RNA-mediated epigenetic regulation of gene expression

Epigenetic inheritance of spatiotemporal regulation

May 22, 2018
James Kohl
Adaptations, biophotonics, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Physics, RNA Directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
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Excerpt: The perception of time thus varies between people and may depend at least in part on personality. These results open up a new avenue for studying and manipulating how we process social situations. This could eventually benefit people who struggle with social interactions, such as those with autism spectrum disorders. Link opens the pdf: Olfaction Warps Visual Time Perception Concluding paragraph: In physics, space-time is warped by the distribution of mass and energy in it (Hwaking 1988). Our findings,…

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Cracks in The Granite Wall (1)

May 17, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, What's in the News
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Researchers in Thailand linked US military service in Thailand during the time of the war in Vietnam from the time of the Korean War to denuclearization of North Korea via energy-dependent changes in the influenza B virus.   From scientific creationists in South Korea: A Single Amino Acid at the Polymerase Acidic Protein Determines the Pathogenicity of Influenza B Viruses   They obviously know how to create a virus that would decimate human populations in North Korea and in other…

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The eternal significance of microRNAs (8)

May 15, 2018
James Kohl
Adaptations, Diseases & Disorders, Ecology, microRNA editing, RNA Directed, RNA interference, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity
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Use of definitions in attempts to explain any aspect of species-specific biophysically constrained cell type differentiation and aging has been replaced by the use of model systems of biological processes.  Biological processes can be compared to so-called “evolutionary processes” to show that only biological processes need to be considered in the context of Darwin’s “conditions of life” or answers to the the question  What is Life? Schrödinger (1944). K. L. Mettinger et al. (eds.), Exosomes, Stem Cells and MicroRNA, Advances…

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Kohl’s Laws of Biology (codon-optimality revisited)

May 11, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News
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Summary: Kohl’s Laws help to explain what was missing from Darwin’s ‘conditions of life.’ Darwin knew nothing about genetics, which means he knew nothing about the epigenetic effects of food odors or pheromones. Ancient hepatitis B viruses from the Bronze Age to the Medieval period 5/7/18 We provide evidence for the creation of HBV genotype A via recombination, and for a long-term association of modern HBV genotypes with humans, including the discovery of a human genotype that is now extinct.…

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The eternal significance of microRNAs (7)

May 11, 2018
James Kohl
Adaptations, Alternative Splicings, Cytosis, Diseases & Disorders, Ecology, Model Organisms, RNA Directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, Subatomic
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Sales of human pheromone-enhanced fragrance products have been virtually eliminated by the pseudoscientific nonsense touted by neo-Darwinian theorists and Big Bang cosmologists. I may revisit their ridiculous claims at ScentofEros.com and Pheromones.com, but prefer to continue moving forward via my other domains: RNA-mediated.com and Autophagy.pro. Summary: 2018 Update: Sympatric speciation has been linked to species diversity as an example of an ecologically validated proof-of-concept in all living genera. Theorists, other psedoscientists and nearly all so-called science journalists have failed to…

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An evolutionary theory killer

ATP and RNA-mediated chromosomal stability

May 9, 2018
James Kohl
Adaptations, Alternative Splicings, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic
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Cytosis, a cell biology game for ages 10+ links ATP to viral latency and the protection of all organized genomes from the virus-driven degradation of messenger RNA that serious scientists have linked to all pathology. It is time for a new measure of cell function: Quantifying Cellular ATP Production Rate…(2018) Adenosine triphosphate (ATP) is the most common high energy intermediate of living organisms. Cells utilize the energy derived from the breakdown of cellular fuels to synthesize ATP from ADP and…

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An evolutionary theory killer

A single base change refutes theistic evolution (2)

May 9, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic
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Announcing publication of a model that links the creation of quantized energy from changes in subatomic particles to biophysically constrained viral latency and sympatric speciation in all living genera. Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems This angstroms to ecosystems model of ecological adaptation links nutrient energy-dependent epigenetic effects on base pairs and amino acid substitutions to pheromone-controlled changes in the microRNA/messenger RNA balance and chromosomal rearrangements via the physiology of reproduction in species from microbes to humans. The…

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Nutrient-dependent pheromone-controlled feedback loops

May 3, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations, What's in the News
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Summary: The link from positive selection to one food energy-dependent base pair change and fixation of the mouse-model-to-human-specific EDAR V370A allele in populations on different continents attests to sympatric speciation at every level of examination that refutes the pseudoscientific nonsense of neo-Darwinian mutation-driven evolution. Reported on 5/3/18 as: SWAT team of immune cells found in mother’s milk  1) “There is a feedback loop,” says Yu. It’s known that some immune cells like leucocytes, another white blood cell that fights infection,…

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EDAR V370A and sympatric speciation

May 3, 2018
James Kohl
Adaptations, Diseases & Disorders, Ecology, Model Organisms, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity, Variations
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Nick Lane and others like him refuse to reappraise their human mitochondrial DNA recombination dogma. All serious scientists know where the energy for recombination comes from. But, in his latest video clip, he touts the same unsubstantiated theoretical pseudoscientific nonsense. See the: Aeon Video: Life on earth – from mushrooms to humans and everything in between – seems enormously diverse. At the cellular level, however, almost all complex lifeforms are surprisingly similar. Why life is this way, though, remains mysterious.…

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Ecological Adaptations vs the Randomness of Evolution (2)

May 1, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, microRNA editing, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations
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Summary: See for comparison: Make ‘Em Resistant to Viruses In the new proposal — which Science says was released in advance of a meeting today — GP-write leaders say “ultrasafe” cells could be developed by making some 400,000 changes to the human genome. A Fast One–Step Digestion of DNA or RNA for Global Detection and Characterization of Nucleotide Modifications (link opens pdf) Product information: The Nucleoside Digestion Mix is an optimized mixture of enzymes that provides a convenient one-step method…

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