Light ‘drives’ adaptation; nothing ‘drives’ evolution
(click to enlarge)
Codon identity regulates mRNA stability and translation efficiency during the maternal‐to‐zygotic transition
Abstract: Cellular transitions require dramatic changes in gene expression that are supported by regulated mRNA decay and new transcription. The maternal-to-zygotic transition is a conserved developmental progression during which thousands of maternal mRNAs are cleared by post-transcriptional mechanisms. Although some maternal mRNAs are targeted for degradation by microRNAs, this pathway does not fully explain mRNA clearance. We investigated how codon identity and translation affect mRNA stability during development and homeostasis. We show that the codon triplet contains translation-dependent regulatory information that influences transcript decay. Codon composition shapes maternal mRNA clearance during the maternal-to-zygotic transition in zebrafish, Xenopus, mouse, and Drosophila, and gene expression during homeostasis across human tissues. Some synonymous codons show consistent stabilizing or destabilizing effects, suggesting that amino acid composition influences mRNA stability. Codon composition affects both polyadenylation status and translation efficiency. Thus, the ribosome interprets two codes within the mRNA: the genetic code which specifies the amino acid sequence and a conserved “codon optimality code” that shapes mRNA stability and translation efficiency across vertebrates.
See also: Biological causal links on physiological and evolutionary time scales
Excerpt:
Occam’s Razor – the problem solving principle in philosophy that suggests that the theory with fewest assumptions should be preferred at first – could be helpful here in judging each potential causal direction. For example in the gene duplication and genetic dispensability problem presented above, the evolutionary causal effect requires the extra assumption that dispensable genes are more likely to undergo gene duplication during evolution; this is non-trivial.
My comment: Pseudoscientists have trivialized the link from the speed of light on contact with water to the de novo creation of nucleic acids and all biodiversity, which links the creation of the innate immune system to supercoiled DNA. Science journalists report the trivialization in articles like this.
See: Do genomic conflicts drive evolution?
My comment: Nothing “drives” evolution across two billion years. Pennisi is in rare form.
She reports this:
Two billion years ago, an early cell swallowed an energy-producing microbe, giving birth to the mitochondria that are the hallmarks of all eukaryotes, from protists to people. Evolutionary biologists now think that was just the start of the influence that the cell’s “powerhouses” have on the tree of life.
In the same context, she reports:
…evidence that natural selection boosts mutation rates in the nucleus, apparently to keep up with mitochondrial evolution.
See for comparison: Virus-driven energy theft has been linked to all pathology in Epigenetics and Genetics of Viral Latency.
Excerpt:
…viral latency is responsible for life-long pathogenesis and mortality risk…
My comment: All serious scientists know that ecological variation must be linked to nutrient energy-dependent RNA-mediated ecological adaptation via biophysically constrained protein folding chemistry in all living genera. Only pseudoscientists and science journalists continue to report results in the context of two billion years of mutations, natural selection, and evolution.
See also: Inching toward the 3D genome; All in the (bigger) family — both articles were written by Pennisi, and the links are to my comments on the articles
See also: Combating Evolution to Fight Disease
My comment: Science journalists like Pennisi are supporting neo-Darwinian nonsense each time they report research in the context of two billion years of evolution.
See: Sulfur-cycling fossil bacteria from the 1.8-Ga Duck Creek Formation provide promising evidence of evolution’s null hypothesis
Excerpt:
…we interpret the striking similarities in organismal morphology, community structure, habitat, and evident physiology between the ancient and modern sulfur-cycling biotas as evidencing stasis resulting from adaptation to a physically quiescent subseafloor environment that has remained essentially unchanged over billions of years.
See for comparison: Evolutionary resurrection of flagellar motility via rewiring of the nitrogen regulation system
Excerpt:
A central process in evolution is the recruitment of genes to regulatory networks. We engineered immotile strains of the bacterium Pseudomonas fluorescens that lack flagella due to deletion of the regulatory gene fleQ. Under strong selection for motility, these bacteria consistently regained flagella within 96 hours via a two-step evolutionary pathway.
My comment: Compare the bacteria that recruited genes to re-evolve their flagellum via a two-step evolutionary process to the lack of any evolutionary process in the bacteria living in ocean sediments. What was the two-step evolutionary process that was required for the weekend evolution of the bacterial flagellum? Why did nothing change in the other bacteria for ~ 2 billion years? If you ask answers to the right questions, you will find that theories about mutations, natural selection, and evolution have no explanatory power.
