Critical Role of Histone Turnover in Neuronal Transcription and Plasticity Reported as: Lifelong learning is made possible by recycling of histones, study says Also reported as: New epigenetic mechanism revealed in brain cells Excerpt: In humans, researchers used a technique called 14C/12C bomb pulse dating to measure turnover. The technique is based on the fact … “New” epigenetic mechanism for lifelong learning?
Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems Abstract excerpt: … links nutrient-dependent epigenetic effects on base pairs and amino acid substitutions to pheromone-controlled changes in the microRNA / messenger RNA balance and chromosomal rearrangements. The nutrient-dependent pheromone-controlled changes are required for the thermodynamic regulation of intracellular signaling, which enables biophysically constrained nutrient-dependent protein folding… … microRNAs and memory: Why trust a theory?
Distinct lineages of Ebola virus in Guinea during the 2014 West African epidemic Excerpt: The data presented here indicates EBOV is able to generate and fix nucleotide and amino acid variation within co-circulating viral lineages on the time-scale of individual outbreaks, including the presence of country-specific lineages, and which may ultimately produce variants with important … Virus-driven death by evolutionary theory
New inorganic aromatic ion Excerpt: Aromatic molecules are a staple of organic chemistry. This comment was removed by the site staff for violation of the comments guidelines : Excerpt: “… when a molecule that looks perfectly reasonable does not exist, the reason may be as simple as nobody has yet found a way to make … What I cannot create I eliminate from discussion
The Arthur M. Sackler Colloquia are sources for up-to-date information about biologically based cause and effect, which links epigenetic effects on hormones to the affects of hormones on behavior. The difference between effect and affect was place into the context here: Correction for McEwen, Brain on stress: How the social environment gets under the skin … RNA-mediated development
Why Do Healthy People Have Harmful Mutations? By Ricki Lewis, PhD Posted: June 4, 2015 Excerpts: More intriguing were the 43 participants who had disease-causing genotypes, but were healthy. Further investigation found biochemical evidence, symptoms, or telling characteristics. Figuring out all the interactions that underlie gene expression is a challenge that dwarfs that of sequencing … Healthy mutants
Rejecting Evolutionary Psychology is Rejecting Evolution Discussion on the closed group Applied Evolutionary Psychology includes my comments on several other reports, beginning with: My comments on: Early Code New research points to key properties of transfer RNA molecules and amino acids that may have supported the origin of life on Earth. I wrote: Thanks for … Rejecting pseudoscientific nonsense
The Living Set Mathematical and computational approaches are making strides in understanding how life might have emerged and organized itself from the basic chemistry of early Earth. By Wim Hordijk | June 1, 2015 Excerpt: Put some E. coli in a dish with appropriate nutrients, and after a few days the dish will be teeming … Living the life that randomness created? (Sarcasm alert)
Summary: Given what is currently known about RNA-mediated cell type differentiation in all genera, it may be impossible for theorists to link mutations to evolution via glycosylation. miRNA proxy approach reveals hidden functions of glycosylation Abstract excerpt: Glycosylation, the most abundant posttranslational modification, holds an unprecedented capacity for altering biological function. Journal article excerpt: …glycans … microRNAs, glycosylation, and genomes
What are microRNAs? Excerpt: MicroRNAs have been shown to be involved in a wide range of biological processes such as cell cycle control, apoptosis and several developmental and physiological processes including stem cell differentiation, hematopoiesis, hypoxia, cardiac and skeletal muscle development, neurogenesis, insulin secretion, cholesterol metabolism, aging, immune responses and viral replication. In addition, highly … DNA organization, structure, and function
