Human Pheromones

God’s protection from SARS COV-2 and other viruses (3)

December 17, 2020
James Kohl
Adaptations, Alternative Splicings, base editing, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, RNA Directed, RNA interference, RNA–Mediated Epigenetic Heredity, What's in the News
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The coronavirus may sometimes slip its genetic material into human chromosomes—but what does that mean? 12/16/20 …the paper clearly states the integration the authors think happens could not lead to the production of infectious SARS-CoV-2. That claim suggests that science fiction author, Greg Bear correctly linked nutrient-dependent pheromone-regulated ecological adaptations across kingdoms to the integration of SARS-CoV-2 and other viruses in organized human genomes via chromosomal rearrangements and sympatric speciation. See: Genotype (2021) In 1910 Thomas Hunt Morgan discovered some…

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Election day blues for fools who “voted blue” (3)

November 4, 2020
James Kohl
Adaptations, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, microRNA editing, Model Organisms, Neuronal Plasticity, Physics, RNA interference, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity, Subatomic
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See first: Election day blues for fools who “voted blue” (2) Medical experts rip Trump’s suggestion that sunlight, disinfectants may treat coronavirus President Donald J. Trump linked God’s Creation of subatomic particles from differences in the energy of positively charged protons and negatively charged electrons to biophysically constrained healthy longevity across kingdoms via the physiology of reproduction. If Biden wins, we are a nation of losers like Jonathan Reiner. Play Biden’s stupid game, wear masks, and practice social distancing, or…

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microRNA-mediated quantum error correction (3)

October 26, 2020
James Kohl
Adaptations, Alternative Splicings, Autophagy, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, RNA Directed, RNA interference
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See: microRNA-mediated quantum error correction (1) On 10/19/20, more than 250 additions to the indexed articles that mention the term ‘microRNA’ appeared after 5 days of what appeared to be a moratorium linked to publication of Thousands of Previously Unknown Phages Discovered in Whole-community Human Gut Metagenomes on 10/14/20. See also: Before Virus, After Virus: A Reckoning 10/15/20 The pandemic has energized us, yes, but it has also provided a necessary dose of humility. It has also been a call…

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The tipping point (revisited): 110K (2)

October 22, 2020
James Kohl
Adaptations, Alternative Splicings, base editing, biophotonics, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, microRNA editing, Neuronal Plasticity, Physics, RNA Directed, RNA interference
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Democrats seem to believe that President Trump’s claims about UV light and humidity have not been linked from the end of the COVID-19 nonsense to the end of their party, the end of Communism, the end of atheism, the end of racism and the end of all the liberal BS. Is the link from God’s Creation of UV light and water to ATP-dependent oxidative phosphorylation not perfectly clear to all intelligent people? See for review: From Fertilization to Adult Sexual…

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microRNA-mediated quantum error correction (2)

October 21, 2020
James Kohl
Adaptations, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, Model Organisms, Physics, RNA Directed, RNA interference
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What Fans of ‘Herd Immunity’ Don’t Tell You 10/19/20 …the White House has all but embraced herd immunity and has also poisoned the public with misinformation, making it all but impossible to get national, near-universal compliance with public health advice for the foreseeable future. Herd immunity exemplifies nutrient-dependent pheromone-controlled ecological adaptations, which annoys neo-Darwinian theorists and Big Bang cosmologists, especially those who also are Trump-haters. See for comparison: Robust Filtering and Noise Suppression in Intragenic miRNA-Mediated Host Regulation 9/21/20 Specifically,…

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The microRNA-mediated fight against COVID-19 (1)

August 21, 2020
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, Nutrigenomics, Pharmacogenomics, Physics, RNA interference, What's in the News
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History (1) Nutrient-dependent/pheromone-controlled adaptive evolution: a model (2013) …the epigenetic ‘tweaking’ of the immense gene networks that occurs via exposure to nutrient chemicals and pheromones can now be modeled in the context of the microRNA/messenger RNA balance, receptor-mediated intracellular signaling, and the stochastic gene expression required for nutrient-dependent pheromone-controlled adaptive evolution. History (2) Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems (2014 unpublished) This atoms to ecosystems model of ecological adaptations links nutrient-dependent epigenetic effects on base pairs and amino…

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pH-dependent viral latency (2)

May 24, 2020
James Kohl
Adaptations, Alternative Splicings, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Model Organisms, Neuronal Plasticity, RNA Directed, RNA interference, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, What's in the News
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New vaccines protect against COVID-19 in non-human primates, study finds 5/20/20 See for comparison: Vaccines do not control pandemics (1) 5/15/20 I reiterate: Emergence of Human G2P[4] Rotaviruses in the Post-vaccination Era in South Korea: Footprints of Multiple Interspecies Re-assortment Events 4/18/18 Amino acid substitutions at these positions were found to be associated with an inability to serotype a strain and are responsible for antigenic changes48. Recently, amino acid substitutions in the three main antigenic regions, especially at positions 96…

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The tipping point (revisited): 100K (3)

April 3, 2020
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, RNA Directed, RNA interference
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More than 100,000 indexed published works that mention microRNAs link the Creation of anti-entropic virucial light from light-activated microRNA biogenesis to RNA-mediated autophagy via the physiology of reproduction and biophysically constrained viral latency in all living genera. See for review: The tipping point (revisited): 100K (1) at MicroRNA-mediated.pro See for review: The tipping point (revisited): 100K (2) at Autophagy.pro Moving forward to what is known about how microRNAs are linked from RNAs to healthy longevity see: Autophagy regulation by microRNAs:…

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WHO’s ignorance: From roots to shoots (2)

March 24, 2020
James Kohl
Adaptations, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, Nutrigenomics, Pharmacogenomics, RNA interference, What's in the News
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WHO’s ignorance: From roots to shoots (1) Amino acid substitutions within or near the active site of the viral neuraminidase (NA) may affect influenza virus fitness. See: Neuraminidase inhibitor susceptibility and neuraminidase enzyme kinetics of human influenza A and B viruses circulating in Thailand in 2010–2015  The authors cite the World Health Organization’s Summary of neuraminidase amino acid substitutions associated with reduced inhibition by neuraminidase inhibitors” The summary is available as a pdf download. See also: Viral Factors Associated With…

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Natural models inspire future therapeutics (2)

June 24, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations, What's in the News
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Summary: Food odors and pheromones biophysically constrain viral latency, and an effective treatment for all neurodegenerative diseases was proposed in this 2011 patent application “Pheromones and the luteinizing hormone for inducing proliferation of neural stem cells and neurogenesis“ See for comparison: Identification of miR-379/miR-656 (C14MC) cluster downregulation and associated epigenetic and transcription regulatory mechanism in oligodendrogliomas. The post- transcriptionally regulatory network of this cluster showed enrichment of key cancer-related biological processes such as cell adhesion and migration. Also, there was…

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