RNA-mediated epigenetic regulation of gene expression

microRNA-mediated replication timing (1)

The phylogenetic utility and functional constraint of microRNA flanking sequences links the patent for naturally occurring light-activated carbon fixation to viral latency and healthy longevity across kingdoms. The patent: RNA-Guided Human Genome Engineering was linked from functional constraints to gain-of-function research in High-Quality Overlapping Paired-End Reads for the Detection of A-to-I Editing on Small RNA WHO failed to examine the problems associated with gain-of-function research, which researchers now suggest led to the creation of SARs-CoV-2. The creation of SARs-CoV-2 can be…

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Light-activated carbon fixation did not evolve (5)

See first: The tipping point (revisited): 120K 5/12/21 Church Speaks: The cyanobacteria fix [carbon via] light…Under ideal circumstances, they can be maybe seven to ten times more productive per photon.” George M. Church et al patented this naturally occurring process. On 5/12/21, I was pleasantly surprised to see the facts represented in this trail-side placard at Canyonlands National Park. The facts make this patent worthless: RNA-Guided Human Genome Engineering See why: Light-activated binding together of sand and other soil particles…

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Quantum biology vs atheism (2)

One year ago, on 4/23/20 former President Donald J. Trump linked sunlight and humidity to weakened Covid-19 via everything known to intelligent serious scientists about light-activated microRNA biogenesis, RNA interference, and biophysically constrained viral latency across kingdoms. On 4/24/20 Jonathan Reiner, professor of medicine at The George Washington University Hospital, said there’s no medical basis for Trump’s statements about sunlight. God’s Creation of sunlight and humidity were linked across kingdoms from Cascade diversification directs generation of neuronal diversity in the…

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Quantum biology vs atheism (1)

Peptide synthesis at the origin of life links quantum coherence to coherently organized biology via biophysically constrained viral latency. See: Identification of a micropeptide and multiple secondary cell genes that modulate Drosophila male reproductive success 4/13/21 A noncoding RNA generates amino acid peptides and energy-dependent sperm-competition phenotypes. Moving forward across species, see: Circular RNAs: Novel potential regulators in embryogenesis, female infertility, and pregnancy‐related diseases 4/20/21 Circular RNAs (circRNAs) are endogenous noncoding RNAs with unique cyclic structures. Although they were previously considered…

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Quantum Darwinism (8)

An engineered membrane-bound guanylyl cyclase with light-switchable activity 3/29/21 Expressing switch-Cyclop1 in the cells or tissue of interest will allow non-invasive and reversible manipulation of cGMP levels to a degree which is not possible by pharmacological intervention. The patented cure for all virus-driven pathology links naturally occurring light-activated carbon fixation to biophysically constrained viral latency. That means every intelligent person on Earth can help to end neo-Darwinian pseudoscientific nonsense by learning about quantum Darwinism. See for instance: RNA-Guided Human Genome…

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Quantum Darwinism (5)

See with my added emphasis: Parallel genetics of regulatory sequences using scalable genome editing in vivo 4/13/21 [Energy-dependent biophysically-constrained microRNA-mediated] Regulatory elements must ultimately be understood within their genomic environment and development- or tissue-specific contexts. Gene-centric theorists are too stupid to start with God’s Creation of energy, which must be linked from regulatory elements to regulation of the genomic environment before the effects of energy can be understood in any context whatsoever. See for context: Energy as information and constrained…

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Quantum Darwinism (2)

Nonenzymatic polymerase-like template-directed synthesis of acyclic l-threoninol nucleic acid 2/5/21 Orgel and Szostak introduced an amino group into 2′- and 3′-positions9, which enabled effective RNA copying due to acceleration of the ligation reaction10,11. Reported as: Origins of life could have started with DNA-like XNAs 4/6/21 …shorter L-aTNA fragments came together and linked up with each other on the longer L-aTNA template. Critically, this happened in the presence of a compound, called N-cyanoimidazole, and a metal ion, like manganese, both of…

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Pheromones protect us from viruses (9)

It may be a form of insanity that prevents theorists, atheists, and Communists from addressing the facts that have been detailed in the context of: Direct Observation of Protonation State Modulation in SARS-CoV-2 Main Protease upon Inhibitor Binding with Neutron Crystallography 3/23/21 …a class of agents called covalent peptidomimetic inhibitors that work by using strings of unnatural amino acids to bind to specific target proteins. See for instance:  A two-amino acid change in the hemagglutinin of the 1918 influenza virus…

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Pheromones protect us from viruses (7)

It’s been more than one year since Guenther Witzany published What is Life? 3/18/20 “A new definition of life must integrate the current empirical knowledge about interactions between cells, viruses, and RNA networks to provide a better explanatory power than the twentieth century narrative.” The need for the new definition of life is consistent with my claims from “What is life when it is not protected from virus-driven entropy.” It’s been 5 years since this virtual conference presentation on 3/30/16. The…

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Pheromones protect us from viruses (5)

Timothy Normand Miller (Digital circuit designer, software engineer, master debugger, computer engineering PhD, former college professor) @theosib2 wrote: If they didn’t mention God, then they didn’t make a link to God’s creation of anything. Adam Karaba (Assistant Professor, Department of Organic Technology, UCT Prague) @KarabaAdam wrote: I really dont like when anybody forces his faith into science, or issue his faith as a science. There is no place for such things in the science. It is not rational even ethic.…

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