Variations

From optoribogenetics to HelioRiboGenetics (7)

Charting a Coronavirus Infection 10/5/20 “After months of downplaying the threat of the Covid-19 pandemic, President Trump…” …was vindicated when Roger Penrose won a Nobel Prize in Physics on October 6, 2020.  In 1991, Penrose indirectly linked food energy from quantum coherence to coherently organized biology via God’s claims in Biblical Genesis. See: What is Life?: With Mind and Matter and Autobiographical Sketches (Canto Classics) Reprint Edition by Erwin Schrodinger/Penrose (Author) How often do we still hear that quantum effects…

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pH-dependent viral latency (6)

See first: pH-dependent viral latency (5) Researchers from Iran linked light-activated microRNA biogenesis in plants to the expression genes that effect the number, size and/or the pH of pathways that influence melanin synthesis in the context of human iris color and human skin pigmentation via the L‐tyrosine amino acid precursor. The claim on 6/5/20 by Frank M. LaFerla about the links from energy-dependent changes in microbes to humans and racism was retracted on the same day. Thank God, scientific Creationists…

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The microRNA-mediated future of humanity (8)

The levels of complexity linked to the microRNA-mediated future of humanity can be examined by ages 10-14+ via game-play of: Bacillus (failed project) See instead: Function of miR825 and miR825* as Negative Regulators in Bacillus cereus AR156-elicited Systemic Resistance to Botrytis cinerea in Arabidopsis thaliana 10/17/19 Peptide Players compete to link amino acids to build a peptide chain (a fancy word for a protein). Virulence Players take on the role of viruses and compete to infect a host cell in…

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The microRNA-mediated future of humanity (5)

Coronavirus facts from Scientific Creationists in South Korea (reported as a coronavirus tip to Business Insider on 5/1/2020) Re: “South Korea says recovered coronavirus patients who tested positive again did not relapse: Tests picked up ‘dead virus fragments’ Summary: Scientists from the so-called “Creationist Capital of the World” linked inaccurate test results to the end of the ongoing well-orchestrated coronavirus crisis. They also linked President Trump’s claims about UV light-activated microRNA biogenesis to protection from stress-linked virus-driven pathology in all…

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Natural models inspire future therapeutics (2)

Summary: Food odors and pheromones biophysically constrain viral latency, and an effective treatment for all neurodegenerative diseases was proposed in this 2011 patent application “Pheromones and the luteinizing hormone for inducing proliferation of neural stem cells and neurogenesis“ See for comparison: Identification of miR-379/miR-656 (C14MC) cluster downregulation and associated epigenetic and transcription regulatory mechanism in oligodendrogliomas. The post- transcriptionally regulatory network of this cluster showed enrichment of key cancer-related biological processes such as cell adhesion and migration. Also, there was…

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An evolutionary theory killer

Quantum initiation of cold chemistry vs Hypeology (1)

Cold chemistry with two atoms Summary For centuries, chemists have written equations representing chemical reactions by using symbols for atoms and molecules; for example, 2H2O + 2Na → 2NaOH + H2. This short notation shows only four reacting particles, but even in a classroom demonstration where a small piece of sodium is dropped in water, the total number of reactants will be on the order of Avogadro’s number (∼6 × 1023). On page 900 of this issue, Liu et al.…

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Virus-driven genome engineering causes cancer?

CRISPR–Cas9 genome editing induces a p53-mediated DNA damage response Inhibition of p53 prevents the damage response and increases the rate of homologous recombination… In the 1990’s, Abcam researchers discovered the cell death gene. Now see: Mechanisms of Recombination conference See also: P53 toxicity is a hurdle to CRISPR/CAS9 screening and engineering in human pluripotent stem cells We demonstrated the toxic response is tp53-dependent and the toxic effect of tp53 severely reduces the efficiency of precise genome-engineering in hPSCs. Reported as:…

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An evolutionary theory killer

The concept of a species (3)

Gene expression evidence for remodeling of lateral hypothalamic circuitry in cocaine addiction (2005) This remodeling of LH circuitry could contribute to the chronic deficit in reward function that has been hypothesized to drive the transition to drug addiction. Lena D. van der Stap discussed her role in the publication of this article, which failed to make any assumptions about mutations and/or evolution. James Kohl Did you co-author Gene expression evidence for remodeling of lateral hypothalamic circuitry in cocaine addiction McEwen told…

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The concept of a species (1)

In an attempt to discuss The misleading evidence that fooled scientists for decades I wrote: The concept of a species is clearly seen in the context of Darwin’s “conditions of life” and sympatric speciation. What organisms eat is linked from their physiology of pheromone-controlled reproduction to biophysically constrained viral latency and all extant biodiversity via energy-dependent changes in base pairs and fixation of amino acid substitutions in the organized genomes of species from microbes to humans. See Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From…

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The tipping point (revisited): 74,000 publications

President Trump and Kim Jong Un will probably discuss this fact: All serious scientists have learned that quantized energy-dependent microRNA biogenesis links everything known about the creation of sunlight from the physiology of food energy-dependent pheromone-controlled reproduction to viral latency and healthy longevity in the context of the creation of the innate immune system of bacteria. See also: The tipping point (revisited): 73,000 publications May 16, 2018 In less than one month, nearly 1000 publications have been added to the…

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