Model Organisms

RNA-mediated physics, chemistry, and molecular epigenetics (4)

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Femtosecond structural dynamics drives the trans/cis isomerization in photoactive yellow protein 5/6/16 Summary excerpt: Visualizing a response to light Many biological processes depend on detecting and responding to light. The response is often mediated by a structural change in a protein that begins when absorption of a photon causes isomerization of a chromophore bound to … RNA-mediated physics, chemistry, and molecular epigenetics (4)

RNA-mediated physics, chemistry, and molecular epigenetics (3)

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Microtargeting cancer metabolism: opening new therapeutic windows based on lipid metabolism reported as: Using microRNAs to target cancer cells By Dawn Hayward Conclusion:  MicroRNAs stand out from conventional gene-therapy-based approaches and have a niche in lipid metabolism. They can be designed specifically to target a gene and serve as modulators rather than on/off switches. Increased … RNA-mediated physics, chemistry, and molecular epigenetics (3)

RNA-mediated physics, chemistry, and molecular epigenetics (2)

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9/16/15 This is an excellent introduction to speculation about how quantum mechanics might be linked from physics and chemistry to the conserved molecular mechanisms of epigenetically-effected biologically-based RNA-mediated cause and effect, which all serious scientists already know must link angstroms to ecosystems via the innate immune system, the physiology of reproduction, and supercoiled DNA. The … RNA-mediated physics, chemistry, and molecular epigenetics (2)

RNA-mediated physics, chemistry, and molecular epigenetics

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RNA-mediated physics, chemistry, and molecular epigenetics Genetics and Genomics May 11-12, 2016 Published on 3 May 2016  See the full size poster displayed on Figshare.com Abstract: Olfaction and the innate immune system link energy as information from the epigenetic landscape to the physical landscape of supercoiled DNA. The sun’s biological energy is the source of … RNA-mediated physics, chemistry, and molecular epigenetics

Wasted Templeton Funding (4)

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Does the “Extended Synthesis” Replace or Not Replace Neo-Darwinism? — What Has Templeton Funded? Excerpt: Gerd Müller and Kevin Laland are both part of the Templeton-funded ES project. But while Müller is adamant that ES replaces neo-Darwinism, Laland is firm that ES does not replace neo-Darwinism. My comment:  Templeton is funding another attempt to place everything … Wasted Templeton Funding (4)

MicroRNAs and/or QTLs: Who buried what?

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Making precision medicine a reality: Genomics researchers unveil road map to disease origin Excerpt: This study highlights the significance of mechanistic similarities for uncovering additional interacting downstream effectors of intergenic SNPs… My comment: Use of the term QTL may limit the understanding of how energy-dependent cell type differentiation occurs and how virus-driven energy theft is … MicroRNAs and/or QTLs: Who buried what?

Wasted Templeton Funding (3)

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See also: Wasted Templeton Funding (2) Templeton grant funds evolution rethink Excerpt: …parents can influence offspring not just through their DNA but by passing on the microorganisms they host or by transmitting epigenetic marks to subsequent generations. “Innovation may be a developmental response that becomes stabilized through genetic changes,” explains Armin Moczek, an evolutionary developmental … Wasted Templeton Funding (3)

Wasted Templeton Funding (2)

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See also: Wasted Templeton Funding (1) Templeton grant funds evolution rethink Excerpt: The extended evolutionary synthesis is a term coined in 2007 to imply that the preeminent current evolutionary theory, the so-called modern synthesis, needed to broaden its focus because it concentrated too much on the role of genes in evolution and lacked adequate incorporation … Wasted Templeton Funding (2)

Wasted Templeton Funding (1)

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The Randomness Project “…the structure of the program is designed to foster collaboration and build community between scholars, with the end of expanding the range and integration of their work:” My comment: The project and program failed to include any accurate representations of what is known about how RNA-mediated amino acid substitutions link ecological variation … Wasted Templeton Funding (1)