MicroRNAs biophysically constrain behavior (2)
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Excerpt:
Researchers, like Shunsuke Suzuki, who cannot link photonic coupling from quantum physics to biophysically constrained atomic energy via classical physics and quantum chemistry prevent scientific progress, They are limited to asking questions that have already been answered by serious scientists.
MicroRNA 1-20 of more than 70,400
The fact that the energy-dependent creation of microRNAs links RNA-mediated cell type-differentiation to biophysically constrained viral latency and all morphological phenotypes has been established.
See: PAN-cancer analysis of S-phase enriched lncRNAs identifies oncogenic drivers and biomarkers
…using nascent RNA capture sequencing, we identify 1145 temporally expressed S-phase-enriched lncRNAs. Among these, 570 lncRNAs show significant differential expression in at least one tumor type across TCGA data sets.
Reported as: RNA-based therapy cures lung cancer in mouse models
By turning down the activity of a specific RNA molecule researchers at Sahlgrenska Academy, Sweden, have cured lung tumors in mice by 40-50 percent. The results, published in Nature Communications, represent the tip of the iceberg in an extensive research project in which 633 new biomarkers for 14 types of cancer have been identified.
Ongoing support for my model of Energy as information and constrained endogenous RNA interference continues to link RNA-mediated differences in human populations to biophysically constrained viral latency and survival. Why haven’t others accepted the fact that there must be a link from the RNA-mediated differences to behavior? Morphological and behavioral phenotypes are energy-dependent and receptor-mediated.
See: Vital Signs: Racial Disparities in Age-Specific Mortality Among Blacks or African Americans — United States, 1999–2015
See also:
1) Vascular Endothelial Growth Factor Receptor 3 Controls Neural Stem Cell Activation in Mice and Humans (2015)
2) Delayed Dopamine Signaling of Energy Level Builds Appetitive Long-Term Memory in Drosophila (2015)
Reported as: Fruit flies remember a good meal, Blood growth factor activates neural stem cells
…the fruit fly brain is wired to remember and crave sweeter, energy-rich foods. After smelling and consuming a meal, such as a glob of sugar, information about the food’s energy content is relayed via dopaminergic neurons to a fruit fly’s olfactory long-term memory center.
The ability to remember a good meal is linked to a single amino acid substitution in one or more receptors.
3) A Single Amino Acid Substitution in the Activation Loop Defines the Decoy Characteristic of VEGFR-1/FLT-1 (2006)
The link from the food energy-dependent creation of microRNAs and the creation of enzymes to the single amino acid substitution that controls receptor-mediated neural step cell activation in mice and humans may not be obvious. For instance, the acronym VEGFR might not be linked to other reports on Vascular Endothelial Growth Factor Receptors.
The likelihood of establishing facts about top-down causation and biophysically constrained viral latency is reduced as each step towards neo-Darwinian pseudoscientific nonsense brings another level of obfuscation. See for example:
Identification of Multiple Forms of RNA Transcripts Associated with Human-Specific Retrotransposed Gene Copies (2016)
Duplicated genes are abundant in eukaryotic genomes and thus are presumed to play important roles in evolution.
Duplicated genes do not create themselves. The de novo creation of genes is energy-dependent and receptor-mediated. That fact establishes all the links from top-down causation to biophysically constrained viral latency and ecological adaptations via the creation of RNA and energy-dependent fixation of RNA-mediated amino acid substitutions.
If serious scientists understand the facts about food energy-dependent pheromone-controlled ecological adaptations in species from microbes to humans, questions like this are not likely to arise. VEGF165b elevation in pulmonary arterial hypertension patients, causative or adaptive? (4/1/18)
No reply is required. But see: VEGF165b elevation in pulmonary arterial hypertension patients, causative or adaptive? -Reply. (4/1/18)
Shunsuke Suzuki is a co-author of the reply. I am not interested in reading about questions or replies that are placed into the context of ridiculous theories, or attending meetings on Epigenetics & Chromatin where discussion of the emergence of novel CpG islands and genomic imprinting in mammalian evolution are discussed.
