It is perhaps easy to forget that we have co-evolved on this planet with micro-organisms, including bacteria, which may be either beneficial or harmful to us. Similarly, viruses cannot copy themselves without help from our cells. Without us, they simply wouldn’t exist.

Watch as science journalists change evolution to co-evolution and biodiversity is portrayed as co-speciation. Theorists who missed the paradigm shift continue their desperate attempts to regain credibility after decades of making ignorant claims about mutations, natural selection, and evolution.

The major antigenic changes of the influenza virus are primarily caused by a single amino acid near the receptor binding site.

Serious scientists believe that the energy-dependent physiology of reproduction in soil bacteria links the bull sperm microRNAome to microRNAs in breast milk that are essential for protection against virus-driven energy theft, and that the production of taxol from the bark of the Pacific yew tree links everything known about cell type differentiation in all living genera to the fact that ecological adaptation must protect species from virus-driven energy theft and genomic entropy.

Hsp 90: a Driver of Novelty in Evolution

Proteins leave the ribosome as long, linear chains of amino acids but they need to fold into complex three dimensional shapes in the extremely crowded environment of the cytoplasm.  Since protein misfolding can be disastrous for cells, proteins known as heat shock proteins (HSPs) have evolved to facilitate proper protein folding. Lindquist explains that sometimes the heat shock response becomes unbalanced resulting in human disease.

Energy-dependent protein folding is biophysically constrained by the availability of nutrients. Nutrient energy is the anti-entropic source for RNA-mediated amino acid substitutions that differentiate all cell types.

The claim that “…heat shock proteins (HSPs) have evolved to facilitate proper protein folding” eliminates virus-driven energy theft as the source of all pathology. If you are a biologically uninformed layperson who believes in neo-Darwinian pseudoscientific nonsense you will probably accept that claim.

For comparison, serious scientists are not likely to believe that proteins evolve themselves to facilitate proper protein folding. That is one of the most ignorant claims that has ever been made by an evolutionary theorist.

From 5 years ago: ‘Brain-eating amoeba’ claims second victim this month

If neo-Darwinian pseudoscientists knew anything about energy-dependent cell type differentiation, they might have prevented the tragic death of this victim, who was killed by the ability of the viruses in the amoeba to adapt under conditions that typically are biophysically constrained.

The integration of quantitative genetics, paleontology, and neontology reveals genetic underpinnings of primate dental evolution (open access)

The obvious link to the nutrient energy-dependent pheromone-controlled manifestation of teeth in the predatory nematode P. pacificus makes all other claims about dental evolution appear to be based on the pseudoscientific nonsense of neo-Darwinian theories. Teeth exemplify the obvious link between ecological variation and ecological adaptation that also links angstroms to ecosystems via metabolic networks and genetic networks in species from microbes to humans.

reported as: Quantitative genetics provides predictive power for paleontological studies of morphological evolution

A change in primate dental proportions observed in the fossil record could therefore be selectively linked to temperature’s effect on body size according to Bergmann’s rule (25), to precipitation’s effect on vegetation and diet (26), to resource competition from a newly evolved species (27), or to interspecific competition for mates and sexual dimorphism resulting from changes in habitat availability (28). Reconstructing historical patterns of selection fromthe fossil record can easily become a multivariate, multifactorial quagmire.

The only obvious solution to that problem is to claim that mutations somehow link natural selection to the evolution of a new species based on what is observed in the fossil record. This allows pseudoscientists to ignore all the experimental evidence that links energy-dependent changes from angstroms to ecosystems by protecting organized genomes from virus driven energy theft and genomic entropy.

Researchers discover that DNA naturally fluoresces

This research is described in the August 15 issue of the Proceedings of the National Academy of Sciences.

The article does not appear in the August 16 issue of the Proceedings of the National Academy of Sciences. (See the complaints from others in the comments at Phys.org)

It is likely that their results can be placed into the context of the most powerful refutation of neo-Darwinism that biologically uninformed theorists could ever have imagined.

At the same time theorists desperately attempt to revise past claims and make energy-dependent “co-speciation” the equivalent of “evolution,” what is known to serious scientists about hydrogen-atom transfer in DNA base pairs in solution will cause all serious scientists to laugh even harder at the pseudoscientific nonsense that was accepted by theorists.

Chemo in Pregnancy Could Lead to Early Menopause in Daughters

“In a study involving mouse tissue, we have shown that etoposide can damage the development of the ovaries while a fetus is in the womb. The drug affects the germ cells in the ovaries, which are the cells that give rise to eggs. This is important because it could mean that the fertility of the offspring could be affected in later life,” explained Spears.

The failure to link this example of transgenerational epigenetic inheritance of unrepaired DNA damage can be compared to facts about nutrient energy-dependent RNA-mediated DNA repair in the context of the physiology of reproduction, which links the bull sperm microRNAome to human brain development via what is known about Zika virus damage and microRNAs in breast milk.

What Your “Gut Feeling” Is Really Telling You

“Humans have trillions of microorganisms in our guts, and we have to be careful when activating antimicrobial defenses so that we mainly target potentially harmful microbes, without damaging our good bacteria, or even our own cells, in the process,” Aballay said. “The nervous system appears to be the perfect system for integrating all these different physiological cues to keep the amount of damage in check.”

The failure to link the gut microbiome from the innate immune system to supercoiled DNA in the human genome represents the failure of pseudoscientists to link anything known about energy-dependent RNA-mediated DNA repair and cell type differentiation to differences between healthy longevity and virus-driven pathology.

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