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Welcome to RNA-Mediated

A Message From J.V.Kohl:

Here you will find information that links physics, chemistry, and molecular epigenetics via RNA-mediated events such as the de novo creation of olfactory receptor genes in order to encourage a public discussion of a paradigm shift.

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Biologically uninformed science idiot: Self-defense (2)

June 2, 2018
James Kohl
Adaptations, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA–Mediated Epigenetic Heredity, Subatomic
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Summary: “Construction of automata” is the operative phrase. But you must be willing to believe that the automata create themselves outside the context of the creation of sunlight and light-activated endogenous substrates in all cell types of all living genera. Causation, constructors and codes A formal definition of codes in general, and organic codes in particular, allows the relational diagram to be extended so as to capture this translation of formal cause into process. The extended relational diagram is used…

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http://www.sciencedirect.com/science/article/pii/S0303264717302782 open access

Biologically uninformed science idiot: Self-defense (1)

June 1, 2018
James Kohl
Adaptations, Diseases & Disorders, Ecology, Model Organisms, Nutrigenomics, Physics, RNA Directed, Subatomic
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I recently published a review of nutritional epigenetics. It was an invited review that was returned in 2014 without review so I placed it on a preprint server as: Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems In the past 4 years, others have linked the creation of subatomic particles from quantum physics to classical physics. Now, the slight change in the title makes more sense.  See: Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems The review already is forcing biologically…

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The eternal significance of microRNAs and the Vietnam Memorial (2)

June 1, 2018
James Kohl
Adaptations, Alternative Splicings, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Physics, RNA Directed, RNA interference, Subatomic
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Summary: Quantized energy as information has been linked from what organisms eat to biophysically constrained membrane protein construction in the context of viral latency and healthy longevity. Cryoelectron microscopy (aka electron cryomicroscopy for obfuscation) clearly links what is known about the virus-driven degradation of messenger RNA to all pathology or from energy-dependent RNA-mediated DNA repair to species survival. Membrane Proteins – Richard Henderson May 31, 2018 Energy as information and biophysically constrained membrane protein construction – James Kohl Feb 15,…

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The eternal significance of microRNAs and the Vietnam Memorial (1)

May 31, 2018
James Kohl
Adaptations, Cytosis, Diseases & Disorders, Ecology, microRNA editing, Model Organisms, Nutrigenomics, RNA Directed, RNA–Mediated Epigenetic Heredity
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Researchers who believe in the mutation-driven evolution of species and mutation-driven differences in human populations have invented another ridiculous hypothesis. Now, they believe in mathematical models that infer: Cultural hitchhiking and competition between patrilineal kin groups explain the post-Neolithic Y-chromosome bottleneck In human populations, changes in genetic variation are driven not only by genetic processes, but can also arise from cultural or social changes. An abrupt population bottleneck specific to human males has been inferred across several Old World (Africa,…

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From quantum physics to quantum souls (5)

May 31, 2018
James Kohl
Adaptations, biophotonics, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Nutrigenomics, Physics, RNA Directed, Subatomic, Variations
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Three recently published articles attest to the eternal significance of prior works that linked quantum physics to quantum souls via what  is known to all serious scientists about Energy as information and constrained endogenous RNA interference (February 15, 2017) See 1) Photosynthetic Energy Transfer at the Quantum/Classical Border June 2018 See also 2) Photosynthetic artificial organelles sustain and control ATP-dependent reactions in a protocellular system May 28, 2018 Switchable photosynthetic organelles may enable the development of biomimetic vesicle systems with regulatory…

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Cracks in The Granite Wall (2)

May 31, 2018
James Kohl
Light Energy, Physics, RNA-directed DNA methylation, RNA–Mediated Epigenetic Heredity, Subatomic, What's in the News
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Photosynthetic Energy Transfer at the Quantum/Classical Border Volume 23, Issue 6, p497–506, June 2018 links God’s creation of the sun’s anti-entropic virucidal energy to RNA-mediated DNA repair. The link from quantized energy to DNA repair was established during the same time the local news paper in Ellijay, Georgia promoted the eternal significance of the traveling Vietnam Veterans Memorial. Few people will grasp the details that link photosynthesis to carbon fixation and all biodiversity via God’s creation of sunlight and the…

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Complexity: Routes and Patterns (5)

May 31, 2018
James Kohl
Adaptations, Diseases & Disorders, Ecology, Light Energy, Physics, RNA Directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity
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Summary: Complexity does not emerge.Top-down causation is energy-dependent. Geoge FR Ellis, who co-authored The Large Scale Structure of Space-Time (1973) with physicist Stephen Hawking, just refuted every aspect of neo-Darwinian pseudoscientific nonsense and Big Bang cosmology by linking the creation of the sun’s anti-entropic virucidal energy to the complex metabolic regulatory networks of cellular function. Bacterial self-organization: co-enhancement of complexification and adaptability in a dynamic environment (2003) Learning from Bacteria about Natural Information Processing (2009) Focusing on the energy, matter,…

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From quantum physics to quantum souls (4)

May 30, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations
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The long-range consequences of food energy-dependent social factors predictably link everything known about social odors called pheromones from the quantized energy in food to metabolism and biophysically constrained viral latency.  Sympatric speciation exemplifies what is known about how quantized energy links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency in species from microbes to humans. In this review of biophysically constrained viral latency and biodiversity, I linked energy-dependent changes from angstroms to ecosystems in the mouse-to-human model of microRNA-mediated amino…

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From quantum physics to quantum souls (3)

May 29, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic
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Conclusion: The quantized energy-dependent creation of microRNAs links the anti-entropic virucidal energy of sunlight to food energy-dependent pheromone-controlled differences in all morphological and behavioral diversity via sympatric speciation. Food odors and pheromones biophysically constrain viral latency. VoteVets.org …a VoteVets.org spokesman told The Washington Post that the group had 20,000 members, including 1,000 veterans of the wars in Iraq and Afghanistan’.[6] According to the group’s website, the group has over 220,000 supporters.[7] See for comparison: Veterans Group Blasts Trump’s Memorial Day…

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From quantum physics to quantum souls (2)

May 29, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, Cytosis, Diseases & Disorders, Ecology, RNA Directed
No Comments

Summary: Natural selection for food energy-dependent codon optimality links the physiology of pheromone-controlled reproduction to all biodiversity on Earth via gene splicing and energy-dependent RNA-mediated fixation of amino acid substitutions. How humans and apes are different, and why it matters (2018) …the most distinctive feature of humanity is its ability to significantly alter ecosystems. That exemplifies human idiocy. The most distinctive features of humanity are biophysically constrained by what people eat and the physiology of pheromone-controlled reproduction. See: Nothing in Biology…

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