Book recommendations: For non-technical representations of how nutritional epigenetics and pharmacogenomics are linked via ecological adaptations, see:
In his 1985 science fiction novel, linked above, Greg Bear included everything that is currently known to serious scientists about RNA-mediated amino acid substitutions and cell type differentiation in species from microbes to humans. He indirectly addressed the fact that the anti-entropic epigenetic effects of nutrients biophysically constrains cell type differentiation, which is limited by the physiology of reproduction. After the virus-like agents of change killed their first few hosts, the agents adapted in the context of symbiotic interactions. That is what most viruses are typically forced to do.
In his 1999 science fiction novel, linked above, Greg Bear linked the development of a new human subspecies via the pheromone-controlled physiology of their nutrient-dependent reproduction.
Reviewer’s comment: I’m not afraid of this concept. Bear goes a little further in suggesting that such change can occur over about a generation, an idea that might be a little too radical at the moment. However, he does mention data suggesting that fruitflies can adapt to a new environment in just a few generations of selection.
My comment: That suggestion might cause evolutionary biologists to fear comments from serious scientists about their “just so” stories that link mutations and evolution.
In his 2003 science fiction novel, linked above, Greg Bear linked pheromonal communication to unconscious affects on the sub-species human-specific behaviors.
Reviewer’s comment: Bear incorporates the new ‘fact’ that humans have some 30,000 genes into his definition of ‘genome’, accepting it as canon, but he rejects the less controversial (albeit possibly incorrect) ‘fact’ that we are not descended from the Neanderthals.
My comment: No experimental evidence of biologically-based cause and effect suggests that our organized genomes make us the descendants of Neanderthals, or any other primate. The experimental evidence shows that only a single amino acid substitution differentiates our cell types and the cell types of chimpanzees from those of gorillas. For example, the so-called alpha chains of hemoglobin have identical sequences of amino acids in man and the chimpanzee, but they differ in a single amino acid (out of 141) in the gorilla. ( p. 127)
In our 1995/2002 non-technical representation of how chemical ecology links pheromones to biodiversity, the late From Fertilization to Adult Sexual Behaviorand I took advantage of his exceptional teaching abilities, and delivered our message about how biodiversity arose outside the context of ridiculous theories. In more technical problems, others have helped me to present a much broader overview of biologically-based cause and effect than I could ever have done in my monographs. See for example:
Greg Bear has continued to acknowledge our correspondence during the years he developed his extremely original ideas from the early 1980’s and incorporated into his 1999 and 2003 novels. Recently, he agreed to let me post “The Darwin Code: Intelligent Design without God” to my domains.
When I realized how close others were to unknowingly revealing or pretending to reveal what Greg Bear had already revealed, I established this domain and this FB group. Greg Bear remains one of the few supporters of my representations of how the physiology of RNA-mediated cell type differentiation links ecological variation and pheromones to biophysically constrained biodiversity in species from microbes to humans. Many others have fallen nearly 30 years behind the data. See for example: RNA-mediated gene duplication: the rat preproinsulin I gene is a functional retroposon.
It has become apparent that non-scientists are going to continue to complete the paradigm shift that Greg Bear started.
See for example of what another writer has done:
From the book previews, it appears that Perry Marshall also links viruses to the amino acid substitutions that differentiate the cell types of all genera. I ordered his book today. It will be interesting to see if he links pheromones to biophysically constrained cell type differentiation via the physiology of reproduction in species from microbes to humans, like Greg Bear began to do in 1985.
See for comparison the horrid misrepresentations of everything known to serious scientists about biologically-based RNA-mediated cause and effect in:
Richard L. Doty claims that mammalian pheromones do not exist.
Masatoshi Nei concluded that “…genomic conservation and constraint-breaking mutation is the ultimate source of all biological innovations and the enormous amount of biodiversity in this world. (p. 199)”
My comment: If you are interested in learning more about ecological speciation, and decide to buy any of these books, please help support my efforts by purchasing them from the links provided on this site. Unlike Richard L. Doty and Masatoshi Nei, serious scientists are not supported by the evolution industry and must rely on support from others who are outside that industry and the big bang cosmology industry. Thanks to Greg Bear for his ongoing support of the ideas he began to integrate in attempts to reach people who might be willing to help serious scientists who are still Combating Evolution to Fight Disease
The evolutionary biologist Theodosius Dobzhansky famously noted that “nothing in biology makes sense except in the light of evolution,” but perhaps, too, “nothing in evolution makes sense except in the light of biology.” Although the latter might be an exaggeration, an important gap is being filled by molecular understanding of the genesis of variation that confers the ability to evolve.
The genesis of variation that confers the ability to evolve is nutrient-dependent and RNA-mediated via fixation of amino acid substitutions in the cell types of all genera via their physiology of reproduction.