What’s in the News

From optoribogenetics to HelioRiboGenetics (7)

October 7, 2020
James Kohl
Adaptations, base editing, biophotonics, Diseases & Disorders, Ecology, Light Energy, Physics, RNA interference, Variations, What's in the News
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Charting a Coronavirus Infection 10/5/20 “After months of downplaying the threat of the Covid-19 pandemic, President Trump…” …was vindicated when Roger Penrose won a Nobel Prize in Physics on October 6, 2020.  In 1991, Penrose indirectly linked food energy from quantum coherence to coherently organized biology via God’s claims in Biblical Genesis. See: What is Life?: With Mind and Matter and Autobiographical Sketches (Canto Classics) Reprint Edition by Erwin Schrodinger/Penrose (Author) How often do we still hear that quantum effects…

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From optoribogenetics to HelioRiboGenetics (6)

October 7, 2020
James Kohl
Adaptations, biophotonics, Diseases & Disorders, Ecology, Light Energy, Physics, RNA Directed, RNA interference, RNA–Mediated Epigenetic Heredity, Subatomic, What's in the News
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“How often do we still hear that quantum effects can have little relevance in the study of biology, or even that we eat food in order to gain energy?” 8/8/91 2020 Physics Nobel Laureate, Roger Penrose linked the answer to his rhetorical question from physics to chemistry and molecular biology via the refutation of neo-Darwinian pseudoscientific nonsense and Big Bang cosmology. Quantum coherence has since been linked to coherently organized biology. See: MicroRNAs organize intrinsic variation into stem cell states…

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UV light, H2O, and epigenetic effects… (3)

September 26, 2020
James Kohl
Adaptations, biophotonics, Diseases & Disorders, Ecology, Light Energy, Physics, RNA Directed, RNA editing, RNA interference, RNA–Mediated Epigenetic Heredity, Subatomic, What's in the News
One Comment

Trump nominates conservative Amy Coney Barrett for Supreme Court She would be the only justice on the current court not to have received her law degree from an Ivy League school. The eight current justices all attended either Harvard or Yale. Most researchers at Harvard and Yale failed to admit, and failed to teach their students, that God’s Creation of UV light and water biophysically constrains viral latency across kingdoms via oxidative phosphorylation. They are being forced to tell the…

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The microRNA-mediated fight against COVID-19 (1)

August 21, 2020
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, Nutrigenomics, Pharmacogenomics, Physics, RNA interference, What's in the News
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History (1) Nutrient-dependent/pheromone-controlled adaptive evolution: a model (2013) …the epigenetic ‘tweaking’ of the immense gene networks that occurs via exposure to nutrient chemicals and pheromones can now be modeled in the context of the microRNA/messenger RNA balance, receptor-mediated intracellular signaling, and the stochastic gene expression required for nutrient-dependent pheromone-controlled adaptive evolution. History (2) Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems (2014 unpublished) This atoms to ecosystems model of ecological adaptations links nutrient-dependent epigenetic effects on base pairs and amino…

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Coherently organized healthy longevity (2)

August 1, 2020
James Kohl
biophotonics, Light Energy, microRNA editing, Physics, RNA interference, RNA–Mediated Epigenetic Heredity, What's in the News
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RNA-mediated.com Here you will find information that links physics, chemistry, and molecular epigenetics via RNA-mediated events such as the de novo creation of olfactory receptor genes in order to encourage a public discussion of a paradigm shift. Within 8 hours from the time I posted Coherently organized healthy longevity (1) to my blog site at RNA-mediated.com, Quanta Magazine regurgitated this claim from 1/3/19 Quantum error-correcting codes are essential for protecting information in quantum computers. They may also be responsible for…

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Coherently organized healthy longevity (1)

July 31, 2020
James Kohl
Alternative Splicings, Cytosis, Diseases & Disorders, Ecology, Model Organisms, RNA Directed, RNA interference, What's in the News
One Comment

A large-scale binding and functional map of human RNA-binding proteins [RBPs] 7/29/20 We describe the spectrum of RBP binding throughout the transcriptome and the connections between these interactions and various aspects of RNA biology, including RNA stability, splicing regulation and RNA localization. These data expand the catalogue of functional elements encoded in the human genome by the addition of a large set of elements that function at the RNA level by interacting with RBPs. Reported as: ENCODE consortium identifies RNA…

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pH-dependent viral latency (5)

June 5, 2020
James Kohl
Adaptations, biophotonics, Diseases & Disorders, Ecology, Nutrigenomics, RNA Directed, RNA interference, What's in the News
One Comment

Molecular and biochemical mechanisms of human iris color: A comprehensive review 6/2/20 MicroRNAs also affect melanocyte synthesis, which is usually affected by the downregulation of essential genes involved in pigmentation. Researchers from Iran linked light-activated microRNA biogenesis in plants to the expression genes that effect the number, size and/or the pH of pathways that influence melanin synthesis in the context of human iris color and human skin pigmentation via the L‐tyrosine amino acid precursor. The energy-dependent microRNA-mediated link from the…

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pH-dependent viral latency (2)

May 24, 2020
James Kohl
Adaptations, Alternative Splicings, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Model Organisms, Neuronal Plasticity, RNA Directed, RNA interference, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, What's in the News
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New vaccines protect against COVID-19 in non-human primates, study finds 5/20/20 See for comparison: Vaccines do not control pandemics (1) 5/15/20 I reiterate: Emergence of Human G2P[4] Rotaviruses in the Post-vaccination Era in South Korea: Footprints of Multiple Interspecies Re-assortment Events 4/18/18 Amino acid substitutions at these positions were found to be associated with an inability to serotype a strain and are responsible for antigenic changes48. Recently, amino acid substitutions in the three main antigenic regions, especially at positions 96…

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The microRNA-mediated future of humanity (3)

April 24, 2020
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, Nutrigenomics, Pharmacogenomics, Physics, RNA interference, What's in the News
No Comments

Light-activated microRNA biogenesis has been linked from the pheromone-controlled physiology of reproduction to healthy longevity via protection from the virus-driven degradation of messenger RNA in all living genera. On 4/21/20 that fact was misrepresented as: Coronavirus has mutated into at least 30 different strains, Chinese study finds. The report was based on this non-peer-reviewed paper Patient-derived mutations impact pathogenicity of SARS-CoV-2 We observed intrapersonal variation and 6 different mutations in the spike glycoprotein (S protein), including 2 different SNVs that…

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WHO’s ignorance: From roots to shoots (2)

March 24, 2020
James Kohl
Adaptations, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, Nutrigenomics, Pharmacogenomics, RNA interference, What's in the News
No Comments

WHO’s ignorance: From roots to shoots (1) Amino acid substitutions within or near the active site of the viral neuraminidase (NA) may affect influenza virus fitness. See: Neuraminidase inhibitor susceptibility and neuraminidase enzyme kinetics of human influenza A and B viruses circulating in Thailand in 2010–2015  The authors cite the World Health Organization’s Summary of neuraminidase amino acid substitutions associated with reduced inhibition by neuraminidase inhibitors” The summary is available as a pdf download. See also: Viral Factors Associated With…

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