RNA interference

Reporting new scientific truths is not allowed in the USA (2)

Summary: Genetic mutations do not drive evolution.  Energy-dependent RNA-mediated fixation of amino acid substitutions links the physiology of reproduction to biophysically constrained viral latency. With minimal effort, you can peruse the science news each day to see how many pseudoscientists report their findings outside the context of food energy-dependent pheromone-controlled biophysically constrained RNA-mediated cell type differentiation. See for example: Type 2 diabetes has hepatic origins The researchers are now working on identifying the endogenous ligand produced by the body, or…

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Light activated error-free DNA repair (3)

The vibrational theory of olfaction for the win …he and his co-authors delve into more of the specifics of olfactory receptors, including particular amino acid motifs, metal binding capacities, and disulphide bridge redox status. It turns out that amino acid side chains alone frequently pull off some rather interesting electron transfer effects without the need for fancy co-enzymes or prosthetic groups. See for an example of what one enzyme can do: See also this example of how the energy-dependent creation…

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Light-activated error free DNA repair (2)

Summary: In the diagram and diatribes that accompany claims about de novo changes in electrons and the production of nucleotides, the amount of pseudoscientific nonsense becomes perfectly clear. Pseudoscientists start with energy-dependent changes but call the changes de novo changes in electrons. That allows the pseudoscientists to dismiss any facts about how the creation of energy must be linked to the creation of enzymes. The creation of enzymes does not automagically occur and the creation of all biodiversity must occur…

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Schrodinger’s answer to Schrodinger’s question

There is no such thing as de novo control of electrons or self-assembly. Answering Schrödinger’s question: A free-energy formulation The free-energy principle (FEP) is a formal model of neuronal processes that is widely recognised in neuroscience as a unifying theory of the brain and biobehaviour. More recently, however, it has been extended beyond the brain to explain the dynamics of living systems, and their unique capacity to avoid decay. They don’t understand the question that Schrodinger answered. He linked the…

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A null mutation and healthy longevity?

Summary: Food odors and pheromones biophysically constrain all pathology in species from microbes to humans. What kind of biologically uninformed science idiot leaves out everything known to serious scientists about the virus-driven degradation of messenger RNA and tells others they must falsify the neutral null theory that led to claims about a biophysically constrained beneficial “null mutation” in the Amish population of Berne, Indiana? Glutamylation Regulates Transport, Specializes Function, and Sculpts the Structure of Cilia Reported as: How to Control…

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Light-activated error free DNA repair

Summary: The same set of microRNAs controls expression of the genes for rate-limiting enzymes, which control differences in the hormone production of different hormones in insects and crustaceans. That fact led to this claim in: The secret to safe DNA repair. …if you don’t have this enzyme, then this error-free repair is stopped. You can’t do it. If you can’t do the error-free repair, among other things that happen is that you expect these cells to be cancer prone. The…

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Epigenetic facts vs variable recombination theories

6/14/13 Nutrient-dependent/pheromone-controlled adaptive evolution: a model ….the model represented here is consistent with what is known about the epigenetic effects of ecologically important nutrients and pheromones on the adaptively evolved behavior of species from microbes to man. Minimally, this model can be compared to any other factual representations of epigenesis and epistasis for determination of the best scientific ‘fit’. 7/25/13 Jay R. Feierman: Variation is not nutrient availability and the something that is doing the selecting is not the individual…

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From base editing to RNA editing (4)

Summary: To claim evolution, Koonin must link food energy from the pheromone-controlled physiology of reproduction to fixation of a beneficial mutation in the organized genome of one species that evolved into another species. Search Results for “base editing” = 82 blog posts starting with Cell-type differentiation on February 7, 2014 Search Results for “RNA editing” = 95 blog posts starting with In theory, or supported by experimental evidence? October 22, 2014 See for comparison PubMed: “base editing” (33 citations) and…

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From base editing to RNA editing (3)

Summary: Claims about spontaneous deamination fail to link energy-dependent changes from base editing to RNA-mediated DNA repair of damage caused by the virus-driven degradation of messenger RNA. Highly efficient RNA-guided base editing in mouse embryos 27 February 2017 They reported the use of RNA-programmable deaminases to make various animal models with single amino-acid substitutions.They linked the single amino acid substitutions from the correction of nonsense mutations in the future to the correction of genetic defects in human embryos. Reported as:…

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Loss of energy as information (1)

Summary: Koonin claims that the theories of population geneticists have replaced what he calls the just-so stories of adaptationists with testable predictions. He claims that serious scientists should attempt to falsify the ridiculous theories touted by people like him, so that the ongoing use of ridiculous mathematical models can improve our understanding of evolution. I think Koonin may be attempting to address the concerns brought forward after another biologically uninformed science idiot claimed that my refutation of neo-Darwinian pseudoscientific nonsense…

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  • What Darwin proved: there’s no such thing as a species
    GENETICS As Animals Mingle, a Baffling Genetic Barrier A short stretch of DNA is challenging what it means to be a species. By: Emily Singer August 5, 2014 Excerpt: “Scientists have dubbed such regions of the genome “islands of speciation.” The persistence of such islands is a phenomenon that has been observed in a variety of […]
  • Randomness and Divine Providence
    A Q&A on randomness and God’s providence …the main goal is to really put together a collection of scholarly studies of these issues: physicists, biologists, […]
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