RNA-mediated toxicity

God’s microRNA-mediated Creation of genotypes (2)

More than 127,000 indexed published works link God’s energy-dependent Creation of microRNAs to all biodiversity via energy-dependent microRNA-mediated DNA supercoiling . See: microRNA See first: God’s microRNA-mediated Creation of genotypes (1) See also: MiR-125b regulates the differentiation of hair follicles in Fine-wool Sheep and Cashmere goats by targeting MXD4 and FGFR2 9/6/21 If you can’t link this to chromosomal rearrangements and sympatric speciation in species from flies to labradoodles, you haven’t played the STEM toy for ages 14+ “Genotype.” One…

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Natural selection for adaptation (8)

Facts about natural selection for adaptation can be compared to theories of Evolution by Gene Duplication (1970) The creation of metazoans, vertebrates and finally mammals from unicellular organisms… required the creation of new gene loci with previously nonexistent functions. The persistent theories of evolution by gene duplication can be compared to facts natural selection for adaptation in the context of God’s Creation of subatomic particles, such as protons and the ATP-dependent creation of RNA, which was required to link the…

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Natural selection for adaptation (7)

Microbial signatures in the lower airways of mechanically ventilated COVID-19 patients associated with poor clinical outcome 8/31/21 was reported as: High virus count in the lungs drives COVID-19 deaths 8/31/21 …the study revealed that those who died had on average 50 percent lower production of a type of immune chemical that targets the coronavirus compared with the COVID-19 patients who survived the illness. These customized proteins are part of the body’s adaptive immune system, a subset of cells and chemicals…

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Natural selection for adaptation (5)

See first: Natural selection for adaptation (4) If you have not yet linked God’s Creation of energy-as-information from the pH-dependent physiology of reproduction to biophysically constrained viral latency and all phenotypes, start with Regulation of MicroRNAs 8/26/21. For comparison, Charles Darwin invented his theory based on no ability to observe biophysically constrained energy-dependent top-down causation at the molecular level. He bred pigeons, which led him to focus on morphology and link the food that finches ate to beak morphology because…

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Natural selection for adaptation (4)

See first: Natural selection for adaptation (3) See also: “pericentromeric satellite RNA expression” Did you mean “pericentromeric satellite dna expression” No. I am not a stupid gene-centric theorist. I am a Creationist who knows how energy-dependent supercoiled DNA is Created. For instance, light-activated microRNA-mediated “Biogenesis is regulated by many checkpoints at every step, primarily at the transcriptional level, in the nucleus, cytoplasm, with RNA regulation, RISC loading, miRNA strand selection, RNA methylation/uridylation, and turnover rate.” If you have not yet…

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MicroRNA-mediated population control (10)

32694 impressions in 1 day. 8/12/21 Virus-driven degradation of mRNA has been linked to all pathology & microRNA-mediated DNA repair links oxidative phosphorylation to the stability of all organized genomes via natural selection for energy-dependent codon optimality and God’s microRNA-mediated stem cell Creation. Researchers who understand energy-dependent cell type Creation are moving forward with facts that refute all the stupid theories touted by neo-Darwinists and Big Bang cosmologists. See: Deciphering epigenetic(s) role in modulating susceptibility to and severity of COVID-19…

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MicroRNA-mediated population control (7)

Quantum coherence was linked across kingdoms to coherently organized biology in MicroRNAs organize intrinsic variation into stem cell states and via the STEM toy for ages 14+ Genotype. Every fact that links quantum coherence to coherently organized biology via the energy-dependent structural diversity of supercoiled DNA and microRNA-mediated stem cell Creation via RNA interference (#RNAi) was replaced by claims of cryptic transcription in mammals. See: Altered chromatin states drive cryptic transcription in aging mammalian stem cells 8/2/21 We show that…

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MicroRNA-mediated population control (5)

Visualizing a protonated RNA state that modulates microRNA-21 maturation 10/26/20 and Visualization and characterization of RNA–protein interactions in living cells 7/27/21 cannot be linked to stupid theories about the automagical emergence of energy from the cosmic void or theories that link beneficial mutations during the past billions to millions of years to our evolution from pond scum or light-activated carbon fixation in cyanobacteria. For contrast, the visualizations support this claim: “Post-transcriptional modifications, especially phosphorylation play crucial roles in regulation of…

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microRNA-mediated election cycles (7)

Are multi-quasiparticle interactions important in molecular ionization? 3/28/21 GWΓ [calculations] offers a unified description across all relevant energy scales. Our results suggest that the multi-QP regime corresponds to dynamical correlations, which can be described via perturbation theory. Few intelligent serious scientists understand the complexities of calculations needed to link God’s Creation of energy-as- information to biophysically constrained viral latency and healthy longevity across kingdoms. Most of them know what happens when a paradigm fails. Pseudoscientists know when they got stuck…

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microRNA-mediated replication cycles (9)

See first: microRNA-mediated replication cycles (8) Rotavirus research: 2014-2020 7/2/21 A temperature sensitive mutant… in the triplet encoding amino acid 138 of VP1 (L138P)…was separately expressed as a… protein, shown to interact with viroplasm-like particles (VLPs) in uninfected cells and to synthesize RNA in vitro…” My summary: The rotavirus steals the energy required for the ATP-dependent synthesis of RNA, which typically biophysically constrains viral latency across kingdoms. Contextual constraints occur via light-activated carbon fixation, oxidative phosphorylation and RNA interference (RNAi).…

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