RNA-mediated toxicity

Codon optimality vs systemic fraud (4)

A good model predicts. See: From Fertilization to Adult Sexual Behavior (1996). In our section on molecular epigenetics we predicted that A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins 6/16/22 would be linked to food energy and pheromone-regulated genetic processes of reproduction across kingdoms. On 6/23/22, that fact was placed back into the context of stupid theories. See: Abracadabra, One Becomes Two: The Importance of Context in Viral −1 Programmed Ribosomal Frameshifting  Yeast and potentially mammalian cells,…

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Codon optimality vs systemic fraud (2)

See first: Codon optimality vs systemic fraud (1) Researchers identified over 5,500 new viruses in the ocean, including a missing link in viral evolution 4/8/22 and Ocean water samples yield treasure trove of RNA virus data 4/8/22 attest to facts about the Footprints of a Singular 22-Nucleotide RNA Ring at the Origin of Life 4/25/20 that link God’s ATP-dependent Creation of RNA from RNA-peptide interactions at the origin of life to the Mapping and characterization of structural variation in 17,795…

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Codon optimality vs systemic fraud (1)

Two summaries of neo-Darwinian evolutionary theory: Amino acid composition of proteins varies substantially between taxa and, thus, can evolve. …yeast receptors trigger activation of heterotrimeric G proteins just as mammalian receptors do, this conserved signaling pathway must have been present in the common ancestor of yeast and humans. Unless you are a biologically uninformed theorist, see first Epistemic corruption (10) Watch for my next 10-part series on Codon optimality vs systemic fraud. I will link it to the fraudulent representations…

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Epistemic corruption (10)

Biosynthesis of cyanobacterin, a paradigm for furanolide core structure assembly 5/26/22 Full functional evaluation of the recombinant key enzymes in vivo and in vitro, individually and in concert, provided in-depth mechanistic insights into a streamlined C–C bond-forming cascade that involves installation of compatible reactivity at seemingly unreactive Cα positions of amino acid precursors. Our work extends the biosynthetic and biocatalytic toolbox for γ-butyrolactone formation, provides a general paradigm for furanolide biosynthesis and sets the stage for their targeted discovery, biosynthetic…

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Epistemic corruption (6)

Summary: The rapid pace of experimental evidence linked to Selective MicroRNA-Offset RNA Expression in Human Embryonic Stem Cells 3/30/15 can be compared to the nonsense touted by neo-Darwinian theorists published as Shining Light on the Evolution of Photosynthesis 12/1/03 Photosynthetic bacteria and eukaryotes collect light energy for photosynthesis in structures called light-harvesting antenna complexes. Unless the light-harvesting complexes automagically created themselves, the facts about God’s Creation of sunlight link light-activated carbon fixation in cyanobacteria to pH-dependent microRNA-mediated protein folding chemistry,…

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MicroRNA-mediated existential threats (4)

See first:  MicroRNA-mediated existential threats (3) On 4/19/22 I posed this question on Twitter. Why do people believe stupid theories about the evolution of amino acid composition in proteins, which requires them to ignore everything known to intelligent serious scientists about how SARS-CoV-2 synthetic mRNA vaccinations altered biophysically constrained viral endemicity? 4/19/22 How can it not be perfectly clear that stupid theories about the evolution of amino acid composition in proteins ignore everything known to all intelligent serious scientists about…

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MicroRNA-mediated existential threats (3)

“Footprints of Multiple Interspecies Re-assortment Events” (4/16/18) link the failed efficacy of COVID19 vaccines,  to the microRNA-mediated future of humanity via patents held for therapeutic solutions by Thomas E. Eichim et al., in the context of former President Trump’s claim on 4/23/20 about light-activated protein folding chemistry and Characteristics of the MicroRNA Expression Profile of Exosomes Released by Vero Cells Infected with Porcine Epidemic Diarrhea Virus  (indexed on 4/23/22) Details: Exosomes… contain regulated microRNA (miRNA), allowing them to function in…

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MicroRNA-mediated existential threats (2)

On 6/26/19, a friend and I stopped at the Scopes Museum in Dayton, Tennessee to make sure I could view this presentation on my laptop computer via a hotspot wi-fi connection. See: Genome-Wide Study Reveals a Novel Regulatory Pathway: Translation Affects mRNA Stability in a Codon-Dependent Manner 6/26/19 (available for free on demand with registration). I may try to find my pictures, or my on-location video to show that, as predicted, the presentation put an end to all the nonsense…

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MicroRNA-mediated existential threats (1)

See: RNA-mediated silencing (10) Second request for clarification. Do any of your #patents link naturally occurring light-activated #carbon_fixation in #cyanobacteria to biophysically constrained #microRNA-mediated protein folding #chemistry & #viral_endemicity across kingdoms via https://www.kickstarter.com/projects/geniusgames/cellulose-a-plant-cell-biology-game Cellulose Happy Easter! Thomas E. Ichim and others hold patents on food energy-dependent pheromone-regulated genetic processes of microRNA-mediated protein folding chemistry and the pH-dependent physiology of reproduction. Non-disclosure would be an existential threat to the microRNA-mediated future of humanity. See parts 1-10 of the series: The microRNA-mediated…

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RNA-mediated silencing (10)

Stopping pandemics before they start: Lessons learned from SARS-CoV-2 3/11/22 The impact of COVID-19 on human health in 2020 alone was estimated to be estimated  to cost more than $2 trillion. Light-activated pH-dependent carbon fixation in cyanobacteria and microRNA-mediated protein folding chemistry clearly link the potential of hydrogen (pH) to all biodiversity on Earth via MicroRNAs in Mechanical Homeostasis 4/4/22. Food energy-dependent pheromone-regulated genetic processes of RNA interference (RNAi) and biophysically constrained viral endemicity across kingdoms were linked from the…

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