Cell diversity and network dynamics in photosensitive human brain organoids

…neuronal activity within organoids could be controlled using light stimulation of photosensitive cells, which may offer a way to probe the functionality of human neuronal circuits using physiological sensory stimuli.

They are not going to tell anyone that these findings link the speed of light on contact with water to the energy-dependent physiology of reproduction in all living genera because the physiology of reproduction is nutrient-dependent and pheromone-controlled. Everyone knows that fact is a neo-Darwinian theory killer, and they do not want their ridiculous theories to die.

But see:

RNA biosynthesis is ATP-dependent in Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation” (1964)

The synthesis of RNA in isolated thymus nuclei is ATP dependent.

Isolated thymus nuclei transport amino acids into an intranuclear pool by a process which seems to depend on energy from nuclear ATP synthesis (20).

The energy from nuclear ATP synthesis links the creation of sunlight to all biophysically constrained biodiversity via the effects of virucidal ultraviolet light on microRNA biosynthesis. Without sunlight and the energy-dependent synthesis of microRNAs, there would be no messenger RNA and no energy-dependent / ATP-dependent transport of  amino acids.

(Note for theorists: No experimental evidence of biologically-based cause and effect suggests that sunlight created itself or that the anti-entropic energy of sunlight is not required to link what organisms eat and their pheromone-controlled physiology of reproduction to energy-dependent variants in supercoiled DNA. The energy-dependent biophysically constrained variants link chirality and autophagy from energy-dependent changes in the microRNA/messenger RNA balance and all biodiversity.)

Theorists who do not understand how to link the creation of sunlight to ATP and all energy-dependent biodiversity may need to examine the extant peer-reviewed literature and compare what is known to serious scientists with their ridiculous theories.

See for example: Mutation-Driven Evolution (2013/06/14)

(1) Mutation is the source of all genetic variation on which any form of evolution is dependent. Mutation is the change of genomic structure and includes nucleotide substitution, insertion/deletion, segmental gene duplication, genomic duplication, changes in gene regulatory systems, transposition of genes, horizontal gene transfer, etc. (2) Natural selection is for saving advantageous mutations and eliminating harmful mutations. Selective advantage of the mutation is determined by the type of DNA change, and therefore natural selection is an evolutionary process initiated by mutation. It does not have any creative power in contrast to the statements made by some authors.” (p. 196)

That is a ridiculous theory. See for comparison:

Biophotons: The Human Body Emits, Communicates with, and is Made from Light [not peer reviewed]

A photon–photon quantum gate based on a single atom in an optical resonator

Hard Two-Photon Contribution to Elastic Lepton-Proton Scattering Determined by the OLYMPUS Experiment

Summary from: What is Life? (1944) reprint edition

How often do we still hear that quantum effects can have little relevance in the study of biology, or even that we eat food in order to gain energy? — Roger Penrose 8 August 1991

See for comparison: Bonobo anatomy reveals stasis and mosaicism in chimpanzee evolution, and supports bonobos as the most appropriate extant model for the common ancestor of chimpanzees and humans

Reported as: Study finds bonobos may be better representation of the last common ancestor with humans than common chimpanzees April 29, 2017

See: My discussion attempt unless my comments have already been deleted.

See for support of the claim that we must eat to gain the energy that is required for microRNA biosynthesis and the links from messenger RNA to healthy longevity. Without food, virus-driven energy theft clearly links the degradation of messenger RNA from mutations to all pathology in all living genera. Without proper nutrition, the production of species-specific pheromones may lead to the transgenerational epigenetic inheritance of virus-driven energy theft. That fact has been established in the peer-reviewed literature during the past decade.

Today was the first day in several weeks that my PubMed “microRNA” alert did not return information on biophysically constrained RNA-mediated cell type differentiation.

See for comparison: MicroRNA From 2008/01/01 to 2012/10/12 Items: 1 to 20 of 17489

My presentation from 2012/10/12 was published on 2012/10/19 to a preprint site: Human pheromones and nutrient chemicals: epigenetic effects on ecological, social, and neurogenic niches that affect behavior [not peer reviewed]

Abstract

A systems biology approach to disease prevention and pharmacogenomics stresses the need to examine healthy behavioral development by including interactions among the evolved gene, cell, tissue, organ, organ-system pathway. This pathway links the epigenetic effects of nutrient chemicals and pheromones directly to the organization and activation of behavior in species from honeybees to humans.

