RNA–Mediated Epigenetic Heredity

From base editing to RNA editing (4)

Summary: To claim evolution, Koonin must link food energy from the pheromone-controlled physiology of reproduction to fixation of a beneficial mutation in the organized genome of one species that evolved into another species. Search Results for “base editing” = 82 blog posts starting with Cell-type differentiation on February 7, 2014 Search Results for “RNA editing” From base editing to RNA editing (4)

From base editing to RNA editing (3)

Summary: Claims about spontaneous deamination fail to link energy-dependent changes from base editing to RNA-mediated DNA repair of damage caused by the virus-driven degradation of messenger RNA. Highly efficient RNA-guided base editing in mouse embryos 27 February 2017 They reported the use of RNA-programmable deaminases to make various animal models with single amino-acid substitutions.They linked From base editing to RNA editing (3)

From base editing to RNA editing

Base Editing Now Able to Convert Adenine-Thymine to Guanine-Cytosine “Nature conveniently provides us with cytosine deaminase enzymes that operate on DNA,” Liu tells The Scientist. The creation of quantized energy in sunlight links energy as information from electrons to ecosystems via the physiology of reproduction in all living genera. The claim that “Nature” provides us From base editing to RNA editing

Loss of energy as information (1)

Summary: Koonin claims that the theories of population geneticists have replaced what he calls the just-so stories of adaptationists with testable predictions. He claims that serious scientists should attempt to falsify the ridiculous theories touted by people like him, so that the ongoing use of ridiculous mathematical models can improve our understanding of evolution. I Loss of energy as information (1)

Long-term adaptation replaces evolution (3)

Summary: Koonin thinks that serious scientists who have linked the creation of energy to all biodiversity via the physiology of pheromone-controlled reproduction in species from microbes to humans must prove that everything the serious scientists know did not occur randomly after the sun’s anti-entropic virucidal energy emerged from nothing. Other pseudoscientists have taken a step Long-term adaptation replaces evolution (3)

Long-term adaptation replaces evolution (2)

The food energy-dependent “doubling up” on ‘junk DNA’ is biophysically constrained by the physiology of pheromone-controlled reproduction. The metabolism of food to species-specific pheromones links the conserved molecular mechanisms of RNA-mediated cell type differentiation in all individuals of all living genera to healthy longevity via what is known about amino acid substitutions in supercoiled DNA, which Long-term adaptation replaces evolution (2)

Until death: Virus-driven failure of multisensory integration (2)

Lethal virus kills 5 billion people?

Summary: The virus-driven degradation of messenger RNA is clearly linked to frontotemporal dementia (FTD) by altered language, personality, behavior, cognition and motor function. What causes FTD? If the virus-driven degradation of messenger RNA causes all pathology, I would expect to find a link from microRNAs to the pathology and to the effective treatment. The social Until death: Virus-driven failure of multisensory integration (2)

Biophysically constrained intelligence vs human idiocy

Microbes Mind Forum Research on origins, evolution, and syntheses of life How did self-organization and evolution give rise to complex, life-like systems and how can these dynamics inform our futures? How can we move beyond the Tragedy of the Commons as a necessary outcome of evolutionary dynamics to evolve toward sustainable futures, channeled by constraints Biophysically constrained intelligence vs human idiocy