Human Pheromones

Epigenetic inheritance of spatiotemporal regulation (2)

May 23, 2018
James Kohl
Adaptations, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, Model Organisms, Neuronal Plasticity, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations
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See: Epigenetic inheritance of spatiotemporal regulation Summary: Food energy-dependent changes in base pairs have repeatedly been linked to spatiotemporal regulation of mRNA translation via the pheromone-controlled physiology of reproduction and microRNA-mediated amino acid substitutions that stabilize organized genomes. See:  Thalamic WNT3 Secretion Spatiotemporally Regulates the Neocortical Ribosome Signature and mRNA Translation to Specify Neocortical Cell Subtypes One SNP rs4713668 (P=4.62 × 10−4) identified in our study, was in LD (r2=0.65) with rs3227, which is one of the three variants recently…

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Cracks in The Granite Wall (1)

May 17, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, What's in the News
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Researchers in Thailand linked US military service in Thailand during the time of the war in Vietnam from the time of the Korean War to denuclearization of North Korea via energy-dependent changes in the influenza B virus.   From scientific creationists in South Korea: A Single Amino Acid at the Polymerase Acidic Protein Determines the Pathogenicity of Influenza B Viruses   They obviously know how to create a virus that would decimate human populations in North Korea and in other…

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Kohl’s Laws of Biology (codon-optimality revisited)

May 11, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News
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Summary: Kohl’s Laws help to explain what was missing from Darwin’s ‘conditions of life.’ Darwin knew nothing about genetics, which means he knew nothing about the epigenetic effects of food odors or pheromones. Ancient hepatitis B viruses from the Bronze Age to the Medieval period 5/7/18 We provide evidence for the creation of HBV genotype A via recombination, and for a long-term association of modern HBV genotypes with humans, including the discovery of a human genotype that is now extinct.…

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Ecological adaptations vs the randomness of evolution (3)

May 8, 2018
James Kohl
Adaptations, base editing, biophotonics, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, microRNA editing, Model Organisms, RNA Directed
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Summary: Fifty years later, only theorists and other pseudoscientists have failed to recognize the facts that link experimental evidence of differences in the energy of photons to the proton motive force, which links the potential of hydrogen (pH) to biophysically constrained viral latency and all biodiversity on Earth. In that context, Carl Zimmer serves as an important example of human idiocy each time he makes claims about evolution. Serious scientists will meet during Schrödinger at 75 – The Future of…

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Nutrient-dependent pheromone-controlled feedback loops

May 3, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News
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Summary: The link from positive selection to one food energy-dependent base pair change and fixation of the mouse-model-to-human-specific EDAR V370A allele in populations on different continents attests to sympatric speciation at every level of examination that refutes the pseudoscientific nonsense of neo-Darwinian mutation-driven evolution. Reported on 5/3/18 as: SWAT team of immune cells found in mother’s milk  1) “There is a feedback loop,” says Yu. It’s known that some immune cells like leucocytes, another white blood cell that fights infection,…

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Ecological Adaptations vs the Randomness of Evolution

May 1, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, RNA Directed, RNA editing, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Variations
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Summary: Ecological variation is linked to ecological adaptations in all living genera via the creation of microRNAs and the sense of smell. Odor Perception on the Two Sides of the Brain: Consistency Despite Randomness Highlights •A random model predicts observed preservation of correlations in piriform responses •The model supports consistent agreement about odor quality among individuals The model fails to explain how the energy-dependent creation of microRNAs links pattern recognition to the creation of pre-mRNAs and biophysically constrained viral latency.…

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Plenty of Room at the Bottom

Environmental selection is natural selection (2)

April 26, 2018
James Kohl
Adaptations, base editing, biophotonics, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
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I believe that if you put enough biologically uniformed theorists in the same room, they will invent more theories to support the pseudoscientific nonsense they have touted in the past. See for example: Environmental selection during the last ice age on the mother-to-infant transmission of vitamin D and fatty acids through breast milk Acknowledgments The synthesis presented here is a product of the American Association for the Advancement of Science’s 2017 annual meeting, as the ideas came together in the…

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Environmental selection is natural selection

April 26, 2018
James Kohl
Adaptations, base editing, biophotonics, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, Nutrigenomics, RNA Directed, RNA-directed DNA methylation, RNA–Mediated Epigenetic Heredity, Variations
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Environmental selection during the last ice age on the mother-to-infant transmission of vitamin D and fatty acids through breast milk was published on April 23, 2018 The ectodysplasin A receptor (EDAR) gene has a range of pleiotropic effects, including sweat gland density, incisor shoveling, and mammary gland ductal branching. The frequency of the human-specific EDAR V370A allele appears to be uniquely elevated in North and East Asian and New World populations due to a bout of positive selection likely to…

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Psychophysical Laws of Biology: RNA-mediated nutritional psychiatry (3)

March 27, 2018
James Kohl
Adaptations, Alternative Splicings, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News
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Psychophysical Laws and the Superorganism  (open access) …superorganisms may also exhibit such behaviour, suggesting that these laws arise from fundamental mechanisms of information processing and decision-making. Reported on Jun 14, 2013 as Nutrient-dependent/pheromone-controlled adaptive evolution: a model and again on: Mar 27, 2018 as Honeybees may unlock the secrets of how the human brain works The study… found that superorganisms may obey the same laws as the human brain. Kohl’s “Laws of Biology” and Darwin’s “conditions of life” can now be…

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Autophagy in health and disease (1)

March 21, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, microRNA editing, Model Organisms, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
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Novel Treatment Strategies for the Nervous System: Circadian Clock Genes, Non-coding RNAs, and Forkhead Transcription Factors Each of these pathways have an intimate relationship with the programmed death pathways of autophagy and apoptosis and share a common link to the silent mating type information regulation 2 homolog 1 (Saccharomyces cerevisiae) (SIRT1) and the mechanistic target of rapamycin (mTOR). Circadian clock genes are necessary to modulate autophagy, limit cognitive loss, and prevent neuronal injury. Non-coding RNAs can control neuronal stem cell…

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