Objection: In the law of the United States of America, an objection is a formal protest raised in court during a trial to disallow a witness’s testimony or other evidence which would be in violation of the rules of evidence or other procedural law.
Americanism (ideology) links the laws of United States of America to God’s “Laws of Biology.” Pseudoscientists violated the rules of evidence that link Darwin’s “conditions of life” from God’s “Laws of Biology” to all nutrient energy-dependent biophysically constrained pheromone-controlled biodiversity on Earth.
Laws of biology: why so few? (2010)
…every biological decision is optimal in a given environmental context. However, due to complex nature of biological organization it is difficult to think of a universal law or a theory in biology connecting all the levels, from atoms to ecosystems.
- In Section One, the focus is on links between atoms and ecosystems via amino acid substitutions. In Section Two, the focus is on examples of links across a continuum of nutrient-dependent, pheromone-controlled, epigenetically-effected, receptor-mediated ecological adaptations via amino acid substitutions and changes in the microRNA/messenger RNA balance.
- Nutrient-dependent pheromone-controlled ecological adaptations exemplify how sensing nutrients and secreting the metabolites of nutrients accomplishes different tasks. Efficient circuits enable the functional flexibility that is required in ever-changing ecologies that cause species diversity. Biophysical constraints on ecological adaptations are exemplified in physical proof which suggests that Kohl’s Laws of Biology (Kohl’s Laws) represent what Darwin called ‘conditions of life.’
Natural selection for nutrient energy-dependent codon optimality is exemplified in species from archaea to humans. See for example: Codon identity regulates mRNA stability and translation efficiency during the maternal-to-zygotic transition (2015)
The bias between codons or amino acids, and mRNA expression levels has been previously recognized across species and is thought to result from selection for efficient, accurate translation, and folding of highly expressed genes (Ikemura, 1982; Akashi, 1994; Akashi & Gojobori, 2002; Drummond & Wilke, 2008; Kudla et al, 2009; Novoa & Ribas de Pouplana, 2012). The amino acid optimality code (Fig 6) provides an alternative perspective on sequence changes between paralogs in evolution and human disease.
That perspective on sequence changes between paralogs in evolution and human disease placed endogenous RNA interference into the context of Intelligent Design after Darwin and all other serious scientists had linked it from sunlight to all biodiversity on Earth via their observations and experimental evidence of biologically-based cause and effect.
See for example: Nutrient-dependent/pheromone-controlled adaptive evolution: a model
…the model represented here is consistent with what is known about the epigenetic effects of ecologically important nutrients and pheromones on the adaptively evolved behavior of species from microbes to man. Minimally, this model can be compared to any other factual representations of epigenesis and epistasis for determination of the best scientific ‘fit’.
Wells recognizes that various well-established processes like alternative splicing and RNA editing often determine the amino acid sequence of proteins.
Like all pseudoscientists before him, Wells failed to recognize the most important fact of all. That fact was expressed in the context of the fact that gene expression is energy-dependent in DEPENDENCE OF RNA SYNTHESIS IN ISOLATED THYMUS NUCLEI ON GLYCOLYSIS, OXIDATIVE CARBOHYDRATE CATABOLISM AND A TYPE OF “OXIDATIVE PHOSPHORYLATION”(1964)
The synthesis of RNA in isolated thymus nuclei is ATP dependent.
The pseudoscientists that failed to acknowledge that fact are among the losers that were placed into the following perspective:
Nobody wants to belong to the party of losers. One of the best strategies in such a case is evidently an interpretation of the change as a gradual accumulation of knowledge while their work has always been at the cutting edge. — Kalevi Kull (2016)
The losers can now be recognized in the context of the failure to provide the free delivery of God’s “billion dollar baby” to healthcare practitioners. Simply put, many healthcare professionals were not told how to link energy from endogenous RNA interference (RNAi) to healthy longevity in all living genera. They were not told that natural selection for energy-dependent codon optimality and endogenous RNAi have always linked angstroms to ecosystems in all living genera via RNA-mediated amino acid substitutions in supercoiled DNA. Why didn’t all medical practitioners learn that supercoiled DNA protects all organized genomes from virus-driven energy theft and genomic entropy.
See for examples of what was missing:
RNAi has targeted exogenous genes in models of viral infection…
RNA-triggered gene silencing (1999)
Repetitive elements or endogenous viral elements can be targeted with engineered Cas+gRNA systems in microbes, plants, animals, or human cells to reduce deleterious transposition or to aid in sequencing or other analytic genomic/transcriptomic/proteomic/diagnostic tools (in which nearly identical copies can be problematic).
The other technology besides CRISPR gene editing, which is the subject of this post is called RNAi technology. See link in references below as to the differences between CRISPR & RNAi technologies.
