RNA methylation

Natural selection for adaptation (4)

See first: Natural selection for adaptation (3) See also: “pericentromeric satellite RNA expression” Did you mean “pericentromeric satellite dna expression” No. I am not a stupid gene-centric theorist. I am a Creationist who knows how energy-dependent supercoiled DNA is Created. For instance, light-activated microRNA-mediated “Biogenesis is regulated by many checkpoints at every step, primarily at the transcriptional level, in the nucleus, cytoplasm, with RNA regulation, RISC loading, miRNA strand selection, RNA methylation/uridylation, and turnover rate.” If you have not yet…

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MicroRNA-mediated population control (7)

Quantum coherence was linked across kingdoms to coherently organized biology in MicroRNAs organize intrinsic variation into stem cell states and via the STEM toy for ages 14+ Genotype. Every fact that links quantum coherence to coherently organized biology via the energy-dependent structural diversity of supercoiled DNA and microRNA-mediated stem cell Creation via RNA interference (#RNAi) was replaced by claims of cryptic transcription in mammals. See: Altered chromatin states drive cryptic transcription in aging mammalian stem cells 8/2/21 We show that…

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MicroRNA-mediated population control (5)

Visualizing a protonated RNA state that modulates microRNA-21 maturation 10/26/20 and Visualization and characterization of RNA–protein interactions in living cells 7/27/21 cannot be linked to stupid theories about the automagical emergence of energy from the cosmic void or theories that link beneficial mutations during the past billions to millions of years to our evolution from pond scum or light-activated carbon fixation in cyanobacteria. For contrast, the visualizations support this claim: “Post-transcriptional modifications, especially phosphorylation play crucial roles in regulation of…

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microRNA-mediated replication cycles (9)

See first: microRNA-mediated replication cycles (8) Rotavirus research: 2014-2020 7/2/21 A temperature sensitive mutant… in the triplet encoding amino acid 138 of VP1 (L138P)…was separately expressed as a… protein, shown to interact with viroplasm-like particles (VLPs) in uninfected cells and to synthesize RNA in vitro…” My summary: The rotavirus steals the energy required for the ATP-dependent synthesis of RNA, which typically biophysically constrains viral latency across kingdoms. Contextual constraints occur via light-activated carbon fixation, oxidative phosphorylation and RNA interference (RNAi).…

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microRNA-mediated replication cycles (8)

In 365 days, after celebration of independence from public health fascism on Independence Day 2022 in the USA, Guenther Witzany, co-author of Infectious Thoughts: Discovering Biology as a Social Science will end the pseudoscientific nonsense about beneficial mutations and evolution across billions to millions of years via his efforts to organize and to present during this conference. How Evolution Learnt to Learn 7/6/22 – 7/9/22 Representations of the solar analemma, the Mobius strip, examples of infinity, and microRNA-mediated replication cycles…

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microRNA-mediated replication cycles (6)

Conclusion from microRNA-mediated replication timing (5) 7/2/21 …the color and fragrance of flowers depends on light-activated microRNA-mediated replication timing in the context of RNA interference. See: Striking a balance: Trade-offs shape flower diversity 7/1/21 Celebrate your freedom from atheism, Communism, and public health fascism on Independence Day 2021. Light-activated carbon fixation has linked CRISPR-Cas Systems: RNA-mediated Adaptive Immunity in Bacteria and Archaea (2013) to the prevention or effective treatment of all virus-driven diseases via this patent: RNA-Guided Human Genome Engineering…

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microRNA-mediated replication timing (5)

Facts about energy-dependent microRNA-mediated biophysical constraints, which link protonated RNA interference (RNAi) to cell type differentiation across kingdoms via the physiology of reproduction and fixation of amino acid substitutions in organized genomes, are included in: pre-mRNA spatial distributions suggest that splicing can occur post-transcriptionally 6/29/21 Our results suggest a model in which transcription and splicing are largely independent, and the existence of a slow moving zone around the transcription site allows for the unification of co-transcriptional and post-transcriptional models of…

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microRNA-mediated replication timing (4)

See first: microRNA-mediated replication timing (1) 6/17/21 microRNA-mediated replication timing (2) 6/27/21 microRNA-mediated replication timing (3) 6/29/21 Non-B DNA: a major contributor to small- and large-scale variation in nucleotide substitution frequencies across the genome 1/15/21 was reported on 6/29/21 as Study provides first genome-wide evidence for functional importance of unusual DNA structures Some regions of the human genome where the DNA can fold into unusual three-dimensional structures called c (G4s) show signs that they are preserved by natural selection. The…

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microRNA-mediated replication timing (3)

miRNAs; a novel strategy for the treatment of COVID-19 6/28/21 Several previous studies have shown that host miRNAs play an anti-viral role and improve the treatment of patients with COVID-19. miRNAs by binding to the 3′-UTR or 5′-UTR of viral RNA play an important role in COVID-19-host interplay and viral replication. That fact makes it easier to convict Facebook of crimes against humanity because their censors prevent me from including links to autophagy.pro, and to microRNA.pro which expose the scientific…

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microRNA-mediated replication timing (2)

Transcription typically requires the energy-dependent Creation of the enzyme RNA polymerase. Intelligent serious scientists know that enzymes do not automagically create themselves, and most of them realize that transcription began when God Created the anti-entropic virucidal energy of sunlight. The 6/4/21 cover of Science Magazine, places that fact about biophysically constrained transcription into the context of pH-dependent oxidative phosphorylation. However, McEwen et al’s claims from 1964 are not included in the content from “Structures of the human Mediator and Mediator-bound…

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