See for comparison: Direct Photonic Coupling of a Semiconductor Quantum Dot and a Trapped Ion (2015)
Understanding the key role played by single atoms and ions in the context of elementary quantum information processing protocols is required to answer questions about top-down causation and adaptation. Researchers, like Shunsuke Suzuki, who cannot link photonic coupling from quantum physics to biophysically constrained atomic energy via classical physics and quantum chemistry prevent scientific progress, They are limited to asking questions that have already been answered by serious scientists.
See Frohlich (1968) Long-range coherence and energy storage in biological systems
The supplied energy is thus not completely thermalized but stored in a highly ordered fashion.
See also: Schrödinger at 75 – The Future of Biology – September 5-6, 2018
The future of biology lies in the understanding of how the creation of the sun’s anti-entropic energy links RNA-mediated top-down causation via natural selection for energy-dependent codon optimality in the context of novel CpG islands and genomic imprinting. The RNA-mediated genomic imprinting must be linked to biophysically constrained viral latency. It is ridiculous to link the systems complexity of cell type differentiation and cancer prevention to mammalian evolution without consideration of how behavior could be linked to biophysically constrained cell type differentiation.
See for instance: CpG islands microRNA
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Allen Institute confirms food energy is information
6 MIN READ
0
RNA-mediated adult learning, memory, and neurogenesis
3 MIN READ
0
Energy-dependent allelic imbalances, viruses, and pathology
3 MIN READ
0
Theistic evolutionists fight back and lose (2)
4 MIN READ
0
Theistic evolutionists fight back and lose
4 MIN READ
0
Young earth creationists refute theistic evolution
3 MIN READ
0
Bill Gates refutes theistic evolution (prequel)
2 MIN READ
0
Bill Gates refutes theistic evolution (sequel)
8 MIN READ
0
Bill Gates refutes theistic evolution
4 MIN READ
0
RNA editing refutes theistic evolution
4 MIN READ
0
Pseudoscientists fail to refute theistic evolution
4 MIN READ
0
Energy is information. Objections over ruled. You’re fired!
7 MIN READ
0
George Church refutes theistic evolution (2)
2 MIN READ
0
Physicists: Desperate Acts (revisited)
6 MIN READ
0
Energy as information and constrained endogenous RNA interference (2)
2 MIN READ
0
Dobzhansky 1973 and precision medicine (5)
3 MIN READ
0
Dobzhansky 1973 and precision medicine (4)
5 MIN READ
0
Dobzhansky 1973 and Precision Medicine (2)
5 MIN READ
0
Trump’s appeal to common sense
2 MIN READ
0
Dobzhansky 1973 and precision medicine
6 MIN READ
0
Twisted theories and weaponized facts
3 MIN READ
0
Mutations: the “driving force” behind human brain complexity?
6 MIN READ
0
Mutations: the "driving force" behind human brain complexity?
6 MIN READ
0
Theorists sell hidden energy (2)
4 MIN READ
0
Chirality is reality
6 MIN READ
0
Energy-dependent chirality (2)
3 MIN READ
0
Energy-dependent oscillating gene networks organize life
4 MIN READ
0
2016 obfuscated facts about energy as information
5 MIN READ
0
Bio-functional information
3 MIN READ
0
Energy-dependent self-organization and self repair
8 MIN READ
0
Explorers who do not know what is known (2)
6 MIN READ
0
Autophagy is the antiphage defense strategy
3 MIN READ
0
Energy-dependent de novo creation and neurogenesis (2)
5 MIN READ
0
Energy-dependent de novo creation and neurogenesis
7 MIN READ
0
Theories vs facts about polycombic adaptation
3 MIN READ
0
Politicized science: The demise of RNA-mediated.com?