See: Mutation-Driven Evolution
Conclusion:
… genomic conservation and constraint-breaking mutation is the ultimate source of all biological innovations and the enormous amount of biodiversity in this world. In this view of evolution there is no need of considering teleological elements (p. 199).
My comment: In that view of evolution, there is no need to consider anything except the ridiculous conclusion, which can be placed into the context of what serious scientists can see. Occam’s razor suggests that all serious scientists should view ecological variation in the context of observed ecological adaptation. If they cannot see that their observations should be placed into the context of what is known about biologically-based cause and effect, they may need to start looking under the light.
See for example: Gen9 “Our Founders “
The founders of Gen9 include people who are likely to know that femotosecond blasts of UV light are linked to RNA-mediated DNA repair of all virus-driven pathology via energy-dependent changes in base pairs and RNA-mediated amino acid substitutions. Unfortunately, most people cannot see how that fact is connected to this fact:
My comment: Perhaps people should open their eyes; look up; and see the light. Quantized energy is difficult to ‘see’ if you live and die in the dark.
Schrodinger (1944) and
Dobzhansky (1973) reported what they saw. The links open the pdf of Schrodinger’s book “
What is Life ?” and Dobzhansky’s classic
Nothing in Biology Makes Any Sense Except in the Light of Evolution .
In the forward to the reprint of “
What is Life?” Roger Penrose asks:
“How often do we still hear that quantum effects can have little relevance in the study of biology, or even that we eat food in order to gain energy?”
Others still report that learning more about mutations and natural selection is the key to understanding how evolution occurs across millions of years — even after the report on weekend evolution of the bacterial flagellum in Pseudomonas flourescens which fluoresces when exposed to UV light. It seems that neo-Darwinian theorists and other theorists are not interested in linking Darwin’s “conditions of life” from Schrodinger’s claims about sunlight to Dobzhansky’s claims about the light of evolution. Do the theorists intend to keep ignoring everything known to serious scientists about the energy-dependent links from angstroms to ecosystems?
See: Structural diversity of supercoiled DNA
Excerpt:
Our cryo-ET, biochemical, and computational studies show the astounding versatility and dynamism of DNA depending on the degree of supercoiling. DNA simultaneously exists in a largely inactive B-form with bases tucked in and protected and an active, highly varied structure with exposed bases. Our data provide relative comparisons of supercoiling-dependent twisted, writhed, curved, and kinked conformations and associated base exposure. Each of these structural features may be differentially recognized by the proteins, nucleic acids, and small molecules that modulate DNA metabolic processes.
My comment: The differential structure features of DNA are RNA-mediated. Energy-dependent amino acid substitutions link angstroms to ecosystems in all living genera, and virus-driven energy theft links mutations to all pathology.
See for examples: Nutrient-dependent/pheromone-controlled adaptive evolution: a model
My comment: For details on the conserved molecular mechanisms that link RNA-mediated amino acid substitutions to cell type differentiation in all cell types of all individuals of all species, see my invited review of nutritional epigenetics: Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems
Abstract excerpt:
This atoms to ecosystems model of ecological adaptations links nutrient-dependent epigenetic effects on base pairs and amino acid substitutions to pheromone-controlled changes in the microRNA / messenger RNA balance and chromosomal rearrangements. The nutrient-dependent pheromone-controlled changes are required for the thermodynamic regulation of intracellular signaling, which enables biophysically constrained nutrient-dependent protein folding; experience-dependent receptor-mediated behaviors, and organism-level thermoregulation in ever-changing ecological niches and social niches. Nutrient-dependent pheromone-controlled ecological, social, neurogenic and socio-cognitive niche construction are manifested in increasing organismal complexity in species from microbes to man.
See for comparison: This protein designer aims to revolutionize medicines and materials
Excerpt:
Baker’s team has all but solved one of the biggest challenges in modern science: figuring out how long strings of amino acids fold up into the 3D proteins that form the working machinery of life.
Conclusion: Protein designers have shed nature’s constraints and are now only limited by their imagination. “We can now build a whole new world of functional proteins,” Baker says.”
