RNA-directed DNA methylation

God’s microRNA-mediated Creation of genotypes (5)

Summary: Energy-dependent changes in single nucleotide polymorphisms (SNPs) in microribonucleic acids (microRNAs/miRNAs) were linked from femotosecond blasts of UV light to DNA repair via an extremely sensitive assay for the label-free optical detection and suppression of interfering effects caused by non-specific binding. Interactions in Augmented and Mixed Reality: An Overview 9/20/21 (This article belongs to the Special Issue Extended Reality: From Theory to Applications) All interactions are energy-dependent and microRNA-mediated. ~250 newly indexed articles attest to that fact, which is…

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God’s microRNA-mediated Creation of genotypes (2)

More than 127,000 indexed published works link God’s energy-dependent Creation of microRNAs to all biodiversity via energy-dependent microRNA-mediated DNA supercoiling . See: microRNA See first: God’s microRNA-mediated Creation of genotypes (1) See also: MiR-125b regulates the differentiation of hair follicles in Fine-wool Sheep and Cashmere goats by targeting MXD4 and FGFR2 9/6/21 If you can’t link this to chromosomal rearrangements and sympatric speciation in species from flies to labradoodles, you haven’t played the STEM toy for ages 14+ “Genotype.” One…

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God’s microRNA-mediated Creation of genotypes (1)

See first: Natural selection for adaptation (10) DNA Logic Circuits for Multiple Tumor Cells Identification Using Intracellular MicroRNA Molecular Bispecific Recognition  9/5/21 The bispecific intracellular miRNA controllable DNA circuit…easily extends to various cell type discrimination by adjusting the [energy-dependent biophysically constrained Creation of] miRNA species… When Fauci claimed it was molecularly impossible to engineer SARS-CoV-2 in the Wuhan lab, the extent of his lies became clear. The fact that he lied before Congress is now clearer. See: Learning noncoding RNA…

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Natural selection for adaptation (10)

See: Ignoring light-activated microRNA biogenesis 10/16/18, and compare our section on pre-mRNAs and molecular epigenetics in: From Fertilization to Adult Sexual Behavior (1996) to MicroRNAs buffer genetic variation at specific temperatures during embryonic development 10/16/18, which was previously published sans mention of microRNAs as Temporal development of Drosophila embryos is highly robust across a wide temperature range 7/11/18 Changing the term from pre-mRNAs to microRNAs obfuscated food energy-dependent pheromone-regulated genetic processes of cause and effect, but see ~127,000 indexed publications…

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Natural selection for adaptation (8)

Facts about natural selection for adaptation can be compared to theories of Evolution by Gene Duplication (1970) The creation of metazoans, vertebrates and finally mammals from unicellular organisms… required the creation of new gene loci with previously nonexistent functions. The persistent theories of evolution by gene duplication can be compared to facts natural selection for adaptation in the context of God’s Creation of subatomic particles, such as protons and the ATP-dependent creation of RNA, which was required to link the…

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Natural selection for adaptation (7)

Microbial signatures in the lower airways of mechanically ventilated COVID-19 patients associated with poor clinical outcome 8/31/21 was reported as: High virus count in the lungs drives COVID-19 deaths 8/31/21 …the study revealed that those who died had on average 50 percent lower production of a type of immune chemical that targets the coronavirus compared with the COVID-19 patients who survived the illness. These customized proteins are part of the body’s adaptive immune system, a subset of cells and chemicals…

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Natural selection for adaptation (5)

See first: Natural selection for adaptation (4) If you have not yet linked God’s Creation of energy-as-information from the pH-dependent physiology of reproduction to biophysically constrained viral latency and all phenotypes, start with Regulation of MicroRNAs 8/26/21. For comparison, Charles Darwin invented his theory based on no ability to observe biophysically constrained energy-dependent top-down causation at the molecular level. He bred pigeons, which led him to focus on morphology and link the food that finches ate to beak morphology because…

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Natural selection for adaptation (4)

See first: Natural selection for adaptation (3) See also: “pericentromeric satellite RNA expression” Did you mean “pericentromeric satellite dna expression” No. I am not a stupid gene-centric theorist. I am a Creationist who knows how energy-dependent supercoiled DNA is Created. For instance, light-activated microRNA-mediated “Biogenesis is regulated by many checkpoints at every step, primarily at the transcriptional level, in the nucleus, cytoplasm, with RNA regulation, RISC loading, miRNA strand selection, RNA methylation/uridylation, and turnover rate.” If you have not yet…

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Natural selection for adaptation (2)

See first: Natural selection for adaptation (1) It’s been 20 days since biologically uninformed science idiots reported everything known to intelligent serious scientists about natural selection for biophysically constrained viral latency and ecologically adapted phenotypes in the context of cryptic transmission. See: Altered chromatin states drive cryptic transcription in aging mammalian stem cells 8/2/21 This nonsense was reported on 8/3/21 as Aging Cells May Lose Control of Where an mRNA Sequence Starts The cell’s machinery ‘reads’ DNA sequences in sets…

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Natural selection for adaptation (1)

My August 12, 2021 tweet made more than 34,000 impressions. That fact was reported on August 18, 2021 after I publicly complained about the delay in making it my “Top Tweet” for the month. My complaint was based on the fact that nearly 126,000 citations to published works mention microRNAs. Each of them attests to facts about natural selection for energy-dependent codon optimality. All intelligent serious scientists know that codon optimality biophysically constrains viral latency and healthy longevity across kingdoms…

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