RNA interference

Anti-entropic sunlight: Schrödinger’s Creationist Secret? (2)

  Arabidopsis mRNA decay landscape arises from specialized RNA decay substrates, decapping-mediated feedback, and redundancy The decay of mRNA plays a vital role in modulating mRNA abundance, which, in turn, influences cellular and organismal processes. In plants and metazoans, three distinct pathways carry out the decay of most cytoplasmic mRNAs: The mRNA decapping complex, which requires the scaffold protein VARICOSE (VCS), removes a protective 5′ cap, allowing for 5′ to 3′ decay via EXORIBONUCLEASE4 (XRN4, XRN1 in metazoans and yeast),…

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The MicroRNAome Strikes Back: A Sokalian hoax (9)

Summary: Darwin’s “conditions of life” link the creation of sunlight from the creation of ATP to the creation of microRNAs and RNA-mediated cell type differentiation in the context of biophysically constrained viral latency. There is no magical creation of an RNA force field or protein force field that could be used to link the magic of evolution to biologically-based diversity in species from microbes to humans. RNA force field with accuracy comparable to state-of-the-art protein force fields The complex and…

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BiondVax Universal Flu Vaccine Patent

Summary: …the dream to create an effective universal flu vaccine to ultimately eradicate the flu is placed into the context of claims about changes to the virus. The changes are energy-dependent ecological adaptations. No one claims that the virus mutates or that it evolves. Only biologically uninformed theorists make such ridiculous claims. BiondVax Universal Flu Vaccine Patent Granted in India The patent describes influenza vaccines comprised of multiple copies of several epitopes, such as M-001 which contains nine common and…

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http://nnjournal.net/article/viewFile/2354/1850/10234

The MicroRNAome Strikes Back: A Sokalian hoax (5)

Premise: Sunlight is the quantized energy as information that is required to link endogenous RNA interference to healthy longevity (The energy-dependent creation of microRNAs links the physiology of reproduction from changes in electrons to ecosystems in all living genera via the creation of ATP, RNA, and supercoiled DNA in organized genomes.) Counter claim:  The Quantum Thermodynamics Revolution: Information theory Understanding entropy as a subjective measure allows the universe as a whole to evolve without ever losing information. See, for comparison: On…

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The MicroRNAome Strikes Back: A Sokalian hoax (3)

One way to recognize a Sokalian hoax is to determine whether the claims can be linked from gravity or from the speed of light on contact with water to feedback loops that biophysically constrain viral latency and all biodiversity in all living genera. See: Feedback loops link odor and pheromone signaling with reproduction See for comparison: Chiromagnetic nanoparticles and gels Reported as: Nanoparticle gel controls twisted light with magnetism The trick, the researchers found, was to twist the nanoparticles themselves by coating them…

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https://media.springernature.com/lw900/springer-static/image/art%3A10.1038%2Fs41467-017-02632-8/MediaObjects/41467_2017_2632_Fig6_HTML.jpg

Why Trump won’t meet with some 2017 Nobel Laureates

Excerpt: Others have seen the latest experimental evidence on biophysically constrained energy storage coming, but they have remained relatively silent. This is a deliberate attempt to increase the number of my tweet impressions to more than 80K since Christmas eve, during the same month that ~1000 more articles on microRNA-mediated energy storage were added to the PubMed database. On June 24, 2017,  I joked about the claims of science journalist Philip Ball. His pseudoscientific nonsense about quantum common sensee led to…

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http://nnjournal.net/article/viewFile/2354/1850/10234

A mental health problem at the highest level (2)

Biologically uninformed theorists and so-called science journalists have ignored their own mental health issues and focussed their attention on the mental health of serious scientists. Some of the serious scientists advise the President of the United States in attempts to help him make America great again by draining the political and academic swamps. It is time to examine the personality disorders of theorists and biologically uninformed journalists for comparison to the mental health of serious scientists and the President of…

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http://nnjournal.net/article/viewFile/2354/1850/10234

Diet-driven RNA interference and mental health (1)

The historical record of facts about the transgenerational epigenetic inheritance of RNA-mediated diet-driven mental health must be viewed in the context of the claims made by neo-Darwinian theorists and “Big Bang” cosmologists. They refused to link the creation of the anti-entropic virucidal energy of sunlight on contact with water from the creation of microRNAs to all biodiversity on Earth via the creation of enzymes. They still refuse to acknowledge the fact that the physiology of pheromone-controlled reproduction in species from…

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Autophagy is the antiphage defense strategy (2)

2/15/17 Energy as information and constrained endogenous RNA interference (video) The 6.46 minute-long technical presentation (above) from the Precision Medicine Virtual Conference is difficult to understand.Thus, 10 months later, Nik Willmore asked: 12/24/17 What are your insights into CRISPR and mTOR, for a young audience? I’m not mocking you…yet, Humpty Dumpty. What is the basis of your unifying principle? Vibration? Bohmian morphogenetic fields? Modified Darwin? God? –Nik Willmore @nikwillmore 12/25/17 Replying to @nikwillmore @jhewitt123 God created the anti-entropic virucidal energy of sunlight and…

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Enzyme-constrained interethnic biodiversity (6)

I think that I may be able to finish this series before the end of the month and use my tweets to expose more than 100,000  people to what is known about how the energy-dependent creation of microRNAs prevents all pathology. See for one example of more than 68,000 published works: MicroRNA-22 suppresses cell proliferation, migration and invasion in oral squamous cell carcinoma by targeting NLRP3 For an extensive review of biologically-based biophysically constrained viral latency, see: Enzyme-constrained interethnic biodiversity…

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