My comment: RNA-mediated protein folding chemistry is biophysically constrained by nutrient energy-dependent microRNA flanking sequences, which link the details in our section on molecular epigenetics from our 1996 Hormones and Behavior review to all morphological and behavior diversity in all living genera via RNA-mediated amino acid substitutions.
Baker fails to mention that quantized energy is the link to energy-dependent changes and all links from angstroms to ecosystems via RNA-mediated protein folding chemistry in all living genera. That fact requires the ‘design’ of an innate immune system that protects all organized genomes from virus-driven energy theft and genomic entropy so that organisms can reproduce when enough food is available. If not enough food or energy is available to support the physiology of reproduction, metabolic networks cannot be linked to genetic networks via RNA-mediated amino acid substitutions and protein folding. But virus-driven energy theft can clearly be linked from the Zika virus to differences in craniofacial morphology and brain development by smaller skull size in victims of the transgenerational epigenetic inheritance of the virus.
The facts about the Zika virus-damaged DNA link virus-driven pathology to every aspect of development during life history transitions that are altered by the energy theft. Plasticity associated with olfactory input in this example, and many others, can be examined in the context of what is currently known to serious scientists, or it can be placed back into the context of the pseudoscientific nonsense touted by neo-Darwinian theorists.
See: Olfactory organ of Octopus vulgaris: morphology, plasticity, turnover and sensory characterization
See also:
VIDEO
See also: Light ‘drives’ adaptation; nothing ‘drives’ evolution (2)
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0
Methylation and the innate immune system (2)
4 MIN READ
0
Science vs Secularism: Molecular Mechanisms or Math?
6 MIN READ
0
Methylation and the Innate Immune System
< 1 MIN READ
0
Sexual communication signals: New Insights!
10 MIN READ
0
Host-derived creation of all pathology (2 of 2)
9 MIN READ
0
Stem cells do not create themselves
3 MIN READ
0
Pseudoscientists hate what science explains! (3)
4 MIN READ
0
Your indifference is killing you and others
5 MIN READ
0
Your indifference is killing you and others (3)
4 MIN READ
0
Your indifference is killing you and others (4)
4 MIN READ
0
Automagical protein creation sans energy
9 MIN READ
0
The Origin of Information (4)
4 MIN READ
0
Evolutionary congruence (losers) vs ecological adaptation (winners)
3 MIN READ
0
Pattern recognition vs evolutionary processes (revisited)
7 MIN READ
0
Energy-dependent physical and biophysical constraints (10)
8 MIN READ
0
Energy-dependent physical and biophysical constraints (9)
3 MIN READ
0
Energy-dependent physical and biophysical constraints (6)
8 MIN READ
0
Energy-dependent physical and biophysical constraints (3)
2 MIN READ
0
Energy-dependent physical and biophysical constraints (1)
5 MIN READ
0
Cell type assembly and the space-time continuum
2 MIN READ
0
The emergence of light as energy from a life-giving star (2)
2 MIN READ
0
God’s shrinking role in salvation (3)
9 MIN READ
0
God's shrinking role in salvation (3)
9 MIN READ
0
Food energy-dependent cell type differentiation (2)
10 MIN READ
0
Hard Science vs the neo-Darwinian “magic box”
9 MIN READ
0
Infections and age change the odor of wine and people
4 MIN READ
0
From E. coli to monkeys and mankind: Theories vs models (4)
2 MIN READ
0
From E. coli to monkeys and mankind: Theories vs models (2)
6 MIN READ
0
From E. coli to monkeys and mankind: Theories vs models
7 MIN READ
0
Food energy-dependent epigenetic adaptation (3)
3 MIN READ
0
Food energy-dependent epigenetic adaptation (2)
< 1 MIN READ
0
Food energy-dependent epigenetic adaptation
11 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (5)
4 MIN READ
0
Cytosis in the light of evolution
5 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (4)
2 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability (3)
5 MIN READ
0
Energy-dependent epigenetic translation to mRNA stability
8 MIN READ
0
Energy as information and constrained endogenous RNA interference (4)
7 MIN READ
0
What energy source do proteins prefer?