3 MIN READ
0
Combating evolution: Battlefield medicine vs politicized science
6 MIN READ
0
The futility of The Battlefield FB group
10 MIN READ
0
Phylogenetic similarity sans energy
2 MIN READ
0
Happy biophysically constrained Thanksgiving (in the USA)
3 MIN READ
0
Energy-dependent purifying selection / autophagy (4)
2 MIN READ
0
Energy-dependent purifying selection / autophagy (6)
3 MIN READ
0
Energy-dependent purifying selection / autophagy
2 MIN READ
0
Survivors of RNA-mediated terrorism
5 MIN READ
0
Energy-dependent maternal-to-zygotic transition
6 MIN READ
1
Virus-driven mutation or amino acid substitution
5 MIN READ
0
Epigenetically effected energy-dependent fluorescence
5 MIN READ
0
Epigenetics and autophagy vs mutations and evolution (3)
< 1 MIN READ
0
Polycombic ecological adaptation as a science, not a theory (2)
12 MIN READ
0
Did evolution autophosphorylate your kinases? (3)
2 MIN READ
1
Did evolution autophosphorylate your kinases? (2)
5 MIN READ
1
Nutrient-dependent autophagy
3 MIN READ
0
Life is energy-dependent task management
3 MIN READ
0
Hypothesis free pseudoscience vs facts (4)
5 MIN READ
0
Hypothesis free pseudoscience vs facts (3)
3 MIN READ
0
The last RNA-mediated theory killer
< 1 MIN READ
0
Chromatin: The structure of DNA (3)
4 MIN READ
0
Chromatin: The structure of DNA
6 MIN READ
0
Consciousness is simply food rearranged
2 MIN READ
0
Hydrogen-atom energy in DNA base pairs
6 MIN READ
0
Light energy-dependent active motifs
6 MIN READ
0
Light energy-induced base pair changes (2)
4 MIN READ
0
Light energy-induced base pair changes (1)
6 MIN READ
0
The Aquatic Ape: New evidence?
4 MIN READ
0
Increased soil pH and nutrient availability
4 MIN READ
0
Conserved biophotonic emissions
7 MIN READ
2
Virus-driven energy theft: honeybee model
3 MIN READ
0
Antithetical conclusions (7)
3 MIN READ
0
GC-rich neo-Darwinian train wreck
5 MIN READ
0
The Origin of Information (2)
6 MIN READ
0
The tipping point? 50,000 publications (5)
3 MIN READ
0
Did “Nature” kill Steve Jobs? (3)
10 MIN READ
0
Invisible dark matter
< 1 MIN READ
0
Did “Nature” kill Steve Jobs?
3 MIN READ
0
Virus-driven downsizing of the human brain
2 MIN READ
0
Innate immunity and multiplexing
7 MIN READ
0
Masters of deception about nature (2)
7 MIN READ
0
The Mind’s Eyes (revisited)
10 MIN READ
0
Energy-dependent RNA methylation (7)
7 MIN READ
0
Energy-dependent RNA methylation (4)
5 MIN READ
0
Energy-dependent creation and entropy
4 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (4)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (3)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (2)
7 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics
9 MIN READ
0
MicroRNAs and/or QTLs: Who buried what?
2 MIN READ
0
Wasted Templeton Funding (2)
2 MIN READ
0
A bumper crop of virus-infected weeds and people
2 MIN READ
0
Molecular Diagnostics: What is unprotected life? (5)
5 MIN READ
0
Molecular Diagnostics: What is unprotected life (4)
2 MIN READ
0
Genome-gate: Follow the money?
4 MIN READ
0
Creating nutrient-dependent life with enough genes to survive
3 MIN READ
0
Confusing effects and affects of visual input
2 MIN READ
0
Selective reporting of inferences: examples of pseudoscience
14 MIN READ
0
Ignore the evidence: Rachel Feltman
5 MIN READ
0
Energy-dependent purpose vs teleophobic telorexia
12 MIN READ
0
Stress-linked population-level history dependence
5 MIN READ
0
Do not miss the misrepresentations
2 MIN READ
0
Energy dependent RNA-mediated immunity (5)
4 MIN READ
0
Energy dependent RNA-mediated immunity (4)
6 MIN READ
0
Energy dependent RNA-mediated immunity (2)
10 MIN READ
0
Energy-dependent RNA-mediated immunity (1)
10 MIN READ
0
Science vs semantics
4 MIN READ
0
Bacteria see the light and they adapt (2)
5 MIN READ
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands
3 MIN READ
0
Effects on invertebrate GnRH and affects on primate behavior
6 MIN READ
0
Hybrids: making microbes and Democrats into monkey’s uncles?
