Neuronal Plasticity

Optogenetics replaces fMRI but not pseudoscientific nonsense

Summary: The ability to evaluate spaciotemporal influences on health compared to virus-driven pathology must include a link from quantized energy to the creation of ATP and the creation of RNA. Hunting people down who are aware of that fact is difficult because most of them have ignored the facts from this 1964 publication. Ed Boyden and Optogenetics: The Future of Neuroscience (video) (transcript) What I’m trying to do now is see whether we can help people pilot crazy projects that…

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A fear of pheromones (revisited)

Neurotransmitter Switching Regulated by miRNAs Controls Changes in Social Preference Reported as: Scents and social preference: Neuroscientists ID the roots of attraction “MicroRNAs were ideal candidates for the job,” said Lippi, a project scientist in Berg’s laboratory in the Division’s Neurobiology Section. “They are post-transcriptional repressors and can target hundreds of different mRNAs to consolidate specific genetic programs and trigger developmental switches.” Energy-dependent changes in the microRNA/messenger RNA balance link the physiology of pheromone-controlled reproduction to all healthy longevity in…

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Host-derived creation of all pathology (2 of 2)

Summary: All serious scientists know that all epigenetic diversity is food energy-dependent and biophysically constrained by the pheromone-controlled physiology of reproduction. See for comparison: Jay R. Feierman: “Variation is not nutrient availability and the something that is doing the selecting is not the individual organism. A feature of an educated person is to realize what they do not know. Sadly, you don’t know that you have an incorrect understanding [of] Darwinian biological evolution.” A Bacterial Messenger Molecule Extends Healthspan …indole,…

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Host-derived creation of all pathology (1 of 2)

Hunter-gatherers’ seasonal gut-microbe diversity loss echoes our permanent one For more than 15 million years, human beings have co-evolved with thousands of microbial species… Nothing known to serious scientists support ridiculous claims about 15 million years. See for comparison: Natural Selection on the Olfactory Receptor Gene Family in Humans and Chimpanzees See also: Nothing in Biology Makes Any Sense Except in the Light of Evolution …the so-called alpha chains of hemoglobin have identical sequences of amino acids in man and…

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Stem cells do not create themselves

Summary: The energy-dependent cellular pathways have been detailed at all levels of examination from atoms to ecosystems in the context of physics, chemistry, and molecular epigenetics. The mere mention of RNA-mediated amino acid substitutions may cause theorists to panic because it eliminates their pseudoscientific nonsense in the context of the claim that proteins do not create themselves. Stromal R-spondin orchestrates gastric epithelial stem cells and gland homeostasis 1) The constant regeneration of stomach epithelium is driven by long-lived stem cells1,…

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Pseudoscientists hate what science explains! (3)

See also: Pseudoscientists hate what science explains (2) Summary: In addition to germline silencing via information transfer to the physical landscape of supercoiled DNA, multicopy transgene arrays are linked from changes in the microRNA/messenger RNA balance to variation in their somatic expression level. That fact helps to establish the difference between healthy longevity and pathology across generations. Problems with DNA replication can cause epigenetic changes that may be inherited for several generations My summary: The polycomb repressive complex 2, additional…

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Energy and neural plasticity

Summary: Food energy is required because proteins do not create themselves and virus-driven energy theft causes the degradation of messenger RNA in all living genera. See for comparison: Neural plasticity wanes with age, but increasing the protein Arc—abundant earlier in life—in the visual cortex of mice can fend off this decline. The restoration of neural plasticity requires the food energy-dependent pheromone-controlled de novo creation of genes. For example, see: Natural Selection on the Olfactory Receptor Gene Family in Humans and Chimpanzees Desperate…

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The Origin of Information (4)

Summary: Others have learned that the energy in a hydrogen atom must be linked to all biodiversity on Earth. The question is: “Where did the energy in the hydrogen atom come from?” See: The Origin of Information (3) Finally, someone is asking questions that can be summarized in one question (see below). Until now, on the International Society for Human Ethology’s Yahoo group, and elsewhere, the moderator: Jay R. Feierman has prevented the dissemination of accurate information on this topic.…

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Can protein folding chemistry be understood by theorists?

Excerpt: The researchers believe their discovery dovetails with their research on how tumor viruses and cancer mutations change a cell’s DNA structure and organization to cause uncontrolled cell growth. Aye group discovers avenue for precision cancer treatment One challenge is that multiple variations, or isoforms, of the same protein can all catalyze the same cellular function, “but the nuances of biology rest in how individual isoforms are regulated,” Aye said. Natural selection for energy-dependent codon optimality regulates the creation of…

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Irreconcilable differences: food energy vs de novo assembly

Developmental dynamics and contemporary evolutionary psychology: status quo or irreconcilable views? Reply to Bjorklund (2003), Krebs (2003), Buss and Reeve (2003), Crawford (2003), and Tooby et Al. (2003). The authors argue that evolutionary psychology currently offers no coherent framework for how to integrate genetic, environmental, and experiential factors into a theory of behavioral or cognitive phenotypes. An evolutionary perspective on the systems of adaptive immunity We propose a revival of the concept of the ‘Big Bang’ of vertebrate immunity, arguing…

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  • What Darwin proved: there’s no such thing as a species
    GENETICS As Animals Mingle, a Baffling Genetic Barrier A short stretch of DNA is challenging what it means to be a species. By: Emily Singer August 5, 2014 Excerpt: “Scientists have dubbed such regions of the genome “islands of speciation.” The persistence of such islands is a phenomenon that has been observed in a variety of […]
  • Randomness and Divine Providence
    A Q&A on randomness and God’s providence …the main goal is to really put together a collection of scholarly studies of these issues: physicists, biologists, […]
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