6 MIN READ
0
Energy-dependent microRNA biogenesis
4 MIN READ
0
Draining the academic swamp of parasites
3 MIN READ
0
The death of CRISPR; long live endogenous RNAi
5 MIN READ
0
The Virus-Driven Suicide March for Science
5 MIN READ
0
Feng Zhang refutes theistic evolution
4 MIN READ
0
Open Science: Closed to facts about microRNAs
6 MIN READ
0
What is life without sunshine?
2 MIN READ
0
Viruses in pathogenic variants disrupt alternative splicings (2)
3 MIN READ
0
Viruses in pathogenic variants disrupt alternative splicings
2 MIN READ
0
Respiration-dependent endogenous RNA interference
4 MIN READ
0
Epigenetically-effected nucleosome repositioning sheds Dobzhansky’s light on evolution
3 MIN READ
0
Synthetic RNA-based switches
2 MIN READ
0
Sunlight bursts the social bubble of physics and math
3 MIN READ
0
Functionally interdependent editing and methylation
4 MIN READ
0
Cytosis: Biology Content
7 MIN READ
0
Light-activated feedback loops vs self-organization of ecosystems
7 MIN READ
0
Cytosis: A Cell Biology Board Game
< 1 MIN READ
0
Virulence and your UTI
2 MIN READ
0
Life in your UV light-constrained galaxy
5 MIN READ
0
Thinking about energy is not radical re-thinking
6 MIN READ
0
Food for thought: Penrose v Ellis (1)
5 MIN READ
0
Magnussen’s “Faith fools” keep the faith
3 MIN READ
0
Energy-dependent pheromone-controlled entropy (4)
3 MIN READ
0
Proof: Sunlight is energy as information
< 1 MIN READ
0
Energy-dependent pheromone-controlled entropy (2)
6 MIN READ
0
Sunlight: the essence of precision medicine and world peace
6 MIN READ
0
The essence of precision medicine: drug targets or healthy longevity?
4 MIN READ
0
The essence of precision medicine
4 MIN READ
0
Ab initio cell wall invention, emergence, and evolution (2)
8 MIN READ
0
RNA-mediated adult learning, memory, and neurogenesis
3 MIN READ
0
Energy-dependent allelic imbalances, viruses, and pathology
3 MIN READ
0
Ab initio cell wall invention, emergence, and evolution (1)
2 MIN READ
0
Biologically uninformed biologists fight back and lose
3 MIN READ
0
Theistic evolutionists fight back and lose (3)
4 MIN READ
0
Theistic evolutionists fight back and lose
4 MIN READ
0
Young earth creationists refute theistic evolution
3 MIN READ
0
Bill Gates refutes theistic evolution (prequel)
2 MIN READ
0
Bill Gates refutes theistic evolution (sequel)
8 MIN READ
0
Bill Gates refutes theistic evolution
4 MIN READ
0
Emily Witkin refutes theistic evolution
2 MIN READ
0
Wikipedia refutes theistic evolution
4 MIN READ
0
RNA editing refutes theistic evolution
4 MIN READ
0
Pseudoscientists fail to refute theistic evolution
4 MIN READ
0
Stuart Kauffman refutes theistic evolution
3 MIN READ
0
May the anti-entropic force of sunlight be with you
4 MIN READ
0
Francis S. Collins refutes theistic evolution
6 MIN READ
0
Energy is information. Objections over ruled. You’re fired!
7 MIN READ
0
Happy Darwin Day (2017)
4 MIN READ
0
George Church refutes theistic evolution (3)
5 MIN READ
0
George Church refutes theistic evolution (2)
2 MIN READ
0
George Church refutes theistic evolution
5 MIN READ
0
Physicists: Desperate Acts (revisited)
6 MIN READ
0
Energy as information and constrained endogenous RNA interference (3)
4 MIN READ
0
Virus-driven energy theft and premature death
3 MIN READ
0
Fighting for virus-driven pathology
5 MIN READ
0
Dobzhansky 1973 and precision medicine (5)
3 MIN READ
0
Atomic theory vs facts about hydrogen-atom transfer
4 MIN READ
0
Dobzhansky 1973 and Precision Medicine (2)
5 MIN READ
0
Dobzhansky 1973 and precision medicine
6 MIN READ
0
Twisted theories and weaponized facts
3 MIN READ
0
Autophagy: from pre-mRNAs to microRNAs, enhancers, QTLs et al.
6 MIN READ
0
Mutations: the “driving force” behind human brain complexity?
