How to explain exercise-induced phenotype from molecular data: rethink and reconstruction based on AMPK and mTOR signaling

Excerpt: “…cellular and molecular phenotype for exercise capacity is always acquired from regular exercise or muscle contraction; it is absurd to use drug and gene modification…”

My comment: What is known about RNA-mediated events shows that the slightest deficit in nutrient uptake will be manifested in your exercise-induced physique, which is also epigenetically-effected by the pheromones of others via the same pathway.

Meanwhile, even some serious scientists claim that our morphological and behavioral phenotypes ‘evolved’ via mutations and natural selection, because they have no understanding of epigenetically-effected RNA-mediated events and how amino acid substitutions differentiate all cell types in all individuals of all species by stabilizing the DNA in organized genomes of species from microbes to man.

Amir Siddiqui  (Symmetry Gym) is the only trainer/owner I know who understands enough about molecular biology to include what is known in his approach to helping others develop their potential.

If others are also beginning to understand the difference between those who think supplements will help ensure their success and biological facts that explain morphological and behavioral phenotypes, their comments are welcome here.

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