Neuroscientifically established epigenetic effects of sensory input on hormones that affect behavior suggest that this mixture of human pheromones causes changes in ecotypically organized neural pathways that directly link nutrient chemicals and social niche construction to 1) neurogenic niches, 2) the molecular biology of evolved neural circuitry, 3) genetically predisposed physiological changes, and to 4) unconscious effects on behavior in species from invertebrates to mammals.

See for comparison Epub 2012 Oct 23.: The epigenetic potentials of dietary polyphenols in prostate cancer management.

See also: MicroRNA From 2013/06/14 to 2017/04/29 Items: 1 to 20 of 36632

Published 2013/6/14 Nutrient-dependent/pheromone-controlled adaptive evolution: a model.

Excerpt:

Moving forward

Evidence from genome-wide analysis suggests that polymorphisms cause alterations in neural connections and signaling in olfactory pathways, which contribute to natural variation in olfactory perception in flies (Swarup et al., 2013). That evidence links olfactory/pheromonal input to genetically predisposed species-specific behavior via previously unmodeled epistatic interactions that must occur throughout the lifecycle transitions of all organisms. Thus, the epigenetic ‘tweaking’ of the immense gene networks that occurs via exposure to nutrient chemicals and pheromones can now be modeled in the context of the microRNA/messenger RNA balance, receptor-mediated intracellular signaling, and the stochastic gene expression required for nutrient-dependent pheromone-controlled adaptive evolution. The role of the microRNA/messenger RNA balance (Breen, Kemena, Vlasov, Notredame, & Kondrashov, 2012; Duvarci, Nader, & LeDoux, 2008; Griggs et al., 2013; Monahan & Lomvardas, 2012) in adaptive evolution will certainly be discussed in published works that will follow.

From 2014/04/11 to 2017/04/29 Items: 1 to 20 of 29855

Nearly 30,000 more published works have been linked to the claims in The epigenetic potentials of dietary polyphenols in prostate cancer management and the claims in Cell diversity and network dynamics in photosensitive human brain organoids

Today, April 29, 2017 is the first day my alert for “New citations to works that mention microRNA” did not retrieve any items

Sent on Saturday, 2017 April 29 Search: microRNA Items: 1 to 20 of 60216

Your search did not retrieve any items.

Has someone stopped the flow of information about how the energy of sunlight links energy as information to all biodiversity via the physiology of reproduction? Alternatively, is the Trump administration prepared to shove the concept of energy as information down the throat of everyone who participated in the “March for Science?”

Or, come Monday, will the floodgates be opened again so that each additional peer-reviewed article that mentions the term “microRNA” targets another ridiculous theory for a slow death by drowning in information.

See also: Facebook Admits It’s Being Used by Political Actors to Manipulate Opinion

I published a series of blog posts about “False Flag Terrorism” when I realized that secular humanists and other atheists were too well organized for comparison to serious scientists who were Combating Evolution to Fight Disease. Cori Bargmann recently announced that the Chan Zuckerberg Initiative will help to fund a preprint server BioRxiv. The plan is to use the accurate dissemination of facts about biophysically constrained RNA-mediated cell type differentiation to continue refuting every aspect of neo-Darwinian nonsense that has ever be touted by biologically uninformed theorists. The Trump administration may never be credited with this plan, but serious scientists recognize the pattern of his actions. That’s because serious scientists are taught to recognize patterns rather than accept ridiculous theories that randomness and entropy cause everything on Earth to automagically occur.

The voice of FB in the context of editorial review comes through loud and clear. Can you hear the Zuckerberg’s now?

BioRxiv preprint server gets cash boost from Chan Zuckerberg Initiative

How will pseudoscientists stop the flow of information from Facebook and the BioRxiv preprint server? What will happen to the claims of pseudoscientist like this claim?

 

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