Pharmacogenomics

MicroRNA-mediated population control (4)

See first: MicroRNA-mediated population control (3) …nearly 125,000 indexed published works link peptide synthesis at the origin of life to visualizing a protonated RNA state that modulates microRNA-21 maturation to biophysically constrained viral latency and healthy longevity across kingdoms from microbes to mammals. See: microRNA There are now more than 125,000 indexed published works. The link from God’s Creation of energy-as-information to pH-dependent biophysically constrained viral latency and healthy longevity across kingdoms can be compared in the context of Characteristics…

Read More

MicroRNA-mediated population control (1)

Your expectations and hope alter your chances of recovery. WHO wants you to give up hope and accept synthetic mRNA vaccines to prevent your recovery by causing more virus-driven diseases, which will  not help to end the SARS-CoV-2 pandemic. RNA interference, the 2002 “breakthrough of the year” will end the SARS-CoV-2 pandemic. In 2002, on the heels of the discovery that RNA interference existed in human cells, the usually reserved journal Science proclaimed RNAi the “breakthrough of the year.” Breakthrough…

Read More

microRNA-mediated replication cycles (10)

See first: microRNA-mediated replication cycles (9) Conclusion from Guenther Witzany What is Life? 3/18/20 …new nucleotide sequences now appear to have originated from social agents such as viruses, their parasitic relatives, and related RNA networks, not from errors. A new definition of life must integrate the current empirical knowledge about interactions between cells, viruses, and RNA networks to provide a better explanatory power than the twentieth century narrative. The twentieth century narrative led to curated news reports that favored stupid…

Read More

microRNA-mediated replication cycles (9)

See first: microRNA-mediated replication cycles (8) Rotavirus research: 2014-2020 7/2/21 A temperature sensitive mutant… in the triplet encoding amino acid 138 of VP1 (L138P)…was separately expressed as a… protein, shown to interact with viroplasm-like particles (VLPs) in uninfected cells and to synthesize RNA in vitro…” My summary: The rotavirus steals the energy required for the ATP-dependent synthesis of RNA, which typically biophysically constrains viral latency across kingdoms. Contextual constraints occur via light-activated carbon fixation, oxidative phosphorylation and RNA interference (RNAi).…

Read More

microRNA-mediated replication cycles (8)

In 365 days, after celebration of independence from public health fascism on Independence Day 2022 in the USA, Guenther Witzany, co-author of Infectious Thoughts: Discovering Biology as a Social Science will end the pseudoscientific nonsense about beneficial mutations and evolution across billions to millions of years via his efforts to organize and to present during this conference. How Evolution Learnt to Learn 7/6/22 – 7/9/22 Representations of the solar analemma, the Mobius strip, examples of infinity, and microRNA-mediated replication cycles…

Read More

Creationism, Communism and Corruption (1)

The Chinese Communist Party (CCP) consistently failed to address facts that link the National Microbiome Initiative to the Precision Medicine Initiative via what people eat and what is known to all intelligent serious scientists about the microRNA-mediated pheromone-regulated genetic processes of reproduction. See for instance more than 113,000 indexed published works that mention “microRNA.” See for example: Multiple microRNAs regulate tacrolimus metabolism through CYP3A5 12/18/20 MicroRNAs are novel regulators of tacrolimus metabolism and the… …CYP3A5 gene polymorphism accounts for the…

Read More

Expert 13 (1)

12 Experts Questioning the Coronavirus Panic 3/19/20 President Donald J. Trump is expert 13 in the context of the fact that differential expression of cell types requires biophysically constrained viral latency. That fact became perfectly clear with the experimental evidence presented in  SARS-CoV-2 RNA reverse-transcribed and integrated into the human genome 12/13/20 The researchers: …investigated the possibility that SARS-CoV-2 RNAs can be reverse-transcribed and integrated into the human genome, and that transcription of the integrated sequences might account for PCR-positive…

Read More

Protonated RNA interference vs stupid theories (7)

See first: Protonated RNA interference vs stupid theories (6) Watch mask-wearing fools dictate that you become more like them before they mandate use of an mRNA vaccine to prevent what has been prevented by food energy and pheromone-regulated genetic processes during the past 5-10,000 years of energy-dependent ecological adaptations. The energy-dependent ecological adaptations were reported in the context of gene-centric theories. See: Gene experts claim they identified human genes that can protect against Covid-19 11/20/20 …current treatments for SARS-CoV-2 infection…

Read More

The microRNA-mediated fight against COVID-19 (1)

History (1) Nutrient-dependent/pheromone-controlled adaptive evolution: a model (2013) …the epigenetic ‘tweaking’ of the immense gene networks that occurs via exposure to nutrient chemicals and pheromones can now be modeled in the context of the microRNA/messenger RNA balance, receptor-mediated intracellular signaling, and the stochastic gene expression required for nutrient-dependent pheromone-controlled adaptive evolution. History (2) Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems (2014 unpublished) This atoms to ecosystems model of ecological adaptations links nutrient-dependent epigenetic effects on base pairs and amino…

Read More

Vaccines do not control pandemics (1)

See: Emergence of Human G2P[4] Rotaviruses in the Post-vaccination Era in South Korea: Footprints of Multiple Interspecies Re-assortment Events 4/16/18 Compared to the G2 RotaTeq vaccine strain, 17-24 amino acid changes, specifically A87T, D96N, S213D, and S242N substitutions in G2 epitopes, were observed. Amino acid changes control pandemics. Congo: MSF Ebola vaccination begins 5/30/18 The Ebola vaccine (rVSVDG-ZEBOV-GP) is being used as part of the overall strategy to control the Ebola outbreak. There was no indication that the vaccine strategy…

Read More