11 MIN READ
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA
2 MIN READ
0
Hydrogen-atom transfer in DNA base pairs (7)
5 MIN READ
0
Bacteria see the light and they adapt
7 MIN READ
0
Will modern human populations adapt to the Zika virus?
5 MIN READ
0
Cancer: Evolution 2.0’s Blind Spot
13 MIN READ
0
Ricki Lewis’ Time Machine (2)
6 MIN READ
0
Ricki Lewis’ Time Machine
5 MIN READ
0
Hydrogen-atom transfer in DNA base pairs (5)
10 MIN READ
0
The unoffically uninvited
3 MIN READ
0
Blood test links atoms to ecosystems
2 MIN READ
0
Ecological law, cooperation, and DNA repair
4 MIN READ
0
Amino acid substitutions, stress, and human behavior
3 MIN READ
0
RNA methylation, RNA-directed DNA methylation, learning and memory
3 MIN READ
0
Finding peace and π in the light of H bond energy
5 MIN READ
0
Epigenetic (re)programming of behavior
4 MIN READ
0
Life history transitions and RNA-mediated survial
2 MIN READ
0
Did Dobzhansky see the UV light of creation?
10 MIN READ
0
Researchers rename, reshuffle, and reveal their ignorance
3 MIN READ
0
Hydrogen-Atom Transfer in DNA Base Pairs (3)
3 MIN READ
0
Manufacturing fossil “evidence”
4 MIN READ
0
RNA-mediated theory killers (4)
9 MIN READ
0
RNA-mediated theory killers (2)
8 MIN READ
0
Natural cooperation and Evolution 2.0
6 MIN READ
0
A million dollar paradox?
2 MIN READ
0
MicroRNAs vs Red Queen hypothesis
4 MIN READ
0
Hydrogen-Atom Transfer in DNA Base Pairs
9 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair
2 MIN READ
0
Life and death predicted by DNA methylation
3 MIN READ
0
Nutrient-dependent trophic analogs
3 MIN READ
0
Positive feedback loops and epigenetic traps
2 MIN READ
0
Behavioral Immune System model
4 MIN READ
0
Let there be anti-entropic light (3)
6 MIN READ
0
Theorists can’t understand biology
6 MIN READ
0
Neuroplasticity
4 MIN READ
0
Receptor methylation controls behavior
2 MIN READ
0
Models are not theories (2)
2 MIN READ
0
Fossils vs cell types and the brain
3 MIN READ
0
Unraveling the secrets of RNA-mediated events
2 MIN READ
0
RNA central and RNA-mediated.com
6 MIN READ
0
Designing, engineering, and protecting biodiversity
3 MIN READ
0
The virome, microbiome, replisome and supercoiled DNA
2 MIN READ
0
Skip the politics; embrace the facts
5 MIN READ
0
700 million years of evolution?
5 MIN READ
0
Biophysically constrained or unconstrained?
2 MIN READ
0
Mutated mitochondrial genes vs Supercoiled DNA
2 MIN READ
0
RNA-mediated retrotransposon-mediated biodiversity
3 MIN READ
0
Mystery machine vs model (2)
2 MIN READ
0
Preventing genomic entropy
4 MIN READ
0
Energy and evolution: another opinion?
2 MIN READ
0
Supercoiled DNA constrains virus-driven genomic entropy
2 MIN READ
0
Let there be anti-entropic light (2)
4 MIN READ
0
Foundamentals of theory
4 MIN READ
0
Non-mainstream scientist shares Nobel prize in Medicine
3 MIN READ
0
Is mainstream science in “Science” pseudoscience?
5 MIN READ
0
Mechanisms of stress: from genes to cancer
9 MIN READ
0
Viruses come alive: Tree of life pseudoscience
6 MIN READ
0
Theorists have not seen the light (2)
3 MIN READ
0
Hijacked light energy and vertebrate pathology
4 MIN READ
0
Theorists have not seen the light
4 MIN READ
0
A 5-10K comparison of design principles to evolution
3 MIN READ
0
Alternative pre-mRNA splicing and ecological adaptation
7 MIN READ
0
Pathology: Eating and breathing viruses
2 MIN READ
0
Exosomes and the RNA-mediated future of medicine
5 MIN READ
0
Somatic hypermutation vs RNA-mediated events
2 MIN READ
0
Phytochemical link from the sun to cell types
2 MIN READ
0
Natural selection: an anti-entropic force?
