR-24 is known to affect brain development and fetal neuronal differentiation [69]; however these effects should have little bearing on…

God’s microRNA-mediated Creation of genotypes (5)

September 21, 2021

Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Variations

Summary: Energy-dependent changes in single nucleotide polymorphisms (SNPs) in microribonucleic acids (microRNAs/miRNAs) were linked from femotosecond blasts of UV light to DNA repair via an extremely sensitive assay for the label-free optical detection and suppression of interfering effects caused by non-specific binding. Interactions in Augmented and Mixed Reality: An Overview 9/20/21 (This article belongs to the Special Issue Extended Reality: From Theory to Applications) All interactions are energy-dependent and microRNA-mediated. ~250 newly indexed articles attest to that fact, which is…

Natural selection for adaptation (10)

September 7, 2021

Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Variations

See: Ignoring light-activated microRNA biogenesis 10/16/18, and compare our section on pre-mRNAs and molecular epigenetics in: From Fertilization to Adult Sexual Behavior (1996) to MicroRNAs buffer genetic variation at specific temperatures during embryonic development 10/16/18, which was previously published sans mention of microRNAs as Temporal development of Drosophila embryos is highly robust across a wide temperature range 7/11/18 Changing the term from pre-mRNAs to microRNAs obfuscated food energy-dependent pheromone-regulated genetic processes of cause and effect, but see ~127,000 indexed publications…

Natural selection for adaptation (7)

August 31, 2021

Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, What's in the News