Origins of modern human ancestry 2/10/21
…no specific point in time can currently be identified at which modern human ancestry was confined to a limited birthplace…
This was reported as: On the origin of our species
“…neither the genetic or fossil record have so far revealed a defined time and place for the origin of our species.”
The frequency of the human-specific EDAR V370A allele appears to be uniquely elevated in North and East Asian and New World populations due to a bout of positive selection…
The link from positive selection for food to healthy longevity across continents can be compared to the virus-driven creation of the cell death gene, which was discovered in the late 1990’s and reported in 2011 as Reduced expression of brain-enriched microRNAs in glioblastomas permits targeted regulation of a cell death gene
…we demonstrated that neuronally differentiated SH-SY5Y cells transduced with the miRNA-regulated HSV-TK vector are protected from killing by expression of endogenous miR-128. Together, these results provide an in-depth analysis of miRNA dysregulation in glioblastoma and demonstrate the potential utility of these data in the design of miRNA-regulated therapies for the treatment of brain cancers.
Subsequently, Latency-Associated Transcript-Derived MicroRNAs in Herpes Simplex Virus Type 1 Target SMAD3 and SMAD4 in TGF-β/Smad Signaling Pathway 2/6/21 and Regulation of host and virus genes by neuronal miR-138 favours herpes simplex virus 1 latency 2/8/21 reintroduced the claims from RNA-Guided Human Genome Engineering.
Nothing new about biophysically constrained cell type differentiation was added to claims that were contextualized in Learning from Bacteria about Natural Information Processing 10/15/09 and in MicroRNA-based regulation of epithelial–hybrid–mesenchymal fate determination 11/5/13
However all intelligent people still know this:
Nobody wants to belong to the party of losers. One of the best strategies in such a case is evidently an interpretation of the change as a gradual accumulation of knowledge while their work has always been at the cutting edge. — Kalevi Kull
Researchers from Australia, USA, Iran, & Saudi Arabia linked Trump’s Impeachment Trial outcome to:
The paucity of the innate human inhibitory microRNAs to bind to leader sequence of SARS-CoV-2…” [and] …high replication in infected human cells.
If Trump is impeached that fact will suggest the authors of Regulation of host and virus genes by neuronal miR-138 favours herpes simplex virus 1 latency 2/8/21 know what they did to alter the course of history by limiting the dissemination of accurate information about microRNAs.
The accurate information probably would have altered he results of the 2021 US Presidential election because on 4/23/20 President Donald J. Trump linked God’s Creation of sunlight and humidity to constraints on coronavirus pathology.
He claimed that sunlight and humidity can weaken the coronavirus, and Jonathan Reiner said “…there’s no medical basis for Trump’s statements about sunlight.”
Trump was obviously right and biologically uninformed science idiots such as Reiner have always been wrong. Intelligent people now know that Schrödinger (1944) established the medical basis for Trump’s statement and the claims in Seeking the foundations of cognition in bacteria: From Schrödinger’s negative entropy to latent information 1/1/06
…it is widely accepted that there is no need for some unknown laws of physics to explain cellular ontogenetic development. We take a different view and in Schrödinger’s foot steps suggest that yet unknown physics principles of self-organization in open systems are missing for understanding how to assemble the cell’s component into an information-based functioning “machine”.
It is obvious that Trump and others like him know that the light-activated assembly of the microRNA-RNA-peptide nanocomplex links carbon fixation to protonated RNA interference via diet-driven microRNA biogenesis and changes to organized genomes, which have always been biophysically constrained by Peptide synthesis at the origin of life 11/13/20
See for comparison: A universal trend of amino acid gain and loss in protein evolution 2/10/05
Amino acid composition of proteins varies substantially between taxa and, thus, can evolve.
It is equally obvious that claims like this one are false claims. Unfortunately, the majority of Americans do not know enough to have a valid opinion about the origin of life or how it is biophysically constrained by peptide synthesis.
On 2/3/07, Tumpey et al., published A two-amino acid change in the hemagglutinin of the 1918 influenza virus abolishes transmission. On 10/13/11, a follow-up was published as Differential microRNA expression and virulence of avian, 1918 reassortant, and reconstructed 1918 influenza A viruses
When Koel et al., published Substitutions Near the Receptor Binding Site Determine Major Antigenic Change During Influenza Virus Evolution on 11/22/13, it became clear that
…major antigenic change can be caused by single amino acid substitutions.
On 4/23/20 Trump linked God’s Creation of sunlight and humidity to the weakening of coronavirus pathology and the end of the pandemic via genetic processes that link two food energy-dependent pheromone-constrained amino acid substitutions from the weekend resurrection of the bacterial flagellum in Evolutionary resurrection of flagellar motility via rewiring of the nitrogen regulation system 2/27/15 to the Resurrection of Jesus Christ via the claims of Chemistry Nobel Laureate, Bernard Feringa.
See: Dynamic control of chirality and self-assembly of double-stranded helicates with light 11/7/16 and this claim from
Disabled were walking again, the blind were seeing again, and the death rose from the grave. 2013 was the year in which prophesy from the bible became reality. — De Correspondent dec 2013
Therefore, it is obviously the God of Abraham who is being impeached via fake news and the complaints of Democrats, liberals, government subsidized academics, Communists, conspiracy theorists, and other atheists.
Impeaching Trump is akin to impeaching the God of Abraham for claiming that He Created sunlight and humidity because Trump linked that fact to the end of the coronavirus pandemic. So did researchers from Iran, Israel, and Korea in thousands of published works that support the claims from Biblical Genesis via the microRNA-mediated prevention of virus-driven diseases across kingdoms and the pH-dependent physiology of reproduction in soil bacteria and plants.
The claim that the Majority of Americans say Trump should be convicted, barred from holding federal office in impeachment trial: POLL 2/7/21, is a stupid false claim based on ignorance that the ignorant people who make such claims think will be accepted by the ignorant masses.
When the ignorant masses inform themselves, they will wish they had a leader like Donald J. Trump to help protect them from the public health fascists who have placed their billion dollar baby in therapy on hold until after they make billions to trillions more dollars by eliminating the individual liberties of patriots who do not read science articles like this Get Well in the RNAi Way-RNAi, A Billion Dollar Baby in Therapy 3/3/16 but finally realize
RNAi has targeted exogenous genes in models of viral infection…”
and that naturally occurring fact has been patented.
This article is from 11/19/18. See for comparison: The vibrational theory of olfaction for the win 10/31/17 and stop asking questions that have already been answered by intelligent serious scientists.
…an intrinsic covalently-bonded chromophore is spontaneously constructed from the side chains of the tripeptide Ser65-Tyr66-Gly67.
Covalently-bonded chromophores do not spontaneously construct themselves. Energy-dependent changes in peptides that were synthesized at the origin of life are required.
Circle back on this claim: Peptide synthesis at the origin of life 11/13/20 and link it from the 10-part series: The eternal significance of microRNAs (10) to the 10-part series: The microRNA-mediated future of humanity (10)