RNA–Mediated Epigenetic Heredity

Photonics in Forensics (1)

February 21, 2022
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News
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Effective 2/20/22, 135,840 results from a search of PubMed for “microRNAs” includes this article: MiRLoc: predicting miRNA subcellular localization by incorporating miRNA-mRNA interactions and mRNA subcellular localization …results show that miRNA functional similarity data can be effectively used to predict miRNA subcellular localization… Intelligent serious scientists know the claim about microRNA-mediated subcellular localization and functional similarity eliminates all the claims made by gene-centric theorists, since the time they started inventing their stupid theories. But wait, there’s more! For a historical…

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microRNA-mediated biodiversity (10)

February 20, 2022
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Neuronal Plasticity, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News
2 Comments

“Barrage of disconnected posts” Sound familiar? Should be like looking in a mirror for you. 2/20/22 @ppchuman, @JikkyKjj, and @B3H3ALTHY are among the anonymous fools, biologically uninformed science idiots, and killer clowns such as @RNAsucks, who failed to link light-activated carbon fixation in cyanobacteria to microRNA-mediated protein folding chemistry and healthy longevity via energy-dependent epigenetic effects on gene sequences and RNA interference (#RNAi), which I detailed in my model. There is no other model of naturally occurring biophysically constrained pH-dependent…

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microRNA-mediated biodiversity (9)

February 20, 2022
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Nutrigenomics, Pharmacogenomics, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News
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microRNA (miR-KT-635) encoded by Cyprinid herpesvirus 2 regulates the viral replication with targeting to the ORF23 (2/19/22) has been linked to the patented cure for all virus-driven diseases across kingdoms via Regulation of host and virus genes by neuronal miR-138 favours herpes simplex virus 1 latency (2/8/22) Who, besides our NIH Director, Lawrence A. Tabak and former President Trump is not surprised to see that researchers from Harvard collaborated with researchers from China to obfuscate the facts from the patent for…

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microRNA-mediated biodiversity (6)

February 14, 2022
James Kohl
Adaptations, Alternative Splicings, Autophagy, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Physics, replication timing, RNA Directed, RNA interference, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Variations, What's in the News
2 Comments

Tell me if you know a paleontologist or any other stupid theorist who is willing to discuss facts that link “Lessons from microRNA biology: Top key cellular drivers of Autosomal Dominant Polycystic Kidney Disease  to “… better understanding [of] the key processes resulting in pathophysiological changes that underlie disease.” Most theorists, especially paleontologists, seem willing to keep the diseases and their theories that link the virus-driven degradation of messenger RNA to the fossil record via extinctions and the Flood in…

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microRNA-mediated biodiversity (5)

February 13, 2022
James Kohl
Adaptations, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, What's in the News
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Criticisms of the nutrient-dependent pheromone-controlled evolutionary model 6/4/14 Editor’s note The 2013 review article by James Vaughn Kohl published in Socioaffective Neuroscience & Psychology and criticized in the above Letter to the Editor was subjected to standard peer review and the revised version was accepted by me after it had been accepted by both reviewers. Neo-Darwinian theorists still seem to think there is room for debate about the fact that nutrient stress and social stress have been linked to all…

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microRNA-mediated biodiversity (4)

February 13, 2022
James Kohl
Adaptations, biophotonics, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Physics, RNA Directed, RNA interference, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News
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The graphic representation of my Tweet impressions exemplifies the fact that Twitter regulates the dissemination of all accurate information, which links light-activated carbon fixation in cyanobacteria to microRNA-mediated protein folding chemistry and healthy longevity across kingdoms via God’s Creation of sunlight and humidity. See: Focus on Structure to Verify Protein Function  The structure of functional proteins is energy-dependent. By the end of the week that preceded Darwin Day 2022 celebrations, it appeared that most people, and all theorists, will continue…

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microRNA-mediated biodiversity (3)

February 6, 2022
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Physics, replication timing, RNA Directed, RNA editing, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity
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See first: The tipping point (revisited): 135K Conclusion: Eating food, for example, is the required link to ecological adaptations. See also: Museum für Naturkunde Explores Maria Sibylla Merian’s Legacy and Editions of Her Metamorphosis The Wondrous Transformation of Caterpillars and their Remarkable Diet of Flowers Moving forward: Fixation of amino acid substitutions in organized primate genomes is food energy-dependent. Pheromone-regulated genetic processes of reproduction link the fixation of the amino acid substitutions to sympatric speciation across kingdoms. This is how…

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The tipping point (revisited): 135K

February 5, 2022
James Kohl
Adaptations, Autophagy, base editing, biophotonics, Ecology, Light Energy, microRNA editing, Model Organisms, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity
One Comment

The tipping point (revisited): 110K (2) 10/22/20 Excerpt …seem to believe that President Trump’s claims about UV light and humidity have not been linked from the end of the COVID-19 nonsense to the end of their party, the end of Communism, the end of atheism, the end of racism and the end of all the liberal BS. Is the link from God’s Creation of UV light and water to ATP-dependent oxidative phosphorylation not perfectly clear to all intelligent people? I…

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microRNA-mediated biodiversity (2)

February 3, 2022
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News
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From microRNA-mediated biodiversity (1) See for comparison my blog posts that mention: glycine, which start with Epigenetic regulation of aging by glycine and GnRH 5/26/15 The focus here is on vertebrates, but the conserved molecular mechanisms extend across all species. Who else is watching science journalist John Hewitt continue on his collision course with reality? In Myelin is a gift from retroviruses 2/1/22, he again fails to link light-activated carbon fixation in cyanobacteria to biophysically constrained naturally attenuated viral endemicity…

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microRNA-mediated biodiversity (1)

February 1, 2022
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Subatomic, Variations
One Comment

I started this series to show biologically uninformed evolutionary theorist that all intelligent serious scientists know how stupid the theorists have always been A clinical and in-silico study of MicroRNA-21 and growth differentiation factor-15 expression in pre-diabetes, type 2 diabetes and diabetic nephropathy 2/1/22 RESULTS: MicroRNA-21 was found to directly target GDF15 downregulating transcription factors KLF4, TP53, and CEBPB. A significant difference in the levels of serum GDF15 was observed in Pre-diabetes (708.56 ±76.37), T2DM (1528.87 ±140.75) and DN patients…

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