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Welcome to RNA-Mediated

A Message From J.V.Kohl:

Here you will find information that links physics, chemistry, and molecular epigenetics via RNA-mediated events such as the de novo creation of olfactory receptor genes in order to encourage a public discussion of a paradigm shift.

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UV light, H2O, and epigenetic effects… (4)

November 5, 2020
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, RNA Directed
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Before submitting your scientific manuscript for peer review, ensure that your results are reproducible by rigorously validating reagents such as antibodies. 9/29/2020 Find out how: Knockout validation: Overcoming the perils of poor antibody specificity Also, remember to link God’s Creation of UV light and water from oxidative phosphorylation and helioribogenetics to biophysically constrained viral latency across kingdoms via the physiology of pheromone-regulated genetic processes, or you will be referred to as a “theorist.” The theorists are stuck with a failed…

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Election day blues for fools who “voted blue” (3)

November 4, 2020
James Kohl
Adaptations, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, microRNA editing, Model Organisms, Neuronal Plasticity, Physics, RNA interference, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity, Subatomic
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See first: Election day blues for fools who “voted blue” (2) Medical experts rip Trump’s suggestion that sunlight, disinfectants may treat coronavirus President Donald J. Trump linked God’s Creation of subatomic particles from differences in the energy of positively charged protons and negatively charged electrons to biophysically constrained healthy longevity across kingdoms via the physiology of reproduction. If Biden wins, we are a nation of losers like Jonathan Reiner. Play Biden’s stupid game, wear masks, and practice social distancing, or…

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Election day blues for fools who “voted blue” (2)

November 3, 2020
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Physics, RNA interference
One Comment

See first: Election day blues for fools who “voted blue” (1) Perhaps the biggest problem for Democrats, liberals, Communists and other atheists is that they cannot see the UV light and do not believe it is God’s example of what is there. Hydrogen ions are there. Start with that fact to link them from God’s Creation of energy to the potential of hydrogen (pH) and link changes in pH to peptide-dependent life via the physiology of reproduction and protonated RNA…

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Election day blues for fools who “voted blue” (1)

November 3, 2020
James Kohl
Adaptations, base editing, biophotonics, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Physics, RNA Directed, RNA interference, RNA–Mediated Epigenetic Heredity
One Comment

See first: microRNA-mediated quantum error correction (4) See also: Biofluorescence in the platypus (Ornithorhynchus anatinus) 10/15/20 was reported as The Mystery of The Platypus Deepens With The Discovery of Its Biofluorescent Fur 10/31/20 If nothing else, the discovery is a nice reminder of our sheer ignorance. See: Epigenetics – From Bench to Clinic starts today, 11/3/20 Live Sessions include information on: RNA modifications and epitranscriptomics​​11/3/20 Polycomb and chromatin remodeling 11/9/02 DNA-dependent epigenetic events​​​ 11/16/20 Histone-mediated epigenetics​​​ 11/18/20 The facts may…

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Protonated RNA interference vs stupid theories (5)

November 3, 2020
James Kohl
Adaptations, Alternative Splicings, Cytosis, Diseases & Disorders, Ecology, RNA interference, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity
No Comments

See first: Protonated RNA interference vs stupid theories (4) See with my emphasis The noncoding and coding transcriptional landscape of the peripheral immune response in patients with COVID‐19 10/11/20 Noncoding RNAs (ncRNAs) are a class of RNAs not involved in protein production and can be subdivided into small (miRNAs, tRNAs, PIWI‐targeting RNAs) and long ncRNAs (lncRNAs), based upon their size.8 This class of RNAs not only regulates fundamental biological processes including immune system development and regulation, but also plays a…

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Protonated RNA interference vs stupid theories (4)

November 2, 2020
James Kohl
Adaptations, base editing, biophotonics, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, RNA Directed, RNA interference, Subatomic
One Comment

Remember, a vote for Joe Biden, and/or other Democrats, is a vote for more unnecessary suffering and premature deaths. See first: Protonated RNA interference vs stupid theories (3) See also: The first report on circulating microRNAs at Pre- and Post-metamorphic stages of axolotls 10/22/20 Comparison with previous reports on axolotl miRNAs unraveled common and unique members of the axolotl circulating miRNome. Overall, this work provides novel insights into non-mammalian aspects of circulating miRNA biology and expands the multi-omics toolkit for…

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Protonated RNA interference vs stupid theories (3)

November 2, 2020
James Kohl
Adaptations, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Model Organisms, Physics, RNA Directed, RNA interference, RNA-mediated epigenetic regulation of gene expression, Subatomic
One Comment

See first: Protonated RNA interference vs stupid theories (2) Summary with hashtags that link my claims from microRNA.pro to autophagy.pro via RNA-mediated.com: Qi Zhang’s group linked God’s Creation of hydrogen and #helioribogenetics from the patent for naturally occurring light-activated #protonated RNA interference to the end of all virus-driven pathology on 10/26/20 Effective cancer treatment with #proton beam therapy is proof that virtually all claims made by theorists have been used in the #gaslighting of the scientifically illiterate mask-wearing masses who…

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Protonated RNA interference vs stupid theories (2)

October 29, 2020
James Kohl
Adaptations, Alternative Splicings, base editing, biophotonics, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Subatomic
One Comment

Protonated RNA interference vs stupid theories (1) Evidence for Hidden Involvement of N3-Protonated Guanine in RNA Structure and Function 1/31/19 Charged nucleobases have been found to occur in several known RNA molecules and are considered essential for their structure and function. Estimating Strengths of Individual Hydrogen Bonds in RNA Base Pairs: Toward a Consensus between Different Computational Approaches 4/30/19 Noncoding RNA molecules are composed of a large variety of noncanonical base pairs that shape up their functionally competent folded structures.…

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Protonated RNA interference vs stupid theories (1)

October 28, 2020
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, Physics, RNA interference, Subatomic, Variations
One Comment

Visualizing a protonated RNA state that modulates microRNA-21 maturation 10/26/20 …microRNA maturation efficiency may be encoded in the intrinsic dynamic ensemble of primary and precursor microRNAs, providing a potential means of regulating microRNA biogenesis in response to environmental and cellular stimuli. See for comparison:  The landscape of host genetic factors involved in immune response to common viral infections 10/27/20 Humans and viruses have co-evolved for millennia resulting in a complex host genetic architecture. Understanding the genetic mechanisms of immune response…

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microRNA-mediated quantum error correction (4)

October 27, 2020
James Kohl
Adaptations, Alternative Splicings, biophotonics, Diseases & Disorders, Ecology, Light Energy, Physics, RNA Directed, RNA interference
One Comment

I’ve posted presentation abstract submissions here because I anticipated they would not be selected for presentation. See: UV light, H2O, and epigenetic effects… (1) 9/25/20 Submitted by James V. Kohl on 9/25/20 for presentation during the Epigenetics – From Bench to Clinic session: RNA modifications and epitranscriptomics​​ Moderator Tony Kouzarides Conclusion: Theorists who ignore the role of nutrition in biophysically constrained viral latency are largely to blame for all extant diseases. 21 See for instance: The Secret Language of Cells:…

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