God’s microRNA-mediated Creation of genotypes (2)

See also: MiR-125b regulates the differentiation of hair follicles in Fine-wool Sheep and Cashmere goats by targeting MXD4 and FGFR2 9/6/21

If you can’t link this to chromosomal rearrangements and sympatric speciation in species from flies to labradoodles, you haven’t played the STEM toy for ages 14+ “Genotype.”

One step back: Viral miRNA adaptor differentially recruits miRNAs to target mRNAs through alternative base-pairing 9/20/19
The authors link single nucleotide polymorphisms (SNPs) in microRNAs from alternative base-pairing to energy-dependent biophysically constrained viral latency, or from the virus-driven degradation of messenger RNA to all pathology across kingdoms.
The facts about energy-dependent changes in SNPs in microRNAs were also reviewed in the context of biophysically constrained autophagy in Topoisomerase IIα represses transcription by enforcing promoter-proximal pausing 4/13/21
This was reported on 9/4/21 as: DNA Supercoiling: DNA Structure Itself Is Involved in Genome Regulation

…this type of regulation occurs mainly in specific genes that are massively activated (in the order of a hundred-fold) in a few minutes in response to different types of stimuli like cellular stress, cell division signals, hormones or neuronal activation.

The chapter on Pheromones from Stress Science: Neuroendocrinology linked the activation of c-FOS to biophysically constrained biodiverisity in all jawed vertebrates via DNA supercoiling by starting with activation of “early genes.”

…c-FOS [whose codified protein is involved in cell proliferation] silencing them and creating a topological context that facilitates rapid activation to respond quickly to stimuli,” says Cortés.

Achiral glycine in position 6 of the GnRH decapeptide is the link from olfaction and pheromones to prevention of stress-linked virus-driven pathology. See: Feedback loops link odor and pheromone signaling with reproduction (2005)

Indications that GnRH peptide plays an important role in the control of sexual behaviors suggest that pheromone effects on these behaviors might also involve GnRH neurons.

The control of sexual behaviors was also linked to our visual perception of energy and mass across the space-time continuum in Olfaction Warps Visual Time Perception 3/17/17

These findings point to a neuronal network in the right temporal cortex that executes flexible temporal filtering of upstream visual inputs based on olfactory information. Moreover, they collectively indicate that the very process of sensory integration at the stage of object processing twists time perception, hence casting new insights into the neural timing of multisensory events.

Evolutionary theorists and Big Bang cosmologists got caught denying everything known about RNA processing and post transcriptional gene control.
See: Modern Genetics & Biotechnology 7/19/21 This diagram comes from a book chapter in Molecular Cell Biology. See page 324.

It’s a partial and pitiful representation of this energy-dependent pheromone-regulated mammalian model.

Nutrient-dependent/pheromone-controlled adaptive evolution: a model 6/14/13