6 MIN READ
0
Mutations: the "driving force" behind human brain complexity?
6 MIN READ
0
Science journalists or paid propagandists? (2)
3 MIN READ
0
Critical values expose virus-driven energy theft (2)
4 MIN READ
0
Theorists sell hidden energy (2)
4 MIN READ
0
Critical values expose virus-driven energy theft
6 MIN READ
0
Theorists sell hidden energy
3 MIN READ
0
Evolved patterns of brain stimulation
3 MIN READ
0
Chirality is reality
6 MIN READ
0
Energy-dependent hydrogen bonds in supercoiled DNA
7 MIN READ
0
Energy-dependent chirality
6 MIN READ
0
Energy-dependent alternative splicings 1996 – 2016 (2)
5 MIN READ
0
Vietnam Veterans and others with glioblastoma
3 MIN READ
0
Energy-dependent sensory maps (1996-2016)
5 MIN READ
0
Energy-dependent alternative splicings 1996 – 2016
12 MIN READ
0
Energy-dependent oscillating gene networks organize life
4 MIN READ
0
2016 obfuscated facts about energy as information
5 MIN READ
0
More refutations of neo-Darwinian nonsense
7 MIN READ
0
Re-inventing mutation-driven evolution (2)
4 MIN READ
0
Sudden death indel polymorphism
4 MIN READ
0
Anti-entropic virucidal energy as information
10 MIN READ
0
Expunging the distinguished public
2 MIN READ
0
Autophagy is the antiphage defense strategy
3 MIN READ
0
Tasting light links energy from creation to adaptation
9 MIN READ
0
Combating evolution: Battlefield medicine vs politicized science
6 MIN READ
0
The futility of The Battlefield FB group
10 MIN READ
0
Metabolic Phenotyping Research
2 MIN READ
0
Phylogenetic similarity sans energy
2 MIN READ
0
Happy biophysically constrained Thanksgiving (in the USA)
3 MIN READ
0
De novo gene creation: Ignoring the experimental evidence
7 MIN READ
0
Energy-dependent coulombic, autophagic, polycombic healthy longevity
4 MIN READ
0
Light, behavior and autophagy, a gender-specific risk factor
4 MIN READ
0
Controlled amino acid treatment of all pathology
4 MIN READ
0
Energy-dependent purifying selection / autophagy (3)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (5)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (6)
3 MIN READ
0
Energy-dependent purifying selection / autophagy
2 MIN READ
0
Optogenetics: Let there be virucidal light!
2 MIN READ
0
Base pairs, amino acids and phenotypes
10 MIN READ
0
Survivors of RNA-mediated terrorism
5 MIN READ
0
Building delicious base pairs in class. It’s elementary Watson and Crick
3 MIN READ
0
Building delicious base pairs in class. It's elementary Watson and Crick
3 MIN READ
0
Epigenetically effected energy-dependent fluorescence
5 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (4)
< 1 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (2)
2 MIN READ
0
From Precis to Proof in 6000 years (3)
2 MIN READ
0
From Precis to Proof in 6000 years
9 MIN READ
0
Coulombic interactions facilitate polycombic adaptation
5 MIN READ
0
Top-down adaptation vs bottom-up evolution
6 MIN READ
0
Polycombic ecological adaptation as a science, not a theory (2)
12 MIN READ
0
Polycombic ecological adaptation as a science, not a theory
3 MIN READ
0
Attacking Young Earth Creationists
5 MIN READ
0
80 years of causal analysis (1936 – 2016)
11 MIN READ
0
Did evolution autophosphorylate your kinases? (3)
2 MIN READ
1
The natural success of RNAi and failed treatment
7 MIN READ
0
Hecatombic evolution via oncocers and oncohistones
9 MIN READ
0
Did evolution autophosphorylate your kinases? (2)
5 MIN READ
1
Nutrient-dependent autophagy
3 MIN READ
0
Life is energy-dependent task management
3 MIN READ
0
Hypothesis free pseudoscience vs facts (5)
6 MIN READ
0
Hypothesis free pseudoscience vs facts (2)
5 MIN READ
0
The last RNA-mediated theory killer
< 1 MIN READ
0
Base pairs, olfaction and RNA thermometers
4 MIN READ
0
Chromatin: The structure of DNA (3)
4 MIN READ
0
Chromatin: The structure of DNA
6 MIN READ
0
Consciousness is simply food rearranged
2 MIN READ
0
Hydrogen-atom energy in DNA base pairs
6 MIN READ
0
DNA repair via junk DNA (2)
5 MIN READ
0
The Aquatic Ape / Waterside Ape divergence
6 MIN READ
0
Light energy-dependent active motifs
6 MIN READ
0
Light energy-induced base pair changes (2)
4 MIN READ
0
Light energy-induced base pair changes (1)
6 MIN READ
0
Displays of ecological adaptation
2 MIN READ
0
Virus-driven energy theft causes cancer
2 MIN READ
0
Linking RNA structure to function
3 MIN READ
0
How did the innate immune system evolve?
