Human Pheromones

Light-activated error free DNA repair (2)

November 22, 2017
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
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Summary: In the diagram and diatribes that accompany claims about de novo changes in electrons and the production of nucleotides, the amount of pseudoscientific nonsense becomes perfectly clear. Pseudoscientists start with energy-dependent changes but call the changes de novo changes in electrons. That allows the pseudoscientists to dismiss any facts about how the creation of energy must be linked to the creation of enzymes. The creation of enzymes does not automagically occur and the creation of all biodiversity must occur…

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Schrodinger’s answer to Schrodinger’s question (2)

November 21, 2017
James Kohl
Adaptations, Diseases & Disorders, Human Pheromones, RNA Directed
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Summary: Neo-Darwinian pseudoscientific nonsense should never have achieved any level of acceptance — even among scientists who are biologically uninformed science idiots. Beyond blanket terms: Challenges for the explanatory value of variational (neuro-)ethology: Comment on “Answering Schrödinger’s question: A free-energy formulation” by Maxwell James Désormeau Ramstead et al Paywalled My summary: The commenters complain that the answer to Schrödinger’s question is framed in the context of a “Just-So” story. The theoretical construct places a “… spatio-temporal Markov blanket around the entire…

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MicroRNAs and the Cassandra syndrome (revisited)

November 20, 2017
James Kohl
Adaptations, Alternative Splicings, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, microRNA editing, Model Organisms, Nutrigenomics, RNA methylation, RNA-directed DNA methylation, Variations
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Conclusion: Serious scientists can explain every aspect of energy-dependent biophysically constrained viral latency in the context of details about these pathways and everything that links changes from electrons to ecosystems in all living genera. Why are the serious scientists still challenged by “…the tendency of academia to reject any academic-like work from outside academia?” What aspect of the academic contribution that could lead to the cure for all pathology do biologically uninformed academics want to continue to reject and attack?…

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A null mutation and healthy longevity?

November 17, 2017
James Kohl
Adaptations, Alternative Splicings, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity
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Summary: Food odors and pheromones biophysically constrain all pathology in species from microbes to humans. What kind of biologically uninformed science idiot leaves out everything known to serious scientists about the virus-driven degradation of messenger RNA and tells others they must falsify the neutral null theory that led to claims about a biophysically constrained beneficial “null mutation” in the Amish population of Berne, Indiana? Glutamylation Regulates Transport, Specializes Function, and Sculpts the Structure of Cilia Reported as: How to Control…

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Light-activated error free DNA repair

November 14, 2017
James Kohl
Adaptations, Alternative Splicings, base editing, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity
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Summary: The same set of microRNAs controls expression of the genes for rate-limiting enzymes, which control differences in the hormone production of different hormones in insects and crustaceans. That fact led to this claim in: The secret to safe DNA repair. …if you don’t have this enzyme, then this error-free repair is stopped. You can’t do it. If you can’t do the error-free repair, among other things that happen is that you expect these cells to be cancer prone. The…

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Epigenetic facts vs variable recombination theories

November 7, 2017
James Kohl
Adaptations, Alternative Splicings, base editing, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
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6/14/13 Nutrient-dependent/pheromone-controlled adaptive evolution: a model ….the model represented here is consistent with what is known about the epigenetic effects of ecologically important nutrients and pheromones on the adaptively evolved behavior of species from microbes to man. Minimally, this model can be compared to any other factual representations of epigenesis and epistasis for determination of the best scientific ‘fit’. 7/25/13 Jay R. Feierman: Variation is not nutrient availability and the something that is doing the selecting is not the individual…

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Selfish X-linked alleles and X chromosome inactivation

November 6, 2017
James Kohl
Adaptations, Alternative Splicings, base editing, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, RNA Directed, RNA editing, RNA-directed DNA methylation
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From Fertilization to Adult Sexual Behavior In our section on molecular epigenetics from 1996 we wrote: Genomic-imprinting is also manifest in specific parts of the X-inactivation region’s related XIST gene. Here male- and female-specific methyl-group patterns participate in X-inactivation in females and also in the preferential inactivation of the paternal X in human placentae of female concepti (Harrison, 1989; Monk, 1995). This process indicates that tissues of the early conceptus can sense and react differentially to epigenetic sexual dimorphisms on…

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Pheromones biophysically constrain RNA-mediated biodiversity (1)

November 3, 2017
James Kohl
Adaptations, Alternative Splicings, base editing, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, RNA Directed, RNA editing, Variations
One Comment

Elaine Morgan on paradigm shifts. Her view of the pseudoscientific nonsense touted by neo-Darwinian theorists and “Big Bang” cosmologists is humorous and she accurately represents what’s been happening to me and others like me for the past two decades. It’s what we expect. It’s your choice to keep laughing about it. See for comparison: Functional screening in human cardiac organoids reveals a metabolic mechanism for cardiomyocyte cell cycle arrest Reported as: Scientists have identified the metabolic pathway associated with heart…

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Pheromones biophysically constrain base editing and RNA editing

November 2, 2017
James Kohl
Adaptations, Alternative Splicings, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, What's in the News
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Summary: …they [Koonin’s group] substitute what they consider to be a plausible hypothesis. It places their observations into the context of a universal trend that is conserved in all life after the trend emerged, which was sometime before the last universal common ancestor of all extant organisms emerged and began to evolve. Social behaviour shapes hypothalamic neural ensemble representations of conspecific sex Published online 18 October 2017 The vibrational theory of olfaction for the win Published 31 October 2017 Neuronal…

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From base editing to RNA editing (5)

November 1, 2017
James Kohl
Adaptations, Alternative Splicings, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Nutrigenomics, RNA Directed, RNA editing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity
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1) Maturity’ molecule helps adolescent brain grow up   2) Geneticists are starting to unravel evolution’s role in mental illness: Hints emerge that past environments could have influenced psychiatric disorders   Please try to link the maturity molecule to the evolution of mental illness outside the context of food energy-dependent base editing, RNA editing, RNA-mediated amino acid substitutions and the pheromone-controlled physiology of reproduction that stabilizes the organized genomes of all living genera via chromosomal rearrangements.   Then see:Oppositional COMT…

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