Variations

God’s microRNA-mediated Creation of genotypes (5)

Summary: Energy-dependent changes in single nucleotide polymorphisms (SNPs) in microribonucleic acids (microRNAs/miRNAs) were linked from femotosecond blasts of UV light to DNA repair via an extremely sensitive assay for the label-free optical detection and suppression of interfering effects caused by non-specific binding. Interactions in Augmented and Mixed Reality: An Overview 9/20/21 (This article belongs to the Special Issue Extended Reality: From Theory to Applications) All interactions are energy-dependent and microRNA-mediated. ~250 newly indexed articles attest to that fact, which is…

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God’s microRNA-mediated Creation of genotypes (4)

Non-random distribution of individual genetic diversity along an environmental gradient 6/12/09 links the energy-dependent Creation of ecologically relevant phenotypes to pH-dependent biophysically constrained viral latency across kingdoms via single nucleotide polymorphisms (SNPs) in microRNAs (miRNAs). See also:  T cell immune responses to SARS-CoV-2 and variants of concern (Alpha and Delta) in infected and vaccinated individuals 9/16/21 …we report on T cell immunity in infected and vaccinated individuals, identifying CD4+/CD8+ T cell cytokine responses to SARS-CoV-2 and variant peptides… Light-activated carbon…

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Natural selection for adaptation (10)

See: Ignoring light-activated microRNA biogenesis 10/16/18, and compare our section on pre-mRNAs and molecular epigenetics in: From Fertilization to Adult Sexual Behavior (1996) to MicroRNAs buffer genetic variation at specific temperatures during embryonic development 10/16/18, which was previously published sans mention of microRNAs as Temporal development of Drosophila embryos is highly robust across a wide temperature range 7/11/18 Changing the term from pre-mRNAs to microRNAs obfuscated food energy-dependent pheromone-regulated genetic processes of cause and effect, but see ~127,000 indexed publications…

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Natural selection for adaptation (8)

Facts about natural selection for adaptation can be compared to theories of Evolution by Gene Duplication (1970) The creation of metazoans, vertebrates and finally mammals from unicellular organisms… required the creation of new gene loci with previously nonexistent functions. The persistent theories of evolution by gene duplication can be compared to facts natural selection for adaptation in the context of God’s Creation of subatomic particles, such as protons and the ATP-dependent creation of RNA, which was required to link the…

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Natural selection for adaptation (5)

See first: Natural selection for adaptation (4) If you have not yet linked God’s Creation of energy-as-information from the pH-dependent physiology of reproduction to biophysically constrained viral latency and all phenotypes, start with Regulation of MicroRNAs 8/26/21. For comparison, Charles Darwin invented his theory based on no ability to observe biophysically constrained energy-dependent top-down causation at the molecular level. He bred pigeons, which led him to focus on morphology and link the food that finches ate to beak morphology because…

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MicroRNA-mediated population control (8)

See: MicroRNA-mediated population control (7) Peptide synthesis at the origin of life 11/13/20 was linked to treatment with light inside the body via Visualizing a protonated RNA state that modulates microRNA-21 maturation 10/26/20, which appeared first as a preprint on 11/23/19 Everything known to intelligent serious scientists links God’s Creation of energy-as-information to biophysically constrained viral latency via the physiology of reproduction across kingdoms. See also: “Geographic Co-distribution of Influenza Virus Subtypes H7N9 and H5N1 in Humans, China,” (2013) which cites…

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MicroRNA-mediated population control (7)

Quantum coherence was linked across kingdoms to coherently organized biology in MicroRNAs organize intrinsic variation into stem cell states and via the STEM toy for ages 14+ Genotype. Every fact that links quantum coherence to coherently organized biology via the energy-dependent structural diversity of supercoiled DNA and microRNA-mediated stem cell Creation via RNA interference (#RNAi) was replaced by claims of cryptic transcription in mammals. See: Altered chromatin states drive cryptic transcription in aging mammalian stem cells 8/2/21 We show that…

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microRNA-mediated election cycles (6)

Hyperglycaemia Induces Trained Immunity in Macrophages and Their Precursors and Promotes Atherosclerosis 7/13/21 Conclusions: Hyperglycaemia-induced trained immunity… suggests new targets for disease prevention and therapy. Reported on 7/14/21 as High blood sugar levels ‘reprogram’ stem cells Our study is the first to show that diabetes causes long-term changes to the immune system… By focussing too narrowly on a managing a person’s blood sugar levels we’re only addressing part of the problem. Every intelligent serious scientist in the world already knows…

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microRNA-mediated election cycles (4)

Computational designing of a peptide that potentially blocks the entry of SARS-CoV, SARS-CoV-2 and MERS-CoV and A paradigm shift in cell-free approach: the emerging role of MSCs-derived exosomes in regenerative medicine 7/12/21 support the same conclusion: God’s Creation of sunlight and humidity link Peptide synthesis at the origin of life 11/13/20 from biophysically constrained viral latency to healthy longevity across kingdoms via the physiology of reproduction and Biblical Genesis. See: microRNA-mediated election cycles (3) If you can’t link the works…

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