replication timing

Codon optimality vs systemic fraud (4)

A good model predicts. See: From Fertilization to Adult Sexual Behavior (1996). In our section on molecular epigenetics we predicted that A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins 6/16/22 would be linked to food energy and pheromone-regulated genetic processes of reproduction across kingdoms. On 6/23/22, that fact was placed back into the context of stupid theories. See: Abracadabra, One Becomes Two: The Importance of Context in Viral −1 Programmed Ribosomal Frameshifting  Yeast and potentially mammalian cells,…

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Codon optimality vs systemic fraud (2)

See first: Codon optimality vs systemic fraud (1) Researchers identified over 5,500 new viruses in the ocean, including a missing link in viral evolution 4/8/22 and Ocean water samples yield treasure trove of RNA virus data 4/8/22 attest to facts about the Footprints of a Singular 22-Nucleotide RNA Ring at the Origin of Life 4/25/20 that link God’s ATP-dependent Creation of RNA from RNA-peptide interactions at the origin of life to the Mapping and characterization of structural variation in 17,795…

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Codon optimality vs systemic fraud (1)

Two summaries of neo-Darwinian evolutionary theory: Amino acid composition of proteins varies substantially between taxa and, thus, can evolve. …yeast receptors trigger activation of heterotrimeric G proteins just as mammalian receptors do, this conserved signaling pathway must have been present in the common ancestor of yeast and humans. Unless you are a biologically uninformed theorist, see first Epistemic corruption (10) Watch for my next 10-part series on Codon optimality vs systemic fraud. I will link it to the fraudulent representations…

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Epistemic corruption (10)

Biosynthesis of cyanobacterin, a paradigm for furanolide core structure assembly 5/26/22 Full functional evaluation of the recombinant key enzymes in vivo and in vitro, individually and in concert, provided in-depth mechanistic insights into a streamlined C–C bond-forming cascade that involves installation of compatible reactivity at seemingly unreactive Cα positions of amino acid precursors. Our work extends the biosynthetic and biocatalytic toolbox for γ-butyrolactone formation, provides a general paradigm for furanolide biosynthesis and sets the stage for their targeted discovery, biosynthetic…

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Epistemic corruption (9)

A prebiotically plausible scenario of an RNA–peptide world was reported in Science Magazine by Robert F. Service. See: How life could have arisen on an ‘RNA world’ 5/11/22 New evidence suggests RNA and peptides may have helped build each other on early Earth Researchers who study the origin of life have long considered RNA the central player because it can both carry genetic information and catalyze necessary chemical reactions. It was likely present on our planet before life evolved. But…

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Epistemic corruption (7)

NYU may hire biologist pushed out of MIT, Whitehead for sexual misconduct 4/25/22 “Civility Rules.” “A mob feels compelled to stridently ‘cancel’ someone with different thoughts, or to baselessly attack an individual in ways that can be difficult to disprove,” he wrote. “This is tolerated in academia, where nameless accusers can disparage a colleague’s science and life’s work, even when their claims are unfounded.” Grossman declined to comment further. Eric Lander, former science advisor to Joe Biden, became a victim…

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Epistemic corruption (6)

Summary: The rapid pace of experimental evidence linked to Selective MicroRNA-Offset RNA Expression in Human Embryonic Stem Cells 3/30/15 can be compared to the nonsense touted by neo-Darwinian theorists published as Shining Light on the Evolution of Photosynthesis 12/1/03 Photosynthetic bacteria and eukaryotes collect light energy for photosynthesis in structures called light-harvesting antenna complexes. Unless the light-harvesting complexes automagically created themselves, the facts about God’s Creation of sunlight link light-activated carbon fixation in cyanobacteria to pH-dependent microRNA-mediated protein folding chemistry,…

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Epistemic corruption (5)

This is a false claim Bacterial species rarely work together  5/5/22 See this placard from the US Department of the Interior’s National Park Service for comparison: Cyanobacteria were once called blue-green algae. Light-activated carbon fixation in cyanobacteria links their color from microRNA-mediated protein folding chemistry to protection from the virus-driven degradation of messenger RNA (mRNA). The protection of organized genomes from viruses has been linked to constraints on all virus-driven pathology across kingdoms via this patent for RNA interference, which…

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Epistemic corruption (4)

Link opens the CDC’s page on: Cyanobacteria, also called blue-green algae, are microscopic organisms found naturally in all types of water. These single-celled organisms live in fresh, brackish (combined salt and fresh water), and marine water. These organisms use sunlight to make their own food. Acting NIH Director Admits Appearance Of Conflict Of Interest In Secret Royalty Payments To Fauci, Scientists 5/11/22 Collins received 14 payments, Fauci received 23 payments… There is no better example of this than the third-party…

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MicroRNA-mediated existential threats (9)

See: MicroRNA-mediated existential threats (8) Confront anyone who tells you that Amino acid composition of proteins varies substantially between taxa and, thus, can evolve. Living with the Neanderthals  8/14/03 Through one of his characters, Bear pleads for biologists to write clearly: “Don’t they realize how important it is to get the word out to everybody?” Pit your claims about synthetic mRNA booster vaccines against :facts published as “Visualizing a protonated RNA state that modulates microRNA-21 maturation” See  mRNA vaccines are useless…

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