Model Organisms

Light-activated carbon fixation did not evolve (5)

See first: The tipping point (revisited): 120K 5/12/21 Church Speaks: The cyanobacteria fix [carbon via] light…Under ideal circumstances, they can be maybe seven to ten times more productive per photon.” George M. Church et al patented this naturally occurring process. On 5/12/21, I was pleasantly surprised to see the facts represented in this trail-side placard at Canyonlands National Park. The facts make this patent worthless: RNA-Guided Human Genome Engineering See why: Light-activated binding together of sand and other soil particles…

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Quantum biology vs atheism (1)

Peptide synthesis at the origin of life links quantum coherence to coherently organized biology via biophysically constrained viral latency. See: Identification of a micropeptide and multiple secondary cell genes that modulate Drosophila male reproductive success 4/13/21 A noncoding RNA generates amino acid peptides and energy-dependent sperm-competition phenotypes. Moving forward across species, see: Circular RNAs: Novel potential regulators in embryogenesis, female infertility, and pregnancy‐related diseases 4/20/21 Circular RNAs (circRNAs) are endogenous noncoding RNAs with unique cyclic structures. Although they were previously considered…

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Quantum Darwinism (9)

Beyond the Elements: Life (video with transcript) There was a turning point, the evolution of a transformative series of chemical reactions that, over time, remade the planet… They place God’s Creation of sunlight and humidity at the origin of life (THE turning point) into the context of experimental evidence of enzyme-dependent directed evolution, which requires this stupid assumption from 2005. “Amino acid composition of proteins varies substantially between taxa and, thus, can evolve.” Enzymes are proteins. No experimental evidence of…

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Quantum Darwinism (5)

See with my added emphasis: Parallel genetics of regulatory sequences using scalable genome editing in vivo 4/13/21 [Energy-dependent biophysically-constrained microRNA-mediated] Regulatory elements must ultimately be understood within their genomic environment and development- or tissue-specific contexts. Gene-centric theorists are too stupid to start with God’s Creation of energy, which must be linked from regulatory elements to regulation of the genomic environment before the effects of energy can be understood in any context whatsoever. See for context: Energy as information and constrained…

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Quantum Darwinism (2)

Nonenzymatic polymerase-like template-directed synthesis of acyclic l-threoninol nucleic acid 2/5/21 Orgel and Szostak introduced an amino group into 2′- and 3′-positions9, which enabled effective RNA copying due to acceleration of the ligation reaction10,11. Reported as: Origins of life could have started with DNA-like XNAs 4/6/21 …shorter L-aTNA fragments came together and linked up with each other on the longer L-aTNA template. Critically, this happened in the presence of a compound, called N-cyanoimidazole, and a metal ion, like manganese, both of…

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Quantum Darwinism (1)

See first: Pheromones protect us from viruses parts 1-10 For a historical perspective on the development of healthy ecosystems, see: Pheromonal Regulation of Genetic Processes: Research on the House Mouse (Mus musculus L.) (1994) and From Fertilization to Adult Sexual Behavior (1996) For links from quantum Darwinism to all energy-dependent biophysically constrained biodiversity, see also: Quantum Criticality at the Origin of Life 3/3/15 The number of proteins grows exponentially with the number n of amino acids… Peptide synthesis at the…

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Pheromones protect us from viruses (10)

Twitter Profile: MicroRNA.pro, http://Autophagy.pro & http://RNA-mediated.com link subatomic particles from pH-dependent peptide synthesis to sympatric speciation and healthy ecosystems. Before 4/6/21, I had contributed 40,000 tweets @microRNApro to support claims about how light-activated carbon fixation is linked to healthy longevity in more than 118,400 indexed publications that mention ‘microRNA.’ For a historical perspective on the development of healthy ecosystems, see: Pheromonal Regulation of Genetic Processes: Research on the House Mouse (Mus musculus L.) (1994) “The specificity of pheromonal regulation depends…

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Pheromones protect us from viruses (7)

It’s been more than one year since Guenther Witzany published What is Life? 3/18/20 “A new definition of life must integrate the current empirical knowledge about interactions between cells, viruses, and RNA networks to provide a better explanatory power than the twentieth century narrative.” The need for the new definition of life is consistent with my claims from “What is life when it is not protected from virus-driven entropy.” It’s been 5 years since this virtual conference presentation on 3/30/16. The…

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Pheromones protect us from viruses (6)

The Origin of Species (1859) linked the observations of Charles Darwin from his “conditions of life” to all biodiversity on Earth via the physiology of reproduction in all species. Scientific progress across disciplines has since linked his claims to an effective treatment, protonated RNA interference, for virus-driven pathology. See: Direct Observation of Protonation State Modulation in SARS-CoV-2 Main Protease upon Inhibitor Binding with Neutron Crystallography 3/23/21 Our recent neutron crystallographic study of the ligand-free SARS-CoV-2 Mpro provided direct visualization of…

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Pheromones protect us from viruses (5)

Timothy Normand Miller (Digital circuit designer, software engineer, master debugger, computer engineering PhD, former college professor) @theosib2 wrote: If they didn’t mention God, then they didn’t make a link to God’s creation of anything. Adam Karaba (Assistant Professor, Department of Organic Technology, UCT Prague) @KarabaAdam wrote: I really dont like when anybody forces his faith into science, or issue his faith as a science. There is no place for such things in the science. It is not rational even ethic.…

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