The 1902 definition of mutation by Hugo de vries can again be placed into the context of facts about energy-dependent RNA-mediated cell type differentiation and healthy longevity before anyone else attempts to redefine heredity. Hopefully, that will be done before anyone else from the CDC goes missing. The threat to thos who understands how top-down causation is linked to the transgenerational epigenetic inheritance by cell survival is severe because they have linked virus-driven energy theft from mutations to the death gene. For comparison, mathematical models link mutations to evolution.

Historical perspective:

De Vries’s theory was one of the chief contenders for the explanation of how evolution worked, leading, for example, Thomas Hunt Morgan to study mutations in the fruit fly, until the modern evolutionary synthesis became the dominant model in the 1930s. Somewhat ironically, the large-scale primrose variations turned out to be the result of chromosomal duplications (polyploidy), while the term mutation now generally is restricted to discrete changes in the DNA sequence.

Thomas Hunt Morgan won the Nobel Prize in Physiology or Medicine in 1933 for discoveries elucidating the role that the chromosome plays in heredity.[2]

See also: Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels (1990), which was co-authored by Michael Rosbash who shared the 2017 Nobel Prize in Medicine for development of the cryo-EM technology. Cryo-EM links energy-dependent changes in electrons to ecosystems via the physiology of reproduction and chromosomal rearrangements that biophysically constrain viral latency in all living genera.

See for comparison, this attack on my scientific credibility by P.Z. Myers: One crank dies, another rises to take his place

I wrote:

The proof of ecological variation that appears to refute the theory of evolution, which actually refutes itself, is that ecological adaptations occur too fast for mutations to compete with them as a source of anything but diseases and disorders.

Since December 25, 2017 I have been using my twitter account to reach a larger target audience at a pace of about 100,000 impressions each month.  For example, my top tweet in February got 12,500 impressions. I wrote:

I think the problem is why theorists placed their claims into the context of the emergence of energy and mutation-driven evolution. Sure that exemplifies idiocy, but it’s easy to understand without the metaphors. Complexity “just happens” — scientificamerican.com/article/the-su

See also:

See also: Ecological adaptation: A new definition of heredity (3)

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