4 MIN READ
0
Plant microRNAs slow virus-driven aging
3 MIN READ
0
Increased soil pH and nutrient availability
4 MIN READ
0
Lawless evolution: No physics
4 MIN READ
0
Conserved biophotonic emissions
7 MIN READ
2
Virus-driven energy theft: honeybee model
3 MIN READ
0
Antithetical conclusions (7)
3 MIN READ
0
Antithetical conclusions (6)
3 MIN READ
0
Antithetical conclusions (4)
3 MIN READ
0
Anthetical conclusions (2)
5 MIN READ
0
Anthetical conclusions
3 MIN READ
0
Non-random pheromone-controlled cell type differentiation
3 MIN READ
0
RNAi: From magic bullet to billion dollar baby
4 MIN READ
0
Co-evolution and co-speciation replace neo-Darwinian nonsense
4 MIN READ
0
Pseudoscientists ignore what serious scientists prove
6 MIN READ
0
GC-rich neo-Darwinian train wreck
5 MIN READ
0
From angstroms to ecosystems
7 MIN READ
0
Food supplement or licensed immunostimulant?
6 MIN READ
0
Virus-driven downsizing of the human brain (3)
4 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity (2)
19 MIN READ
0
The end of neo-Darwinism
5 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity
4 MIN READ
0
The Origin of Information (2)
6 MIN READ
0
Invisible dark matter
< 1 MIN READ
0
Funding the Human Genome Project-Write
2 MIN READ
0
RNA-mediated programming of E.coli
< 1 MIN READ
0
Virus-driven downsizing of the human brain (2)
< 1 MIN READ
0
RNA methylation (revisited)
< 1 MIN READ
0
Virus-driven downsizing of the human brain
2 MIN READ
0
Virus altered thermodynamic stability
< 1 MIN READ
0
MicroRNAs and sexual orientation
8 MIN READ
0
RNA methylation, learning, memory and behavior,
< 1 MIN READ
0
Innate immunity and multiplexing
7 MIN READ
0
Amino acids and virus penetration
3 MIN READ
0
Masters of deception about nature (2)
7 MIN READ
0
Masters of deception about nature
8 MIN READ
0
The Mind’s Eyes (revisited)
10 MIN READ
0
Cracking the Olfactory Code?
5 MIN READ
0
RNA methylation, behavior, and disease
6 MIN READ
0
Energy-dependent RNA methylation (10)
4 MIN READ
0
Energy-dependent RNA methylation (8)
4 MIN READ
0
Energy-dependent RNA methylation (7)
7 MIN READ
0
Energy-dependent RNA methylation (5)
3 MIN READ
0
Energy-dependent RNA methylation (3)
10 MIN READ
0
Energy-dependent RNA methylation (2)
5 MIN READ
0
Energy-dependent RNA methylation (1)
6 MIN READ
0
Secular humanism and ecoterrorism
4 MIN READ
0
Thermotolerance and longevity (2)
3 MIN READ
0
War Games: False Flag Terrorism
5 MIN READ
0
Energy-dependent biodiversity (2)
2 MIN READ
0
The tipping point? 50,000 publications (3)
6 MIN READ
0
Neo-Darwinism failed in 1995
3 MIN READ
0
Magic, Miracle, or Molecular Mechanism (3)
2 MIN READ
0
Countdown to Genetics and Genomics
< 1 MIN READ
0
Energy-dependent creation and entropy
4 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (4)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (3)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics
9 MIN READ
0
RNA splicing, genetic variation, and disease
2 MIN READ
0
Wasted Templeton Funding (3)
2 MIN READ
0
Wasted Templeton Funding (2)
2 MIN READ
0
Millions of water molecules vs years of evolution
2 MIN READ
0
A bumper crop of virus-infected weeds and people
2 MIN READ
0
Molecular Diagnostics: What is unprotected life (4)
2 MIN READ
0
Molecular Diagnostics: What is unprotected life (3)
5 MIN READ
0
Molecular Microbial Ecology
8 MIN READ
0
Molecular Diagnostics: What is unprotected life? (2)
7 MIN READ
0
Molecular Diagnostics: What is unprotected life?
