Model Organisms

EDAR V370A and sympatric speciation

May 3, 2018
James Kohl
Adaptations, Diseases & Disorders, Ecology, Model Organisms, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity, Variations
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Nick Lane and others like him refuse to reappraise their human mitochondrial DNA recombination dogma. All serious scientists know where the energy for recombination comes from. But, in his latest video clip, he touts the same unsubstantiated theoretical pseudoscientific nonsense. See the: Aeon Video: Life on earth – from mushrooms to humans and everything in between – seems enormously diverse. At the cellular level, however, almost all complex lifeforms are surprisingly similar. Why life is this way, though, remains mysterious.…

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Ecological Adaptations vs the Randomness of Evolution (2)

May 1, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, microRNA editing, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations
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Summary: See for comparison: Make ‘Em Resistant to Viruses In the new proposal — which Science says was released in advance of a meeting today — GP-write leaders say “ultrasafe” cells could be developed by making some 400,000 changes to the human genome. A Fast One–Step Digestion of DNA or RNA for Global Detection and Characterization of Nucleotide Modifications (link opens pdf) Product information: The Nucleoside Digestion Mix is an optimized mixture of enzymes that provides a convenient one-step method…

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Ecological Adaptations vs the Randomness of Evolution

May 1, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, RNA Directed, RNA editing, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Variations
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Summary: Ecological variation is linked to ecological adaptations in all living genera via the creation of microRNAs and the sense of smell. Odor Perception on the Two Sides of the Brain: Consistency Despite Randomness Highlights •A random model predicts observed preservation of correlations in piriform responses •The model supports consistent agreement about odor quality among individuals The model fails to explain how the energy-dependent creation of microRNAs links pattern recognition to the creation of pre-mRNAs and biophysically constrained viral latency.…

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Virus-driven cystinosis

May 1, 2018
James Kohl
Adaptations, base editing, Cytosis, Diseases & Disorders, Ecology, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, RNA Directed, RNA editing, RNA interference, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
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A friend asked about nephropathic cystinosis, which is a disease caused by the virus-driven theft of quantized energy. All serious scientists have linked viruses from the degradation of messenger RNA to mutations and all pathology. Nephropathic cystinosis (NC) is the most frequent cause of Fanconi syndrome (FS) in young children. It will be linked from the virus-driven degradation of messenger RNA to azoospermia and/or progressive neuromuscular degeneration via the conserved molecular mechanisms of RNA-mediated cell type differentiation compared to mechanisms…

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Environmental selection is natural selection (5)

April 30, 2018
James Kohl
Adaptations, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Subatomic
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Summary: Atheistic Chinese Communists realize that vaccinations cannot protect them. Their attempts to develop a universal vaccine have failed. Bill Gates promotes vaccinations, which led us to the brink of the next pandemic. Vaccines prevent ecological adaptations in some cell types. Does Bill Gates, a non-scientist, think that people from God-fearing non-communist countries can do better than the atheistic Communists? Bill Gates calls on U.S. to lead fight against a pandemic that could kill 33 million Gates and his wife,…

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Environmental selection is natural selection (4)

April 30, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Model Organisms, Physics, Subatomic
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Conclusion: Only biologically uninformed science idiots still believe in the pseudoscientific nonsense of neo-Darwinian evolution. VISUALIZING APOPTOSIS AS IT HAPPENS Apoptosis is a highly regulated and critical homeostatic process in multicellular organisms. Biologically uninformed theorists have claimed the conserved molecular mechanisms of energy-dependent apoptosis in multicelluar organisms arose after energy emerged. Aberrations in this form of energy-dependent programmed cell death have been linked from the virus-driven theft of quantized energy to all pathology. That helps to explain why biologically uninformed…

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Plenty of Room at the Bottom

Environmental selection is natural selection (2)

April 26, 2018
James Kohl
Adaptations, base editing, biophotonics, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
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I believe that if you put enough biologically uniformed theorists in the same room, they will invent more theories to support the pseudoscientific nonsense they have touted in the past. See for example: Environmental selection during the last ice age on the mother-to-infant transmission of vitamin D and fatty acids through breast milk Acknowledgments The synthesis presented here is a product of the American Association for the Advancement of Science’s 2017 annual meeting, as the ideas came together in the…

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Environmental selection is natural selection

April 26, 2018
James Kohl
Adaptations, base editing, biophotonics, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, Nutrigenomics, RNA Directed, RNA-directed DNA methylation, RNA–Mediated Epigenetic Heredity, Variations
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Environmental selection during the last ice age on the mother-to-infant transmission of vitamin D and fatty acids through breast milk was published on April 23, 2018 The ectodysplasin A receptor (EDAR) gene has a range of pleiotropic effects, including sweat gland density, incisor shoveling, and mammary gland ductal branching. The frequency of the human-specific EDAR V370A allele appears to be uniquely elevated in North and East Asian and New World populations due to a bout of positive selection likely to…

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MicroRNA-mediated denuclearization (3)

April 24, 2018
James Kohl
biophotonics, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Physics, RNA–Mediated Epigenetic Heredity, Subatomic
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Directing solar photons to sustainably meet food, energy, and water needs (2017) They propose that the anti-entropic energy of sunlight be linked from the creation of differences in the energy of photons to the biogenesis of microRNAs. What is known about the creation of energy and biophotonics may be used to maximize food growth, maximize the supply of renewable energy and to maximize the supply of water. The acronym for food, energy and water supplies is FEW. They present what…

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MicroRNA-mediated denuclearization (2)

April 24, 2018
James Kohl
Adaptations, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, microRNA editing, Model Organisms, Physics, RNA Directed, RNA editing, RNA interference, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity
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Summary: The virus-driven theft of quantized energy creates a cellular environment that promotes the survival and self-proliferation of viruses by encoding viral miRNAs or miRNA-like molecules. The viral miRNAs or miRNA-like molecules target different types of host cells. The sun’s anti-entropic virucidal energy biophysically constrains viral latency in the context of global control of human ES cell differentiation via circRNAs derived from lncRNAs. That fact refutes all neo-Darwinian gene-centric pseudoscientific nonsense. That fact also attests to the link from Chinese…

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