Human Pheromones

From base editing to RNA editing (4)

November 1, 2017
James Kohl
Adaptations, Alternative Splicings, base editing, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
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Summary: To claim evolution, Koonin must link food energy from the pheromone-controlled physiology of reproduction to fixation of a beneficial mutation in the organized genome of one species that evolved into another species. Search Results for “base editing” = 82 blog posts starting with Cell-type differentiation on February 7, 2014 Search Results for “RNA editing” = 95 blog posts starting with In theory, or supported by experimental evidence? October 22, 2014 See for comparison PubMed: “base editing” (33 citations) and…

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Energy as information and Infowars

October 31, 2017
James Kohl
base editing, Cytosis, Diseases & Disorders, Human Pheromones, Model Organisms, RNA Directed, RNA editing, RNA-directed DNA methylation
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Conclusion: The release of the game “Cytosis” supports science via the ability of personalized learning to teach anyone over the age of 10 that the anti-entropic virucidal energy of sunlight exemplifies energy as information and the virus-driven degradation of messenger RNA links mutations to all pathology. Unique Visual Stimulation May be New Treatment for Alzheimer’s Using LED lights flickering at a specific frequency, MIT researchers have shown that they can substantially reduce the beta amyloid plaques seen in Alzheimer’s disease,…

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From base editing to RNA editing (3)

October 31, 2017
James Kohl
Adaptations, Alternative Splicings, base editing, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
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Summary: Claims about spontaneous deamination fail to link energy-dependent changes from base editing to RNA-mediated DNA repair of damage caused by the virus-driven degradation of messenger RNA. Highly efficient RNA-guided base editing in mouse embryos 27 February 2017 They reported the use of RNA-programmable deaminases to make various animal models with single amino-acid substitutions.They linked the single amino acid substitutions from the correction of nonsense mutations in the future to the correction of genetic defects in human embryos. Reported as:…

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From base editing to RNA editing (2)

October 27, 2017
James Kohl
Adaptations, base editing, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, Model Organisms, RNA Directed, RNA editing, RNA-mediated epigenetic regulation of gene expression, Variations
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Summary: The link from the creation of the sun’s anti-entropic virucidal energy and the physiology of pheromone-controlled reproduction to fixation of RNA-mediated amino acid substitutions in the organized genomes of all living genera is all that is required to claim adaptation for comparison to Koonin’s moronic assertion that the amino acid composition of proteins varies because the composition evolved. Digital reconstruction of the Ceprano calvarium (Italy), and implications for its interpretation A “fresh” (i.e., not yet “fossil”) bone can be…

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Loss of energy as information (1)

October 24, 2017
James Kohl
Adaptations, Alternative Splicings, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News
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Summary: Koonin claims that the theories of population geneticists have replaced what he calls the just-so stories of adaptationists with testable predictions. He claims that serious scientists should attempt to falsify the ridiculous theories touted by people like him, so that the ongoing use of ridiculous mathematical models can improve our understanding of evolution. I think Koonin may be attempting to address the concerns brought forward after another biologically uninformed science idiot claimed that my refutation of neo-Darwinian pseudoscientific nonsense…

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Long-term adaptation replaces evolution (3)

October 23, 2017
James Kohl
Adaptations, Alternative Splicings, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, RNA Directed, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations, What's in the News
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Summary: Koonin thinks that serious scientists who have linked the creation of energy to all biodiversity via the physiology of pheromone-controlled reproduction in species from microbes to humans must prove that everything the serious scientists know did not occur randomly after the sun’s anti-entropic virucidal energy emerged from nothing. Other pseudoscientists have taken a step towards refuting Koonin’s moronic claim with publication of: A mammalian blood odor component serves as an approach-avoidance cue across phylum border – from flies to…

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Long-term adaptation replaces evolution (2)

October 23, 2017
James Kohl
Adaptations, Alternative Splicings, Autophagy, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Model Organisms, Nutrigenomics, Physics, RNA-directed DNA methylation, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity
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The food energy-dependent “doubling up” on ‘junk DNA’ is biophysically constrained by the physiology of pheromone-controlled reproduction. The metabolism of food to species-specific pheromones links the conserved molecular mechanisms of RNA-mediated cell type differentiation in all individuals of all living genera to healthy longevity via what is known about amino acid substitutions in supercoiled DNA, which link energy-dependent changes in chirality to autophagy. Supercoiled DNA is far more dynamic than the ‘Watson-Crick’ double … Researchers have imaged in unprecedented detail the…

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For God and Country

Losers: Rediscovering an epigenetic key (2)

October 17, 2017
James Kohl
Adaptations, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, Neuronal Plasticity, RNA Directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression
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Genome-wide meta-analysis associates HLA-DQA1/DRB1 and LPA and lifestyle factors with human longevity “Validation of associations reported elsewhere,” includes the detailed associations from 1996 in the molecular epigenetics section of: From fertilization to adult sexual behavior  and in my 2013 refutation of neo-Darwinian theories: Nutrient-dependent/pheromone-controlled adaptive evolution: a model  (Val370Ala is also known as rs3827760, also known as 1540T/C, 370A. It is a SNP in the ectodysplasin A receptor EDAR gene on chromosome 2.) Excerpt: Two additional recent reports link substitution…

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For God and Country

Faith in evolution: Paleontology as a molecular science

October 16, 2017
James Kohl
Adaptations, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, RNA Directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Subatomic
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Keeping the faith For the last 20 years, Mary Schweitzer, a paleontologist at North Carolina State University in Raleigh, has amassed a wealth of evidence that she’s isolated protein fragments from dinosaurs as much as 80 million years old. That bucks the conventional wisdom among paleontologists who argue that proteins, which are made of chains of amino acids, can’t survive more than 1 million years or so. So far, no group other than Schweitzer and her collaborators has managed to…

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Lethal virus kills 5 billion people?

Until death: Virus-driven failure of multisensory integration (3)

October 13, 2017
James Kohl
Adaptations, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Model Organisms, Neuronal Plasticity, Physics, RNA Directed, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News
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What Your Nose Knows: Sense of Smell and Your Health August 2016 What the Nose Knows May Affect Your Brain Health October 2017 Doty’s research found a strong connection between low scores on a 40-item smell test and damage to this area of the brain. His recent article in The Lancet outlines possible ways that sense of smell and overall brain health could be linked and “may be the genesis of many neurodegenerative diseases. See: ”Olfactory dysfunction in neurodegenerative diseases:…

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