2 MIN READ
0
Ricki Lewis’ Time Machine (4)
8 MIN READ
0
Creating and/or programming the immune system
< 1 MIN READ
0
Half truths support theories without facts
4 MIN READ
0
Ricki Lewis’ Time Machine (3)
5 MIN READ
0
Creating nutrient-dependent life with enough genes to survive
3 MIN READ
0
Confusing effects and affects of visual input
2 MIN READ
0
Selective reporting of inferences: examples of pseudoscience
14 MIN READ
0
Ignore the evidence: Rachel Feltman
5 MIN READ
0
Virus-driven disorder prevention and health promotion
6 MIN READ
0
Stress-linked population-level history dependence
5 MIN READ
0
Do not miss the misrepresentations
2 MIN READ
0
Energy dependent RNA-mediated immunity (3)
8 MIN READ
0
Energy dependent RNA-mediated immunity (2)
10 MIN READ
0
RNA-mediated DNA modifications
5 MIN READ
0
Science vs semantics
4 MIN READ
0
From angstroms to ecosystems and entropy
2 MIN READ
0
Bacteria see the light and they adapt (2)
5 MIN READ
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands
3 MIN READ
0
Effects on invertebrate GnRH and affects on primate behavior
6 MIN READ
0
Hybrids: making microbes and Democrats into monkey’s uncles?
11 MIN READ
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA (2)
9 MIN READ
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA
2 MIN READ
0
Hydrogen-atom transfer in DNA base pairs (7)
5 MIN READ
0
Will modern human populations adapt to the Zika virus?
5 MIN READ
0
Models of scientific literacy
3 MIN READ
0
Organic Compounds and the Miracle of Smell and Taste
7 MIN READ
0
Neuroscience Virtual Event vs AAAS Symposium
3 MIN READ
0
Cancer: Evolution 2.0’s Blind Spot
13 MIN READ
0
Ricki Lewis’ Time Machine (2)
6 MIN READ
0
Hydrogen-atom transfer in DNA base pairs (5)
10 MIN READ
0
Blood test links atoms to ecosystems
2 MIN READ
0
Stress-induced energy-dependent DNA repair
4 MIN READ
0
Teleophobes vs teleophiles: a recent history
2 MIN READ
0
Ecological genomics: teleophobes respond (too late)
10 MIN READ
0
Genes, orchid odors, and pheromones from blonds
5 MIN READ
0
Amino acid substitutions, stress, and human behavior
3 MIN READ
0
Finding peace and π in the light of H bond energy (2)
8 MIN READ
0
RNA methylation, RNA-directed DNA methylation, learning and memory
3 MIN READ
0
Finding peace and π in the light of H bond energy
5 MIN READ
0
Epigenetic (re)programming of behavior (3)
5 MIN READ
0
Assumptions prove ignorance (2)
5 MIN READ
0
Epigenetic (re)programming of behavior
4 MIN READ
0
Assumptions prove ignorance
5 MIN READ
0
Neo-Darwinian sink testing
2 MIN READ
0
NORAD: air defense and defense against genomic entropy
7 MIN READ
0
Life history transitions and RNA-mediated survial
2 MIN READ
0
Did Dobzhansky see the UV light of creation?