2 MIN READ
0
Genome sequencing, cadherins, and quantum consciousness
6 MIN READ
0
“New” quantum biology. Pirating the old
3 MIN READ
0
Cell types, SNVs, CNVs, and chromosomes
3 MIN READ
0
Thermotolerance and Longevity
57 MIN READ
0
Is life the balance between quantum and classical physics?
3 MIN READ
0
Anti-entropic containment of energy: symbiosis 1.0
5 MIN READ
0
The “great filter” is an epigenetic trap
4 MIN READ
0
Information and communication (2)
6 MIN READ
0
Information and communication
2 MIN READ
0
From “Blood Music” to Evolution 2.0
5 MIN READ
0
Olfaction & the octopus and human genomes
3 MIN READ
0
Thermodynamic constraints did not evolve
3 MIN READ
0
Mammalian-wide interspersed repeats (MIRs)
2 MIN READ
0
Ecological speciation vs revised evolutionary syntheses
6 MIN READ
0
Ecology replaces the extended evolutionary synthesis
4 MIN READ
0
The stability of organized genomes (4)
3 MIN READ
0
The stability of organized genomes (3)
3 MIN READ
0
Epimutation.com: a domain of confusion
8 MIN READ
0
Light -induced nucleic acid-mediated gene duplication?
< 1 MIN READ
0
Viruses, amino acids, and somatic cell types (3)
9 MIN READ
0
Viruses, amino acids, and somatic cell types (2)
5 MIN READ
0
RNA-mediated terms of virus-induced en-deer-ment
2 MIN READ
0
Domestication via a single amino acid substitution
2 MIN READ
0
Becoming biologically informed (3)
3 MIN READ
0
Easy editing: Reinventing our RNA world
3 MIN READ
0
Is photic-zone ribosomal diversity linked to all biodiversity?
2 MIN READ
0
Picornaviruses moving between primates (or not)
2 MIN READ
0
Riding the wrong direction
3 MIN READ
0
Faithfully repaired DNA
5 MIN READ
0
RNA-mediated gene duplication, fixation, and ecological adaptation
6 MIN READ
0
MicroRNA controlled growth and brain development
7 MIN READ
0
MicroRNA – controlled ecological adaptations
5 MIN READ
0
Becoming biologically informed
2 MIN READ
0
Celebrating independence from ridiculous theories
3 MIN READ
0
“New” epigenetic mechanism for lifelong learning?
3 MIN READ
0
The sum of our RNA-mediated parts
2 MIN READ
0
Protein folding and Google page rank
2 MIN READ
0
Iron, ferritin, thyroxine
2 MIN READ
0
Virus-driven death by evolutionary theory
3 MIN READ
0
“Evolution” of sex differences?
2 MIN READ
0
Nutrient stress-induced RNA-mediated pathology
< 1 MIN READ
0
Amino acid substitutions are not mutations
2 MIN READ
0
What I cannot create I eliminate from discussion
3 MIN READ
0
RNA-mediated development
2 MIN READ
0
Healthy mutants
2 MIN READ
0
Uniquely epigenomic gene regulation
2 MIN READ
0
Alternative splicings: epigenetics meets pharmacogenomics
4 MIN READ
0
Epigenetic regulation of aging by glycine and GnRH
5 MIN READ
0
Physicians who practice evolutionary medicine?
3 MIN READ
0
Pattern recognition: biogeochemical structure and function
5 MIN READ
0
Viruses and the human-like microbiome
3 MIN READ
0
Informing the biologically uninformed
< 1 MIN READ
0
I forgot. How do mutations cause evolution?
