RNA–Mediated Epigenetic Heredity

RNAi 2002 to AI 2021 (10)

The 6-part series on Energy-dependent epigenetic translation to mRNA stability that ran here between 5/12/17 and 5/22/17 predictably links facts about energy-dependent microRNA-mediated chromosomal inheritance to the end of all the stupid theories that were touted by Gene Levinson in Rethinking Evolution: The Revolution That’s Hiding in Plain Sight (2021) See first: RNAi 2002 to AI 2021 (8) Light-activated microRNA biogenesis obviously links God’s energy-dependent Creation of the cell wall across kingdoms via: Biogenesis and Mechanisms of miRNA-Mediated Gene Regulation…

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RNAi 2002 to AI 2021 (8)

Prebiotic amino acids bind to and stabilize prebiotic fatty acid membranes 8/12/19 To test whether the inclusion of amino acids addresses this problem, we coupled direct techniques of cryoelectron microscopy and fluorescence microscopy Reported as:  First cells may have emerged because building blocks of proteins stabilized membranes 8/12/19 The stability of membranes is hydrogen-bond (pH) dependent. Nothing known to intelligent serious scientists about top-down causation suggests that stability of cell membranes automagically emerged. See for comparison:  microRNA More than 133,000…

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RNAi 2002 to AI 2021 (7)

I found this claim in an unpublished blog post from 4/14/15 while attempting to update other posts. Most of more than 1600 are missing the focus keyphrase “microRNA” …the control of cellular and organism-wide homeostasis by the epigenetic effects that inhibit viral replication (e.g., proper nutrition and social stress inhibition), might be the best approach to prevent our evolution to another species, or our diet-driven and social stress-driven extinction. See: Epigenetic effects of viruses on cellular homeostasis 10/29/12 Historical perspective:…

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RNAi 2002 to AI 2021 (5)

In case you are a moronic public health fascist, liberal, atheist, or Communist who missed it, start your new year with facts about how to prevent or to effectively treat all virus-driven diseases. See: Footprints of a Singular 22-Nucleotide RNA Ring at the Origin of Life 4/25/20, Visualizing a protonated RNA state that modulates microRNA-21 maturation 10/26/20 and Peptide synthesis at the origin of life 11/13/20. Don’t wait another year to learn how to link energy-dependent biophysically constrained changes in…

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RNAi 2002 to AI 2021 (4)

Happy New Year. Got SARS-Cov-2 or one of its synthetic mRNA vaccine-induced variants yet? SARS-CoV-2 expresses a microRNA-like small RNA able to selectively repress host genes 12/28/21 …we unexpectedly discovered a viral miRNA-like small RNA, named CoV2-miR-O7a (for SARS-CoV-2 miRNA-like ORF7a-derived small RNA). Its abundance ranges from low to moderate as compared to host miRNAs and it associates with Argonaute proteins-core components of the RNA interference pathway. For a historical perspective on the role of microRNA-like small RNAs in viruses,…

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RNAi 2002 to AI 2021 (3)

See first: RNAi 2002 to AI 2021 (2) 12/30/21 The number of intelligent serious scientists who have integrated what is known about the physics, chemistry, and molecular biology of naturally occurring biophysically constrained microRNA-mediated viral endemicity and healthy longevity attests to the fact that most of them have been silenced. Indeed, in response to many of my Facebook Posts, Facebook claims: Independent fact-checkers investigate stories in a journalistic process meant to result in establishing the truth or falsity of the…

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RNAi 2002 to AI 2021 (2)

For more facts that link RNAi to young earth creationism and AI to pseudoscientific nonsense, see: DNA from dirt can offer new view of ancient life 7/12/21 The new study adds to a handful of others to show the power of DNA from ancient soils. No experimental evidence of biophysically constrained energy-dependent top-down creation of soil types exists that extends the dating from Biblical Genesis beyond the past 5-10,000 years. That fact places God’s Creation of energy-as-information into the context…

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RNAi 2002 to AI 2021 (1)

Summary: Intelligent serious scientists have linked energy-dependent RNA interference (RNAi) to all biodiversity on Earth. For comparison, biologically uninformed theorists have nothing but mathematical models and Artificial Intelligence (AI). Human pheromones: integrating neuroendocrinology and ethology  (2001) …the affect of pheromones on our emotions is linked to the effect of pheromones on the hormones of the hypothalamic-pituitary-gonadal axis –an unconscious affect. Based upon a detailed mammalian neuroendocrine model, Kohl [15] proposed that LH is the measurable link between sex and the…

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microRNA-mediated cures (10)

Merry Christmas 2021! Summary: microRNA-mediated cures for all virus-driven pathology have been linked from the 2002 Breakthrough of the Year: Small RNAs (12/19/02) to the 2021 Breakthrough of the year: Protein structures for all (12/16/21) via light-activated carbon fixation and biophysically constrained naturally-attenuated viral endemicity/latency in species from cyanobacteria to humans. As presciently predicted in Biblical Genesis, the physiology of pheromone-regulated genetic processes is required. That fact has been exemplified in at least 3 different patents, all of which attest…

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microRNA-mediated cures (8)

A clear indicator of what is required to end the SARS-CoV-2 pandemic was published as: Host cell entry mediators implicated in the cellular tropism of SARS‑CoV‑2, the pathophysiology of COVID‑19 and the identification of microRNAs that can modulate the expression of these mediators (Review) 12/20/21 The pathophysiology of coronavirus disease 2019 (COVID‑19) is mainly dependent on the underlying mechanisms that mediate the entry of severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) into the host cells of the various human tissues/organs.…

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