RNA-mediated epigenetic regulation of gene expression

Quantum Darwinism (2)

Nonenzymatic polymerase-like template-directed synthesis of acyclic l-threoninol nucleic acid 2/5/21 Orgel and Szostak introduced an amino group into 2′- and 3′-positions9, which enabled effective RNA copying due to acceleration of the ligation reaction10,11. Reported as: Origins of life could have started with DNA-like XNAs 4/6/21 …shorter L-aTNA fragments came together and linked up with each other on the longer L-aTNA template. Critically, this happened in the presence of a compound, called N-cyanoimidazole, and a metal ion, like manganese, both of…

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Pheromones protect us from viruses (9)

It may be a form of insanity that prevents theorists, atheists, and Communists from addressing the facts that have been detailed in the context of: Direct Observation of Protonation State Modulation in SARS-CoV-2 Main Protease upon Inhibitor Binding with Neutron Crystallography 3/23/21 …a class of agents called covalent peptidomimetic inhibitors that work by using strings of unnatural amino acids to bind to specific target proteins. See for instance:  A two-amino acid change in the hemagglutinin of the 1918 influenza virus…

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Pheromones protect us from viruses (7)

It’s been more than one year since Guenther Witzany published What is Life? 3/18/20 “A new definition of life must integrate the current empirical knowledge about interactions between cells, viruses, and RNA networks to provide a better explanatory power than the twentieth century narrative.” The need for the new definition of life is consistent with my claims from “What is life when it is not protected from virus-driven entropy.” It’s been 5 years since this virtual conference presentation on 3/30/16. The…

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Pheromones protect us from viruses (5)

Timothy Normand Miller (Digital circuit designer, software engineer, master debugger, computer engineering PhD, former college professor) @theosib2 wrote: If they didn’t mention God, then they didn’t make a link to God’s creation of anything. Adam Karaba (Assistant Professor, Department of Organic Technology, UCT Prague) @KarabaAdam wrote: I really dont like when anybody forces his faith into science, or issue his faith as a science. There is no place for such things in the science. It is not rational even ethic.…

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Pheromones protect us from viruses (4)

Have you tried and repeatedly failed to put the pieces of a puzzle together? Did you claim it was impossible for anyone else to do it? To me, that exemplifies atheism. This helps to define atheism. Defining the underlying defect in insulin action in type 2 diabetes 3/17/21 …a broad signalling cascade mediated by changes in phosphorylation, gene expression and vesicular trafficking that result in increased nutrient utilisation and storage, and suppression of catabolic processes. The attempt to define the…

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Pheromones protect us from viruses (3)

Creationists link God’s sunlight-activated generation of energy from ambient humidity and the anaerobic production of magnetite in marine microbes to electron transfer. That is how they link the ATP-dependent Creation of RNA to ammonia detection via fixation of amino acid substitutions in protein nanowires. See: Harnessing Electricity-Producing Bacteria 3/2/21 Simply put: When humans eat, their bodies convert sugars from food into electrons. These electrons transfer to oxygen to produce energy that powers the metabolic processes of the cell. It is…

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Defeating disease and Communism (4)

On 3/16/21, Timothy Normand Miller, in his role as the stupid atheist, @theosib2 wrote: If there were any of the typical indications of a designer in DNA, then I would consider that there must have been a designer. However, none of those can be found. Peptide synthesis at the origin of life 11/13/20 and The Amino Acid Composition of Quadruplex Binding Proteins Reveals a Shared Motif and Predicts New Potential Quadruplex Interactors 9/13/18 were linked to Properties and biological impact…

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Defeating disease and Communism (3)

More than 117,000 published works that mention ‘microRNA‘ can be linked from: Playing games with quantum interference 3/10/21 via MicroRNAs organize intrinsic variation into stem cell states 3/5/20 and MicroRNA Involvement in Signaling Pathways During Viral Infection 3/10/20 to the game for ages 14+ Genotype. Everything known to intelligent serious scientists has been linked to Thomas Hunt Morgan’s claims about chromosomal rearrangements and sympatric speciation in flies and other insects. See also: Hypoxia associated multi-omics molecular landscape of tumor tissue…

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Defeating Disease and Communism (2)

On 4/23/20 former President Donald J. Trump reportedly linked God’s Creation of sunlight and humidity to the energy-dependent weakening of coronaviruses via RNA–RNA interaction between host and virus, but see Experts say there’s no medical basis for Trump’s suggestion that sunlight, disinfectants may treat coronavirus 4/24/20 Jonathan Reiner, professor of medicine at The George Washington University Hospital, said there’s no medical basis for Trump’s statements about sunlight. Reiner’s stupid claim can be placed into the context of “…a computational model…

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Pheromones protect us from viruses (1)

Involvement of transposable elements in neurogenesis 3/24/20 appeared in my search for indexed articles that mention microRNA on 3/4/21. There are more than 116,500 others. See: microRNA  MicroRNAs, many of which arise from transposon transcripts, also play an important role in regulating the differentiation of neuronal stem cells. That fact was established in the mid-1990s and was linked From Fertilization to Adult Sexual Behavior (1996) via pre-mRNA-mediated stem cell differentiation across kingdoms in our section on molecular epigenetics. At that time…

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