4 MIN READ
0
One amino acid substitution, genes, and brain activity
3 MIN READ
0
Batch effect vs epigenetic effects
3 MIN READ
0
Gene expression, immortality, and cancer
6 MIN READ
0
Scientists lose. A sci-fi author gains credibility
2 MIN READ
0
Vitamin B3 and DNA repair
4 MIN READ
0
Ignoring systems complexity (it’s too complicated)
3 MIN READ
0
Five years of Ferguson
2 MIN READ
0
Virus-driven cancer treatment and prevention
2 MIN READ
0
The microbiome, pharmacogenetics, and privacy
< 1 MIN READ
0
A special issue on nutritional epigenetics
5 MIN READ
0
Retinoic acid + one receptor regulate the genome
3 MIN READ
0
Epigenetics: microRNAs effect an integrative pathway
4 MIN READ
0
Protein isoforms do not evolve
3 MIN READ
0
Tissue type variation and expression of genes
< 1 MIN READ
0
From gut bacteria to breast milk and back
5 MIN READ
0
Chance mutations — not natural selection
5 MIN READ
0
How to find a “holy grail” under your nose
3 MIN READ
0
Physics, chemistry, light, and life
2 MIN READ
0
MicroRNAs and the exposome
5 MIN READ
0
An epigenetic mark links algae, worms, and flies
2 MIN READ
0
Effect and affect of a single base-pair change
4 MIN READ
0
Thermodynamics and protein folding landscapes
2 MIN READ
0
Feedback loops link insects to human brains
2 MIN READ
0
Viruses and cell type differentiation
3 MIN READ
0
RNA-mediated cell types and precision medicine
5 MIN READ
0
DNA Methylation and organized genomes
7 MIN READ
0
Misunderstanding cancer
7 MIN READ
0
Nutrient-dependent RNA interference (2)
4 MIN READ
0
Mutisensory integration: watching the paradigm shift
12 MIN READ
0
Origin of life and cancer (1,2,3)
2 MIN READ
0
Silencing genes and serious scientists
3 MIN READ
0
The miRNA/mRNA balance: a suboptimal strategy?
2 MIN READ
0
Nutrient-dependent microRNAs control cell types
6 MIN READ
0
Too many targets for theories
3 MIN READ
0
Creating nothing but a theory (3)
4 MIN READ
3
Creating nothing but a theory (2)
4 MIN READ
0
Creating nothing but a theory
4 MIN READ
0
The quantum / classical RNA-mediated ‘tipping point’
3 MIN READ
0
Epigenetic switch links MicroRNAs to RNA-protein interactions
4 MIN READ
0
Quantum correlations/pseudoscience
3 MIN READ
0
Anti-entropic solar energy
5 MIN READ
0
Questions about life’s diversity
21 MIN READ
0
Luis P. Villarreal tells it like it is
3 MIN READ
0
Is DNA-directed transcription RNA-mediated?
2 MIN READ
0
What about birds?
5 MIN READ
0
RNA directed DNA methylation and cell types
4 MIN READ
0
Implicating microRNAs in cancer
2 MIN READ
0
From 3-D to epigenetically-effected 4-D genome make-up
5 MIN READ
0
Imagining that data historically supports evolutionary theory
7 MIN READ
0
How fast can evolutionary theory be changed?
5 MIN READ
0
Quantum Superpositions: let there be light
4 MIN READ
0
Constrained evolution is ecological adaptation
5 MIN READ
0
Models by evolutionary biologists are not models
2 MIN READ
0
The future of physics predicts no future for evolutionary theory
3 MIN READ
0
Glycine and GnRH: Am I being pedantic?
4 MIN READ
0
Eliminating correlations from evolutionary ecology
6 MIN READ
0
Evolutionary theorists justify fear of the Ebola viruses
2 MIN READ
0
RNA-mediated genetic engineering (Part 3)
< 1 MIN READ
0
Physics, Chemistry, and Molecular biology (PCMb)
2 MIN READ
0
RNA-directed DNA methylation and RNA-mediated events
5 MIN READ
1
Seemingly futile cycles are not thermodynamically futile
3 MIN READ
0
Insect homology and diversity attributed to mutations
2 MIN READ
0
Comparing divergent model organisms
2 MIN READ
1
Cell-type differentiation
2 MIN READ
0
