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Welcome to RNA-Mediated

A Message From J.V.Kohl:

Here you will find information that links physics, chemistry, and molecular epigenetics via RNA-mediated events such as the de novo creation of olfactory receptor genes in order to encourage a public discussion of a paradigm shift.

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Defeating disease and Communism (4)

March 16, 2021
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
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On 3/16/21, Timothy Normand Miller, in his role as the stupid atheist, @theosib2 wrote: If there were any of the typical indications of a designer in DNA, then I would consider that there must have been a designer. However, none of those can be found. Peptide synthesis at the origin of life 11/13/20 and The Amino Acid Composition of Quadruplex Binding Proteins Reveals a Shared Motif and Predicts New Potential Quadruplex Interactors 9/13/18 were linked to Properties and biological impact…

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Defeating disease and Communism (3)

March 12, 2021
James Kohl
Adaptations, Alternative Splicings, base editing, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Physics, RNA Directed, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity
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More than 117,000 published works that mention ‘microRNA‘ can be linked from: Playing games with quantum interference 3/10/21 via MicroRNAs organize intrinsic variation into stem cell states 3/5/20 and MicroRNA Involvement in Signaling Pathways During Viral Infection 3/10/20 to the game for ages 14+ Genotype. Everything known to intelligent serious scientists has been linked to Thomas Hunt Morgan’s claims about chromosomal rearrangements and sympatric speciation in flies and other insects. See also: Hypoxia associated multi-omics molecular landscape of tumor tissue…

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Defeating Disease and Communism (2)

March 12, 2021
James Kohl
Adaptations, biophotonics, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Physics, RNA interference, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity
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On 4/23/20 former President Donald J. Trump reportedly linked God’s Creation of sunlight and humidity to the energy-dependent weakening of coronaviruses via RNA–RNA interaction between host and virus, but see Experts say there’s no medical basis for Trump’s suggestion that sunlight, disinfectants may treat coronavirus 4/24/20 Jonathan Reiner, professor of medicine at The George Washington University Hospital, said there’s no medical basis for Trump’s statements about sunlight. Reiner’s stupid claim can be placed into the context of “…a computational model…

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Defeating Disease and Communism (1)

March 12, 2021
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Model Organisms, Physics, RNA Directed, RNA interference, RNA–Mediated Epigenetic Heredity, Subatomic, What's in the News
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Defeating Diseases with Energy 1/9/18 The mitochondria turn food’s hydrogen and carbon and inhaled oxygen into carbon dioxide (CO2), water and adenosine triphosphate, or ATP, which stores energy. God’s ATP-dependent Creation of RNA links protonated RNA interference to healthy longevity. See: Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation” (1964) The synthesis of RNA in isolated thymus nuclei is ATP dependent. For the link to RNA-mediated ecological adaptations, see:…

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Pheromones protect us from viruses (2)

March 5, 2021
James Kohl
Adaptations, biophotonics, Diseases & Disorders, Ecology, Light Energy, microRNA editing, RNA interference
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Recent advances in the regulation of plant miRNA biogenesis 3/5/21 MicroRNAs (miRNAs) are essential non-coding riboregulators of gene expression in plants and animals… plants use multiple mechanisms to control miRNA accumulation. All of the mechanisms are light-activated and they biophysically constrain viral latency across kingdoms via the physiology of reproduction. See: A Quick HYL1-Dependent Reactivation of MicroRNA Production Is Required for a Proper Developmental Response after Extended Periods of Light Deprivation  7/18/18 …plants alter microRNA (miRNA) biogenesis in response to…

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Pheromones protect us from viruses (1)

March 4, 2021
James Kohl
Adaptations, base editing, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, Physics, RNA Directed, RNA interference, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity
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Involvement of transposable elements in neurogenesis 3/24/20 appeared in my search for indexed articles that mention microRNA on 3/4/21. There are more than 116,500 others. See: microRNA  MicroRNAs, many of which arise from transposon transcripts, also play an important role in regulating the differentiation of neuronal stem cells. That fact was established in the mid-1990s and was linked From Fertilization to Adult Sexual Behavior (1996) via pre-mRNA-mediated stem cell differentiation across kingdoms in our section on molecular epigenetics. At that time…

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Impeach God or impeach Joe? (1)

March 3, 2021
James Kohl
Adaptations, Diseases & Disorders, Ecology, Light Energy, Model Organisms
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God’s Creation of energy as information has been linked to biophysically constrained viral latency by all intelligent serious scientists and most intelligent people. Neo-Darwinian theorists, Democrats, liberals, conspiracy theorists, Communists, and other atheists are exceptions. Are they intelligent people? See: Conductance selectivity of Na+ across the K+ channel via Na+ trapped in a tortuous trajectory, which was reported on 3/1/21 as New study challenges ‘established’ mechanism about selectivity of cellular ion channels For a historical perspective on what’s new, see:…

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Impeaching the God of Abraham (9)

March 1, 2021
James Kohl
Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Model Organisms, Physics, RNA Directed, RNA interference, RNA–Mediated Epigenetic Heredity
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In “Impeaching the God of Abraham (7) I linked achiral glycine in position 6 of the GnRH decapeptide from peptide synthesis at the origin of life to the patent for naturally occurring light-activated carbon fixation and protonated RNA interference. See also: Regulatory Mechanisms of Vitellogenesis in Insects 1/28/21 …microRNA (miRNA) and nutritional (amino acid/Target of Rapamycin and insulin) pathways interplay with JH and 20E signaling cascades to control insect vitellogenesis. This article is part of the Research Topic Germ Cell…

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Impeaching the God of Abraham (8)

February 28, 2021
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, microRNA editing, Model Organisms, Physics, RNA Directed, RNA editing, RNA interference, Variations
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2/22/21 In Case You Missed it. The cure for HIV and all other virus-driven pathology was announced today via an indexed publication found through my daily PubMed search for microRNA. Efficacy, accumulation, and transcriptional profile of anti-HIV shRNAs expressed from human U6, 7SK, and H1 promoters 12/31/20 & indexed on 2/22/21 announced “…a functional cure for HIV.” “The RNA polymerase III promoters H1, 7SK, and U6…” were linked to the cure or the effective treatment of all virus-driven diseases via…

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Impeaching the God of Abraham (10)

February 26, 2021
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, Physics, RNA Directed, RNA interference, RNA–Mediated Epigenetic Heredity
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sunlight and humidity can weaken the coronavirus — Donald J. Trump 4/23/20 …there’s no medical basis for Trump’s statements about sunlight.  Jonathan Reiner, professor of medicine at The George Washington University Hospital 4/24/20 Former president Trump was absolutely correct. He linked physics and chemistry to molecular biology and healthy longevity via Haplotype-resolved diverse human genomes and integrated analysis of structural variation 2/25/21 Structural variants (SVs) —inversions, deletions, duplications, and insertions ≥50 bp in length—and their breakpoints “…are generally more depleted…

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