A cinematic approach to drug resistance

In a creative stroke inspired by Hollywood wizardry, scientists have designed a simple way to observe how bacteria move as they become impervious to drugs. The experiments are thought to provide the first large-scale glimpse of the maneuvers of bacteria as they encounter increasingly higher doses of antibiotics and adapt to survive—and thrive—in them.

My comment: The nutrient-dependent pheromone-controlled ecological adaptations were reported as if mutation-driven evolution of bacteria had occurred.

See for comparison: Published on 30 Mar 2016

The anti-entropic force of virucidal ultraviolet light links guanine–cytosine (G⋅C) Watson–Crick base pairing from hydrogen-atom transfer in DNA base pairs in solution to supercoiled DNA, which protects the organized genomes of all living genera from virus-driven entropy. For example, protection of DNA from permanent UV damage occurs in the context of photosynthesis and nutrient-dependent RNA-directed DNA methylation, which links RNA-mediated amino acid substitutions to DNA repair. In the context of thermodynamic cycles of protein biosynthesis and degradation, DNA repair enables the de novo creation of G protein coupled receptors (GPCRs). Olfactory receptor genes are GPCRs. The de novo creation of olfactory receptor genes links chemotaxis and phototaxis from foraging behavior to social behavior in species from microbes to humans. Foraging behavior links ecological variation to ecological adaptation in the context of this atoms to ecosystems model of biophysically constrained energy-dependent RNA-mediated protein folding chemistry. Protein folding chemistry links nutrient-dependent microRNAs from microRNA flanking sequences to energy transfer and cell type differentiation in the context of adhesion proteins, and supercoiled DNA that protects all organized genomes from virus-driven entropy.

See also: Evolutionary Rewiring

Strong selective pressure can lead to rapid and reproducible evolution in bacteria.

Serious scientists support their claims with experimental evidence of biologically-based cause and effect. In the context of weekend evolution, the claims can be linked to the claims of creationists.

See for comparison: Giant Petri Dish Displays Evolution in Space and Time

Re: “It’s a really amazing and easy way to show evolution in action to everyone,” she said, and to make abstract concepts such as evolution and mutation concrete.

They showed how ecological variation is linked from the innate immune system to supercoiled DNA, which protects all organized genomes from virus-driven entropy. Simply put, they linked nutrient-dependent quorum sensing to the physiology of pheromone-controlled reproduction in species from microbes to humans.

If they had showed evolution in action, their claims would link mutations to the weekend resurrection of the bacterial flagellum in Pseudomonas florescens, and they would refute every aspect of neo-Darwinian theory via the speed at which ecological adaptations in morphological and behavioral phenotypes occur.

See for comparison: Feedback loops link odor and pheromone signaling with reproduction

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