Evolution of stem cells traced in study of fossilized rodent teeth

Excerpt: “the mechanism that allowed the shift from longer teeth to continuously growing ones… probably linked to a regulatory element of DNA that activates the transcription of a gene or genes.”

My comment: Nutrient-dependent pheromone-controlled fixation of RNA-mediated amino acid substitutions links the epigenetic landscape to the physical landscape of DNA in the organized genomes of species from microbes to man via conserved molecular mechanisms of the biophysically constrained chemistry of protein folding. This was exemplified by the re-evolution of the bacterial flagellum “over-the-weekend.”

The claim that evolutionary pressure would require “…multiple steps that would take millions of years” for evolution of our teeth to occur is not supported by experimental evidence of biologically-based cause and effect in any species. See also: New Epigenetic Mark Found on Metazoan DNA

This “new” epigenetic mark is required to link cell type differentiation via amino acid substitutions from plants to algae, worms, flies, and primates via the biophysically constrained chemistry of nutrient-dependent RNA-mediated protein folding. The report that it is “new” actually attests to the fact that the mark has always been there. Obviously, it must have been there all along for ecological variation to lead to ecological adaptation via the conserved molecular mechanisms of cell type differentiation: RNA-directed DNA methylation and RNA-mediated amino acid substitutions.

Rather than address the experimental evidence that links “over-the-weekend” evolution to the complexity of the bacterial flagellum, evolutionary theorists continue their attacks on the credibility of serious scientists and science journalists who offer accurate representations of biologically-based cause and effect. For example:  Evolutionary resurrection of flagellar motility via rewiring of the nitrogen regulation system was published on February 27, 2015.  This attack on the credibility of Mae-Wan Ho and Suzan Mazur: was written by whyevolutionistrue and posted on April 12, 2015

the blind leading the blind about evolution

Excerpt 1)

Mae-Wan Ho is a scientist known, to me at least, for unproductive work: dissing GMOs and biotechnology and, especially, relentlessly attacking “neo-Darwinism”, the modern theory of evolution.

My comment: She is known to me for linking the sun’s biological energy from the de novo creation of amino acids to RNA-mediated amino acid substitutions that differentiate the cell types of all genera.

Excerpt 2)

Suzan Mazur: There’s a debate about whether viruses are alive or not. What position do you take?

Mae-Wan Ho: The moral of all that is that this DNA-centered view is really completely mistaken and outmoded. There is no DNA determinism. DNA or RNA does not equal life. They are kind of like memory molecules but the memory gets rewritten.

My comment: Evolutionary theorists do not address how memory is rewritten. The fact that the bacterial flagellum re-evolves means microbial cells contain instructions that enable the rewriting to occur when ecological variation requires change. The bacterial flagellum is a virus-driven ecological adaptation that links viral microRNAs to entropic elasticity and the anti-entropic epigenetic effect of nutrient-dependent microRNAs to RNA-mediated cell type differentiation via amino acid substitutions in species from microbes to humans.

See also: Retroviral influence on human embryonic development

Excerpt 1)

Viral RNAs were detected beginning at the 8-cell stage, through epiblast cells in preimplantation embryos, until formation of embryonic stem cells (illustrated).

My comment: The typical claim links the presence of viral RNAs across millions of years of evolution.

Excerpt 2)

There are over 500,000 endogenous retroviruses in the human genome, about 20 times more than human genes. They were acquired millions of years ago after retroviral infection. In this process, viral RNA is converted to DNA, which then integrates into cell DNA. If the retroviral infection takes place in the germ line, the integrated DNA may be passed on to offspring.

My comment: Given the fact that the bacterial flagellum re-evolved in four days, can the ridiculous theory that different species evolved during millions of years be linked to the presence of 500,000 endogenous retroviruses in the human genome, and detection in preimplantation embryos? That was a rhetorical question. Evolutionary theorists should think about facts in the context of Sulfur-cycling fossil bacteria from the 1.8-Ga Duck Creek Formation provide promising evidence of evolution’s null hypothesis. The facts that 1) some microbes did not evolve during 1.8 billion years and that 2) others re-evolved their flagellum in 4 days attests to the nonsense that evolutionary theorists have been taught to believe in.

See also: The Breakthrough Darwinists Missed: “Junk” DNA Isn’t Junk

Excerpt:

New discoveries vindicate the intelligent design theorists — and suggest evolutionary biologists may have lost precious time because of their assumptions about the origins of DNA.

My comment: No discoveries have ever vindicated the evolutionary theorists. That’s why they can only attack serious scientists. If they attempt to address the discovery that the bacterial flagellum re-evolved over-the-weekend or any other aspect of RNA-directed DNA methylation and RNA-mediated amino acid substitutions that differentiate the cell types of all individuals of all species in the context of the physiology of their reproduction, evolutionary theorists are faced with the lack of experimental evidence that has failed to support any of their ridiculous claims. For comparison, see Dobzhansky (1973) “…the so-called alpha chains of hemoglobin have identical sequences of amino acids in man and the chimpanzee, but they differ in a single amino acid (out of 141) in the gorilla” (p. 127).

For more information on the difference a single amino acid substitution makes in the context of RNA-mediated cell type differentiation in species from microbes to man, see:

Nutrient-dependent/pheromone-controlled adaptive evolution: a model

and

Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems,

which are summarized in this 5.5 minute-long video: Nutrient-dependent / Pheromone-controlled adaptive evolution: (a mammalian model of thermodynamics and organism-level thermoregulation)

 

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