…something went horribly wrong, they don’t really know what it was other than it failed, caused death of some patients and so they discontinued the experimental drug. This has an uncanny similarity to and is reminiscent of the Tryptophan disaster – GM Potato & Árpád Pusztai affair & the GM pea causes allergic reactions to name a few.
“Deep inside its labs, Monsanto is learning how to modify crops by spraying them with RNA rather than tinkering with their genes”
Spraying crops with RNA causes RNA interference in the same way that the CRISPR/Cas9 technology replaced virus-altered RNA interference via use of other viruses that caused the innate immune response to link amino acid substitutions to DNA repair if the missing amino acids were again made available. It is like fighting fire with fire, which sometimes works to extinguish the life of one fire that is out of control but does not prevent other fires from emerging and destroying other properties, or the same property at a later date. The ominous prophecies from the Holy Bible now loom larger if, like all other prophecies, they are correct. Those who survive the next viral apocalypse seem likely to live long enough to die a fiery death that clearly will be linked to the sun’s biological energy from the protection of supercoiled DNA that once helped to ensure our healthy longevity.
See for comparison: A Christian Worldview & Mental Health (2011)
Christian concern for the whole person includes both mind and body, so this volume encourages readers to think about theoretical and spiritual issues within Christian mental health care. Views are collected from various disciplines such as ethics, psychology, theology, counseling, and psychiatry. In its consideration of a Seventh-day Adventist spiritual identity in mental health theory and practice, this text will prove very valuable to mental health education.
The Christian worldview links what organisms eat to natural selection for energy-dependent codon optimality and healthy longevity, which links supercoiled DNA from the physiology of reproduction to all morphological and behavioral diversity in species from microbes to humans. The Christian worldview has typically been one in which peaceful coexistence is the desired goal. That goal is based on what is known about energy-dependent symbiosis and homeostasis in species from microbes to humans. The atheistic worldview is shared by proponents of Intelligent Design and others who are biologically uninformed. They seem to think that Darwin replaced the Laws of Biology, when what he repeated asserted was that “conditions of life” come first. Only pseudoscientists have continued to link mutations from natural selection to the evolution of one species from another across millions of years.
The pseudoscientists have organized a “March for Science” in an attempt to keep forcing their pseudoscientific nonsense on the biologically uninformed masses in the United States of American who were taught that they could break any of God’s Laws that they chose to break, after the Laws were broken by those who chose to believe in, and to teach, their ridiculous theories to several generations of children that grew up to become liberals.
But wait, here are a few more claims that can be placed into the context of the Laws of Biology, but not into the context of mutation-driven evolution.
Nutrient energy-dependent changes in the microRNA/messenger RNA link endogenous RNA interference to biophysically constrained biodiversity in nematodes that is exemplified in differences between C. elegans and P. pacificus, a predatory nematode with teeth. The physiology of reproduction is controlled by pheromones in all living genera and the pheromones link microRNAs from supercoiled DNA to chromosomal inheritance in different species.
See also from 2013: Extracellular Regulation
During Caenorhabditis elegans development, the hermaphrodite-specific neurons (HSNs) migrate and then extend axons toward their functional targets. Posttranslational modification of heparan sulfate proteoglycans are important for HSN development, and so Pedersen et al. (p. 1404) tested the effect of disrupting or reducing chondroitin and heparan sulfate synthesis during C. elegans development. The results suggest that proteoglycan biosynthesis is tightly regulated by a microRNA pathway to shape the cell surface glycosylation architecture required to direct neuronal migration.
This means the sex difference in cell types can be linked to the advent of sexual reproduction in yeasts via the conserved molecular mechanisms we detailed in the molecular epigenetics section of our 1996 Hormones and Behavior review. From Fertilization to Adult Sexual Behavior
See for comparison: Today on Darwin Day, Trey the Explainer Sends a Gift. He Power Owns Dr. Ben Carson! (Video)
The “Explainer” dismisses facts about energy-dependent endogenous RNA interference and pretends that the variants in the fossil record support the ridiculous theories of neo-Darwinian theorists. There is no way to explain his ignorance, or why he flaunts it.
Energy as information dictates gene expression in the context of established links from chirality to autophagy in species from microbes to humans.
All pathology is caused by virus-driven energy theft. The barrage of misinformation you are being subjected to is increasing each day.
also reported as:
Superspreader phages transfer drug resistance
Lucky for us, bacteriophages infect bacteria, not humans. That doesn’t mean they don’t have profound effects on us, however. A new report in the journal mBio from researchers at the University of Miami and the National Cancer Institute describes “superspreader” bacteriophages that promote DNA transfer from one bacterium to another – and some of this DNA codes for antibiotic resistance genes.