From optoribogenetics to HelioRiboGenetics (2)

By: James V. Kohl | Published on: October 5, 2020

See first: From optoribogenetics to HelioRiboGenetics (1)
For consistency see Abcam’s: Spotlight on Neuroscience [and the 2020 Nobel Prize for Physiology or Medicine]

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Chronic virus-driven inflammation perturbs epigenetic effects on energy-dependent microRNA-mediated autophagy, which prevents neurodegeneration.

Attempts to discredit Judy A. MIkovits for her role in linking God’s Creation of UV light and water to energy-dependent microRNA-mediated RNA interference, which is the patented cure that links light-activated carbon fixation to prevention or effective treatment of all virus-driven pathology via autophagy, worked well before first author, Harvey J. Alter, Charles M. Rice, and Michael Houghten shared the 2020 Nobel Prize in Physiology or Medicine.

For a historical perspective, see the article Harvey J. Alter co-authored with Judy Mikovits : A Multicenter Blinded Analysis Indicates No Association between Chronic Fatigue Syndrome/Myalgic Encephalomyelitis and either Xenotropic Murine Leukemia Virus-Related Virus or Polytropic Murine Leukemia Virus 9/18/12

Together, Harvey J. Atler et al., (2012) linked God’s Creation of UV light and water from microRNA biogenesis to RNA interference and effective treatment of all virus-driven pathology in: Circulating let‐7 levels in plasma and extracellular vesicles correlate with hepatic fibrosis progression in chronic hepatitis C 5/26/16

The goal of this study was to determine whether an association exists between circulating microRNA (miRNA) levels and disease progression in chronic hepatitis C (CHC),

See also: Circulating let-7 Levels in Serum Correlate With the Severity of Hepatic Fibrosis in Chronic Hepatitis C

KEYWORDS extracellular vesicles, hepatic fibrosis, hepatitis C virus, let-7 microRNA

But Alter’s epic failure to link energy-dependent cause and effect to all biodiversity was manifested in:  MicroRNA Involvement in Signaling Pathways During Viral Infection and MicroRNAs organize intrinsic variation into stem cell states

…the results presented here suggest that naturally arising cell-to-cell variation, sometimes described as stochastic fluctuation, is in fact coherently organized biology.

The virus-driven degradation of messenger RNA prevents the links from quantum coherence to coherently organized biology.
When will biologically uninformed theorists, and Nobel Laureates with limited expertise across disciplines admit that they knows nothing about biophysically constrained viral latency compared to anyone who has linked God’s Creation of energy-as-information from quantum coherence to coherently organized biology across kingdoms via the physiology of reproduction.
For instance, see:

Disabled were walking again, the blind were seeing again, and the death rose from the grave. 2013 was the year in which prophesy from the bible became reality. — De Correspondent dec 2013

For comparison: Charles M. Rice linked the UV light-activated assembly of the microRNA-RNA-peptide nanocomplex from quantum coherence to coherently organized biology in 18 published works since 2005 See: microRNA and Rice and CM
For example: Control of human hemoglobin switching by LIN28B-mediated regulation of BCL11A translation 1/20/20

Our results reveal a previously unappreciated mechanism underlying human hemoglobin switching that illuminates new therapeutic opportunities.

More then 1800 human hemoglobin variants link what people eat to the pheromon-regulated genetic processes of reproduction. See: HbVar: A Database of Human Hemoglobin Variants and Thalassemias. 
Differences in primates have been linked to ethnicity via food energy-dependent pheromone-controlled feedback loops. For example,  2004 Nobel Laureate in Physiology or Medicine, Linda Buck linked quantum coherence to coherently organized biology in mammals via publication of Feedback Loops Link Odor and Pheromone Signaling with Reproduction
Wen Zhou’s group linked quantum coherence to coherently organized biology in all living genera across the space-time continuum via our visual perception of energy and mass. See: Olfaction Warps Visual Time Perception
The problem for all neo-Darwinian theorists, Big Bang cosmologists, Democrats, atheists and Communists who have not linked quantum coherence to coherently organized biology is that “Evolutionists Cannot Account for the Origin of the Sense of Smell
The problem got worse when Michael Houghton obfuscated optoribogenetic and helioribogenetic facts about energy-dependent RNA interference via his report on magical changes in the ether-à-go-go related gene 1 (hERG1) channel and virus-driven pathology. 
See: A structure-based computational workflow to predict liability and binding modes of small molecules to hERG 10/1/20

…we utilize the recent cryo-EM structure of the hERG channel and describe an integrated computational workflow to characterize different drug-hERG interactions. The workflow employs various structure-based approaches and provides qualitative and quantitative insights into drug binding to hERG.

Whether of not you listened to Ben Feringa’s 2018 presentation on light-activated nanotechnology, you should have by now learned that all structure-based approaches start with the light-activated assembly of the microRNA-RNA-peptide nanocomplex, and God’s Creation of energy-as-information must be linked to biophysically constrained viral latency via the Structural diversity of supercoiled DNA.
For recent updates to Ben Feringa’s predictive works, see:
Self-Assembly of Photoresponsive Molecular Amphiphiles in Aqueous Media 9/16/20
Here, we discuss the design of photoresponsive molecular amphiphiles, their self-assembled structures in aqueous media and at air-water interfaces, and various approaches to arrive at adaptive and dynamic functions in isotropic and anisotropic systems,
All-Photochemical Rotation of Molecular Motors with a Phosphorus Stereoelement 9/21/20

…we report three new second-generation molecular motors featuring a phosphorus center in the lower half, which engenders a unique element of axial chirality. These motors exhibit unusual behavior, in that all four diastereomeric states can interconvert solely photochemically.

The fact that these phosphorus-dependent states interconvert solely photochemically was presciently predicted in McEwen et al., (1964) Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation”

The synthesis of RNA in isolated thymus nuclei is ATP dependent.

May God help us all if the 2020 Nobel Laureates in Physics (10/6/20) and in Chemistry (10/7/20) have not learned how to link His Creation of UV light and water to biophysically constrained viral latency and all biodiversity on Earth via oxidative phosphorylation, the physiology of reproduction, and Biblical Prophesy, which links optoribogenetics to HelioRiboGenetics and all Genotypes.


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