Neuronal Plasticity

Who created your virus-driven death gene? (2)

Evolution of Constrained Gonadotropin-releasing Hormone Ligand Conformation and Receptor Selectivity These findings indicate that the substitution of glycine for a chiral amino acid in GnRH during evolution allows a more constrained conformation for receptor binding and that this subtle single amino acid substitution in a site remote from the ligand functional domains has marked effects on its structure and activity. The difference between an energy-dependent RNA-mediated amino acid substitution and a mutation has been largely ignored as pseudoscientists linked accidents…

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The overwhelming ignorance of sex researchers

Summary: J. Michael Bailey, and others like him, pretend to not know how non-coding variants are epigenetically linked from differences in hydrogen bonds to all energy-dependent biophysically constrained morphological and behavioral phenotypes. Genome-Wide Association Study of Male Sexual Orientation [Energy-dependent changes in biophysically constrained viral latency] We identified several [energy-dependent changes in] SNPs with p < 10−5, including regions of multiple supporting SNPs on chromosomes 13 (minimum p = 7.5 × 10−7) and 14 (p = 4.7 × 10−7). The genes nearest to these peaks have functions plausibly relevant to…

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Mouse morphs and primate diversity in 50 years

Excerpt: Analysis of the crystal structure of deer mouse Hb at 1.8 Å resolution (24, 25) revealed that each of the eight rHb mutants is characterized by a unique constellation of hydrogen bonds within and between subunits (Table 2 and fig. S2). Additional hydrogen bonds between subunits of the same αβ dimer are formed in the presence of β128Ser (an L-type residue; fig. S2), which contributes to the observed epistasis between allelic α- and β-chain variants. ——————————— Energy-dependent RNA-mediated biophysically…

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Exposing the 2nd Law to more ridicule (1)

Summary: Experiment demonstrates quantum mechanical effects from biological system Schrödinger (1944) linked the anti-entropic virucidal energy of sunlight from the physiology of pheromone-controlled reproduction in soil bacteria to all biodiversity. He then began to suspect that his colleagues, who displayed human idiocy, would kill him – if ever again he reasserted the facts. After 1944, Richard P. Feynman took a stand against the human idiocy, and lost. He was not killed, just ignored. Ignorance prevails. It always has. The virus-driven…

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Light-activated error free DNA repair (2)

Summary: In the diagram and diatribes that accompany claims about de novo changes in electrons and the production of nucleotides, the amount of pseudoscientific nonsense becomes perfectly clear. Pseudoscientists start with energy-dependent changes but call the changes de novo changes in electrons. That allows the pseudoscientists to dismiss any facts about how the creation of energy must be linked to the creation of enzymes. The creation of enzymes does not automagically occur and the creation of all biodiversity must occur…

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Schrodinger’s answer to Schrodinger’s question

There is no such thing as de novo control of electrons or self-assembly. Answering Schrödinger’s question: A free-energy formulation The free-energy principle (FEP) is a formal model of neuronal processes that is widely recognised in neuroscience as a unifying theory of the brain and biobehaviour. More recently, however, it has been extended beyond the brain to explain the dynamics of living systems, and their unique capacity to avoid decay. They don’t understand the question that Schrodinger answered. He linked the…

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A null mutation and healthy longevity?

Summary: Food odors and pheromones biophysically constrain all pathology in species from microbes to humans. What kind of biologically uninformed science idiot leaves out everything known to serious scientists about the virus-driven degradation of messenger RNA and tells others they must falsify the neutral null theory that led to claims about a biophysically constrained beneficial “null mutation” in the Amish population of Berne, Indiana? Glutamylation Regulates Transport, Specializes Function, and Sculpts the Structure of Cilia Reported as: How to Control…

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Epigenetic facts vs variable recombination theories

6/14/13 Nutrient-dependent/pheromone-controlled adaptive evolution: a model ….the model represented here is consistent with what is known about the epigenetic effects of ecologically important nutrients and pheromones on the adaptively evolved behavior of species from microbes to man. Minimally, this model can be compared to any other factual representations of epigenesis and epistasis for determination of the best scientific ‘fit’. 7/25/13 Jay R. Feierman: Variation is not nutrient availability and the something that is doing the selecting is not the individual…

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From base editing to RNA editing (4)

Summary: To claim evolution, Koonin must link food energy from the pheromone-controlled physiology of reproduction to fixation of a beneficial mutation in the organized genome of one species that evolved into another species. Search Results for “base editing” = 82 blog posts starting with Cell-type differentiation on February 7, 2014 Search Results for “RNA editing” = 95 blog posts starting with In theory, or supported by experimental evidence? October 22, 2014 See for comparison PubMed: “base editing” (33 citations) and…

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Loss of energy as information (1)

Summary: Koonin claims that the theories of population geneticists have replaced what he calls the just-so stories of adaptationists with testable predictions. He claims that serious scientists should attempt to falsify the ridiculous theories touted by people like him, so that the ongoing use of ridiculous mathematical models can improve our understanding of evolution. I think Koonin may be attempting to address the concerns brought forward after another biologically uninformed science idiot claimed that my refutation of neo-Darwinian pseudoscientific nonsense…

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  • What Darwin proved: there’s no such thing as a species
    GENETICS As Animals Mingle, a Baffling Genetic Barrier A short stretch of DNA is challenging what it means to be a species. By: Emily Singer August 5, 2014 Excerpt: “Scientists have dubbed such regions of the genome “islands of speciation.” The persistence of such islands is a phenomenon that has been observed in a variety of […]
  • Randomness and Divine Providence
    A Q&A on randomness and God’s providence …the main goal is to really put together a collection of scholarly studies of these issues: physicists, biologists, […]
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