RNA-directed DNA methylation

Codon optimality vs systemic fraud (4)

A good model predicts. See: From Fertilization to Adult Sexual Behavior (1996). In our section on molecular epigenetics we predicted that A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins 6/16/22 would be linked to food energy and pheromone-regulated genetic processes of reproduction across kingdoms. On 6/23/22, that fact was placed back into the context of stupid theories. See: Abracadabra, One Becomes Two: The Importance of Context in Viral −1 Programmed Ribosomal Frameshifting  Yeast and potentially mammalian cells,…

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Codon optimality vs systemic fraud (2)

See first: Codon optimality vs systemic fraud (1) Researchers identified over 5,500 new viruses in the ocean, including a missing link in viral evolution 4/8/22 and Ocean water samples yield treasure trove of RNA virus data 4/8/22 attest to facts about the Footprints of a Singular 22-Nucleotide RNA Ring at the Origin of Life 4/25/20 that link God’s ATP-dependent Creation of RNA from RNA-peptide interactions at the origin of life to the Mapping and characterization of structural variation in 17,795…

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Codon optimality vs systemic fraud (1)

Two summaries of neo-Darwinian evolutionary theory: Amino acid composition of proteins varies substantially between taxa and, thus, can evolve. …yeast receptors trigger activation of heterotrimeric G proteins just as mammalian receptors do, this conserved signaling pathway must have been present in the common ancestor of yeast and humans. Unless you are a biologically uninformed theorist, see first Epistemic corruption (10) Watch for my next 10-part series on Codon optimality vs systemic fraud. I will link it to the fraudulent representations…

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Epistemic corruption (10)

Biosynthesis of cyanobacterin, a paradigm for furanolide core structure assembly 5/26/22 Full functional evaluation of the recombinant key enzymes in vivo and in vitro, individually and in concert, provided in-depth mechanistic insights into a streamlined C–C bond-forming cascade that involves installation of compatible reactivity at seemingly unreactive Cα positions of amino acid precursors. Our work extends the biosynthetic and biocatalytic toolbox for γ-butyrolactone formation, provides a general paradigm for furanolide biosynthesis and sets the stage for their targeted discovery, biosynthetic…

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Epistemic corruption (7)

NYU may hire biologist pushed out of MIT, Whitehead for sexual misconduct 4/25/22 “Civility Rules.” “A mob feels compelled to stridently ‘cancel’ someone with different thoughts, or to baselessly attack an individual in ways that can be difficult to disprove,” he wrote. “This is tolerated in academia, where nameless accusers can disparage a colleague’s science and life’s work, even when their claims are unfounded.” Grossman declined to comment further. Eric Lander, former science advisor to Joe Biden, became a victim…

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Epistemic corruption (6)

Summary: The rapid pace of experimental evidence linked to Selective MicroRNA-Offset RNA Expression in Human Embryonic Stem Cells 3/30/15 can be compared to the nonsense touted by neo-Darwinian theorists published as Shining Light on the Evolution of Photosynthesis 12/1/03 Photosynthetic bacteria and eukaryotes collect light energy for photosynthesis in structures called light-harvesting antenna complexes. Unless the light-harvesting complexes automagically created themselves, the facts about God’s Creation of sunlight link light-activated carbon fixation in cyanobacteria to pH-dependent microRNA-mediated protein folding chemistry,…

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Epistemic corruption (5)

This is a false claim Bacterial species rarely work together  5/5/22 See this placard from the US Department of the Interior’s National Park Service for comparison: Cyanobacteria were once called blue-green algae. Light-activated carbon fixation in cyanobacteria links their color from microRNA-mediated protein folding chemistry to protection from the virus-driven degradation of messenger RNA (mRNA). The protection of organized genomes from viruses has been linked to constraints on all virus-driven pathology across kingdoms via this patent for RNA interference, which…

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Epistemic corruption (1)

Sunlight is the best disinfectant. That claim was echoed by Elon Musk on 5/3/22. If he stops the social media censorship of facts on Twitter, the epistemic corruption may end. Epistemic Corruption, the Pharmaceutical Industry, and the Body of Medical Science 3/8/21 It is not just that there is a body of medical science perverted by industry largesse. Instead, much of the corruption of medical science via the pharmaceutical industry happens through grafting activities: Pharmaceutical companies do their own research…

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MicroRNA-mediated existential threats (4)

See first:  MicroRNA-mediated existential threats (3) On 4/19/22 I posed this question on Twitter. Why do people believe stupid theories about the evolution of amino acid composition in proteins, which requires them to ignore everything known to intelligent serious scientists about how SARS-CoV-2 synthetic mRNA vaccinations altered biophysically constrained viral endemicity? 4/19/22 How can it not be perfectly clear that stupid theories about the evolution of amino acid composition in proteins ignore everything known to all intelligent serious scientists about…

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MicroRNA-mediated existential threats (3)

“Footprints of Multiple Interspecies Re-assortment Events” (4/16/18) link the failed efficacy of COVID19 vaccines,  to the microRNA-mediated future of humanity via patents held for therapeutic solutions by Thomas E. Eichim et al., in the context of former President Trump’s claim on 4/23/20 about light-activated protein folding chemistry and Characteristics of the MicroRNA Expression Profile of Exosomes Released by Vero Cells Infected with Porcine Epidemic Diarrhea Virus  (indexed on 4/23/22) Details: Exosomes… contain regulated microRNA (miRNA), allowing them to function in…

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