10 MIN READ
0
RNA-mediated theory killers (6) (7) (8) (9) (10)
5 MIN READ
0
Manufacturing fossil “evidence”
4 MIN READ
0
RNA-mediated theory killers (4)
9 MIN READ
0
RNA-mediated theory killers (5)
2 MIN READ
0
RNA-mediated theory killers (3)
7 MIN READ
0
Ecological adaptations you cannot live without
6 MIN READ
0
RNA-mediated regulatory mechanisms link microbes to humans (3)
5 MIN READ
0
RNA-mediated theory killers
6 MIN READ
0
Natural cooperation and Evolution 2.0
6 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (3)
8 MIN READ
0
Organization of biological sequences
2 MIN READ
0
Virally derived RNA molecules and cell types
2 MIN READ
0
Positive feedback loops and epigenetic traps
2 MIN READ
0
Stress-perturbed mitochondrial dysfunction (2)
5 MIN READ
0
Behavioral Immune System model
4 MIN READ
0
Stress-perturbed mitochondrial dysfunction
4 MIN READ
0
Sensationalizing no new mechanism
2 MIN READ
0
Too complex for the Complex Biological Systems Alliance
4 MIN READ
0
Receptor methylation controls behavior
2 MIN READ
0
Virus, transposon and plasmid evolution
< 1 MIN READ
0
Conserved molecular mechanisms
< 1 MIN READ
0
Models are not theories (2)
2 MIN READ
0
Models are not theories (1)
2 MIN READ
0
Can veterans and other prisoners escape pseudoscience?
2 MIN READ
0
Cyclic cosmology and the stability of organized genomes
4 MIN READ
0
Unraveling the secrets of RNA-mediated events
2 MIN READ
0
Ecological speciation. Get it, theorists?
< 1 MIN READ
0
Designing, engineering, and protecting biodiversity
3 MIN READ
0
The virome, microbiome, replisome and supercoiled DNA
2 MIN READ
0
Skip the politics; embrace the facts
5 MIN READ
0
Neo-Darwinian logic is nonsense
3 MIN READ
0
FREE* SAMPLE: Histone modification
4 MIN READ
0
Biophysically constrained or unconstrained?
2 MIN READ
0
Mutated mitochondrial genes vs Supercoiled DNA
2 MIN READ
0
Mystery machine vs medical intelligence
2 MIN READ
0
Molecule of life vs animal experiments
< 1 MIN READ
0
Keep the gay gene theory?
< 1 MIN READ
0
Supercoiled DNA constrains virus-driven genomic entropy
2 MIN READ
0
Anti-entropy: an evolutionist’s afterthought
11 MIN READ
0
Gene creation (revisited)
2 MIN READ
0
Somatic hypermutation vs RNA-mediated events
2 MIN READ
0
Protosuns, prebiotic molecules, proteins, and people
4 MIN READ
0
Hematopoiesis and practopoiesis
4 MIN READ
0
Easy editing: Reinventing our RNA world
3 MIN READ
0
Decreased phenotypic variation: Faith in Facts
7 MIN READ
1
Protein isoforms do not evolve
3 MIN READ
0
Viruses and ecologically adapted animals
2 MIN READ
0
Correctly modeling life on this planet
3 MIN READ
0
Correctly modeling ecological adaptation
4 MIN READ
0
Behavior (4): All responses are RNA-mediated in birds
4 MIN READ
0
Nutritional epigenetics, exercise, and immune system integrity
4 MIN READ
0
Quantum physics, quantum biology, and quantum consciousness
4 MIN READ
0
Physicists: Desperate Acts
16 MIN READ
0
ISHE's human ethology group
2 MIN READ
0
Understanding cell type differentiation
3 MIN READ
0
Unified nutritional and molecular mechanisms
9 MIN READ
0
RNA-mediated species specificity
2 MIN READ
0
ALPHA GENOMIX
7 MIN READ
2
RNA-mediated cell type differentiation and behavior
3 MIN READ
0
Metabolism, fixation, health or neurodegerative disorder
2 MIN READ
0
Nutrition, pheromones and cancer (2)
2 MIN READ
0
Darwinian theories vs Darwin's facts
2 MIN READ
0
Pheromones and cancer
4 MIN READ
0
A flawed model: no tripartate synapse in the adult brain
3 MIN READ
0
Epigenetic effects underlie sexual preferences IV
< 1 MIN READ
0
Pheromone-induced learning: a NEW model?
2 MIN READ
0
The challenges of a Darwinian approach to anything
3 MIN READ
0
Epigenetic effects of viruses on cellular homeostasis
< 1 MIN READ
0
[…] See: Light ‘drives’ adaptation; nothing ‘drives’ evolution […]