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Welcome to RNA-Mediated

A Message From J.V.Kohl:

Here you will find information that links physics, chemistry, and molecular epigenetics via RNA-mediated events such as the de novo creation of olfactory receptor genes in order to encourage a public discussion of a paradigm shift.

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Can epigenetic inheritance occur without concurrent changes in morphology AND behavior?

Heritable Histones Scientists show how roundworm daughter cells remember the histone modification patterns of their parents. By Ruth Williams | September 18, 2014 My comment: Strike three, your theories are out. Re: Strike 1) Combating Evolution to Fight Disease Strike 2) RNA and dynamic nuclear organization Strike 3) Starvation-Induced Transgenerational Inheritance of Small RNAs in C. elegans Does anyone think this latest addition of experimental evidence on heritable histones is not just another thinly-veiled attempt to continue the fight against disease?…

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Memory of repression and memory of behavior (2)

“Mutations that become so common that they affect more than 1% of a population are called polymorphisms (for example, the human blood types A, B, AB, and O).“ The claim that human blood types are mutations should be supported with experimental evidence of biologically-based cause and effect. Ask your professor, “What evolutionary event linked the mutation to natural selection and the evolution of human blood types? How did nutrient-dependent cell type differentiation become mutation-initiated cell type differentiation, when it is…

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Memory of repression and memory of behavior

H3K27me and PRC2 transmit a memory of repression across generations and during development Reported as: How epigenetic memory is passed through generations: Sperm and eggs transmit memory of gene repression to embryos Date: September 18, 2014 Excerpt: “There are dozens of potential epigenetic markers. In studies that document parent-to-child epigenetic inheritance, it’s not clear what’s being passed on, and understanding it molecularly is very complicated. We have a specific example of epigenetic memory that is passed on, and we can…

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Quantum physics meets Evolutionary Psychology News

Capturing the motion of a single molecule in real time as it oscillates from one quantum state to another September 18, 2014 Excerpt: “It also moves researchers a step closer to viewing the molecular world in action — being able to see the making and breaking of bonds, which control biological processes such as enzymatic reactions and cellular dynamics.” My comment: The making and breaking of bonds controls all biological processes. Luca Turin tried to do move researchers a step closer…

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Nutrient-dependent pheromone-controlled exercise-induced physiques

How to explain exercise-induced phenotype from molecular data: rethink and reconstruction based on AMPK and mTOR signaling Excerpt: “…cellular and molecular phenotype for exercise capacity is always acquired from regular exercise or muscle contraction; it is absurd to use drug and gene modification…” My comment: What is known about RNA-mediated events shows that the slightest deficit in nutrient uptake will be manifested in your exercise-induced physique, which is also epigenetically-effected by the pheromones of others via the same pathway. Meanwhile,…

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Watching and waiting for more retractions

Brain Genetics Paper Retracted A study that identified genes linked to communication between different areas of the brain has been retracted by its authors because of statistical flaws. By Anna Azvolinsky | September 4, 2014 Excerpt: “This retraction raises the issue of how many papers may have falsely reported gene associations because of the constantly evolving changes in gene assemblies and boundaries. That’s really alarming to me.” My comment: I am alarmed by those who report anything in terms of…

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RNA-mediated ecological adaptations of teeth

Counting fish teeth reveals DNA changes behind rapid evolution By Robert Sanders, Media Relations | September 17, 2014 Excerpt: “This is one of the first cases where we find that the rules found for traits lost apply as well to traits gained,” said Miller. My comment: Traits are gained and lost in the context of nutrient-dependent, odor-induced, receptor-mediated, RNA-mediated events that lead to amino acid substitutions that differentiate cell types. The cell type differentiation must be manifested in morphological and…

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A molecular visualizer of worthwhile molecular biology

Ruben Gonzalez Jr.: Molecular Visualizer Associate Professor and Director of Graduate Studies, Department of Chemistry, Columbia University. Age 42 By Jef Akst | September 1, 2014 Excerpt: “Much of his group’s current work involves extending discoveries about translation in E. coli to the process in eukaryotes, with an eye toward human health and disease.” My comment: That sums up the frustration that other serious scientists must share when they hear pseudoscientific nonsense touted about mutations, natural selection, and the evolution…

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RNA-mediated species diversification from microbes to primates

Mycobacteriophage-drived diversification of Mycobacterium abscessus Biology Direct (15 September 2014) OPEN ACCESS Excerpt (with my emphasis): “Widespread occurrence of phage sequences in almost all studied M. abscessus complex isolates suggests that the rate of prophage invasion is faster than the rate of mutation, implying rapid evolution of M. abscessus.” My comment: The faster rate of prophase invasion suggests ecological adaptations occur more rapidly than evolution. That may be why no experimental evidence of biologically-based cause and effect suggests that evolution…

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RNA-mediated events found everywhere

Transcriptome-wide Mapping Reveals Widespread Dynamic-Regulated Pseudouridylation of ncRNA and mRNA Related articles Related blog posts on this site Reported as Scientists discover RNA modifications in some unexpected places Excerpt 1): “…there are multiple types of RNA, three of which—messenger RNA (mRNA), transfer RNA (tRNA), and ribosomal RNA (rRNA)—are essential for proper protein production. Moreover, RNAs that are synthesized during the process known as transcription often undergo subsequent changes, which are referred to as “post-transcriptional modifications.” My comment: These microRNA/messenger RNA-mediated…

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  • Randomness and Divine Providence
    A Q&A on randomness and God’s providence …the main goal is to really put together a collection of scholarly studies of these issues: physicists, biologists, […]
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