Light Energy

The eternal significance of microRNAs (1)

April 10, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
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Common Allele Linked to Sugar Consumption Leads to Lower Body Fat, Higher Blood Pressure One energy-dependent change in a base pair is linked from the FGF21 rs838133 variant to microRNA-mediated changes in morphology and behavior. The quantized energy as information link from microRNAs to morphology and behavior is common to my mouse-to-human model of sympatric speciation. By linking the common allele to sugar consumption, the authors attest to the fact that sympatric speciation is quantized energy-dependent. Energy as information biophysically constrains…

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Sympatric speciation vs pseudoscientic nonsense (2)

April 7, 2018
James Kohl
Adaptations, Autophagy, Diseases & Disorders, Ecology, Light Energy
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This is how intermittent fasting protects us from viruses in the context of using stored fat for quantized energy-dependent RNA-mediated DNA repair. Fat cells converted into stem cells can repair any damaged tissues (video 3:48) Some whales use the molecular mechanisms of quantized energy-dependent RNA-mediated DNA repair during their migration, which is when they may not eat anything until after completing their route. See for details: Energy as information and constrained endogenous RNA interference (video 6:46) Feedback loops link quantized…

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Laws of Biology / Rules of Life

April 3, 2018
James Kohl
Adaptations, Cytosis, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Physics, RNA Directed, Subatomic, What's in the News
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Summary: Slide number 6 clearly states the “Levels of Biological Organization” that the “NSF’s 10 Big Ideas” finally places into the context of what has been known to all serious scientists for more than a century. Simply put, Hugo de Vries definition of mutation (sudden energy jumps) should never have been accepted as anything besides the claim of a biologically uninformed science idiot. Instead, the definition bastardized every aspect of what is now known about biophysically constrained viral latency and…

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NSF’s parrot and other parrots

April 3, 2018
James Kohl
Adaptations, biophotonics, Diseases & Disorders, Ecology, Light Energy, Physics, Subatomic, Variations
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Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation” (1964) “Isolated thymus nuclei transport amino acids into an intranuclear pool by a process which seems to depend on energy from nuclear ATP synthesis (20).” The energy must be biophysically constrained: Long-range coherence and energy storage in biological systems (1968) Human Pheromones: Linking Neuroendocrinology and Ethology (revisited) (2010) Slide # 6 attests to the fact that the levels of biological organization…

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Less evolvable RNA-mediated ecological adaptations

March 29, 2018
James Kohl
Adaptations, Cytosis, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
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No experimental evidence of biophysically constrained RNA-mediated cell type differentiation supports the claim about “…the evolutionary plasticity of the regulatory regions involved in transcriptional regulation…” The overwhelming systems complexity of energy-dependent RNA-mediated cause and effect can no longer be placed into the context of the pseudoscientific nonsense touted by theorists. Watch Andrea Wagner’s group try to escape from the claims made by losers. But first see: Kalevi Kull: Censorship & Royal Society Evo Event Nobody wants to belong to the…

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Let there be anti-entropic virucidal light

March 28, 2018
James Kohl
Adaptations, biophotonics, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Physics, RNA Directed, RNA-mediated epigenetic regulation of gene expression, What's in the News
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Summary: This is a lie! …theories are too detailed to be included in models that study host-phage interactions in the long term, which hinders our understanding of systems that range from pathogens infecting gut bacteria to marine phage shaping present and future oceans. Fuelling the future In his short story ‘Let There Be Light’, the science-fiction author Robert A Heinlein introduced the energy source that would power his Future History series of stories and novels. In The Darwin Code, Greg…

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Psychophysical Laws of Biology: RNA-mediated nutritional psychiatry (3)

March 27, 2018
James Kohl
Adaptations, Alternative Splicings, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News
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Psychophysical Laws and the Superorganism  (open access) …superorganisms may also exhibit such behaviour, suggesting that these laws arise from fundamental mechanisms of information processing and decision-making. Reported on Jun 14, 2013 as Nutrient-dependent/pheromone-controlled adaptive evolution: a model and again on: Mar 27, 2018 as Honeybees may unlock the secrets of how the human brain works The study… found that superorganisms may obey the same laws as the human brain. Kohl’s “Laws of Biology” and Darwin’s “conditions of life” can now be…

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Part 3: Light-controlled cell biology (revisited)

March 23, 2018
James Kohl
Adaptations, Autophagy, biophotonics, Diseases & Disorders, Ecology, Light Energy, Physics, RNA Directed, RNA interference, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Variations
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Your cells are constantly being shed and replaced—so is your body ever completely refreshed? Does anything remain of the body that existed on Jan. 1, 2017? 2007? The day you were born? (video) Out of Order: Undaunted  …as I prepared for this issue’s Special Report on Microbiomics (starting on page 19), I am stunned by what I am only starting to understand. That our individual existence as humans may only be 10 percent of what we see in the mirror—and…

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Light-controlled cell biology (revisited)

March 21, 2018
James Kohl
Adaptations, Autophagy, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations, What's in the News
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See Sci-Bay Scholar for citations and downloads of more than 3300 published works that link viruses to microRNAs Summary: …either the organized genomes of all cell types use the energy source, or viruses use the biophysically constrained energy of the cell types. No extant species can be used as an example of how the virus-driven theft of quantized energy can be linked from natural selection to the evolution of a new species. See also, with my emphasis: Light Offers New…

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Autophagy in health and disease (1)

March 21, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, microRNA editing, Model Organisms, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
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Novel Treatment Strategies for the Nervous System: Circadian Clock Genes, Non-coding RNAs, and Forkhead Transcription Factors Each of these pathways have an intimate relationship with the programmed death pathways of autophagy and apoptosis and share a common link to the silent mating type information regulation 2 homolog 1 (Saccharomyces cerevisiae) (SIRT1) and the mechanistic target of rapamycin (mTOR). Circadian clock genes are necessary to modulate autophagy, limit cognitive loss, and prevent neuronal injury. Non-coding RNAs can control neuronal stem cell…

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