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Welcome to RNA-Mediated

A Message From J.V.Kohl:

Here you will find information that links physics, chemistry, and molecular epigenetics via RNA-mediated events such as the de novo creation of olfactory receptor genes in order to encourage a public discussion of a paradigm shift.

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Impeaching the God of Abraham (8)

February 28, 2021
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, microRNA editing, Model Organisms, Physics, RNA Directed, RNA editing, RNA interference, Variations
No Comments

2/22/21 In Case You Missed it. The cure for HIV and all other virus-driven pathology was announced today via an indexed publication found through my daily PubMed search for microRNA. Efficacy, accumulation, and transcriptional profile of anti-HIV shRNAs expressed from human U6, 7SK, and H1 promoters 12/31/20 & indexed on 2/22/21 announced “…a functional cure for HIV.” “The RNA polymerase III promoters H1, 7SK, and U6…” were linked to the cure or the effective treatment of all virus-driven diseases via…

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Impeaching the God of Abraham (10)

February 26, 2021
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, Physics, RNA Directed, RNA interference, RNA–Mediated Epigenetic Heredity
No Comments

sunlight and humidity can weaken the coronavirus — Donald J. Trump 4/23/20 …there’s no medical basis for Trump’s statements about sunlight.  Jonathan Reiner, professor of medicine at The George Washington University Hospital 4/24/20 Former president Trump was absolutely correct. He linked physics and chemistry to molecular biology and healthy longevity via Haplotype-resolved diverse human genomes and integrated analysis of structural variation 2/25/21 Structural variants (SVs) —inversions, deletions, duplications, and insertions ≥50 bp in length—and their breakpoints “…are generally more depleted…

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Impeaching the God of Abraham (7)

February 26, 2021
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, Cytosis, Diseases & Disorders, Ecology, microRNA editing, RNA Directed, RNA interference, RNA–Mediated Epigenetic Heredity
One Comment

MicroRNA biogenesis and their functions in regulating stem cell potency and differentiation 3/9/16 …summarizes the basic biogenesis and mode of actions of miRNAs, recent progress and discoveries of miRNAs in cellular reprogramming, stem cell differentiation and cellular communication, as well as miRNAs in CSCs. MicroRNAs organize intrinsic variation into stem cell states 3/5/20 was linked to prevention of  the virus-driven degradation of messenger RNA in CSCs via the fact that “…naturally arising cell-to-cell variation, sometimes described as stochastic fluctuation, is…

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Impeaching the God of Abraham (6)

February 26, 2021
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, RNA Directed
No Comments

I repeat: “The epigenetic effects of olfactory/pheromonal input calibrate and standardize molecular mechanisms for genetically predisposed receptor-mediated changes in intracellular signaling and stochastic gene expression…” Catalytic Asymmetric Synthesis of the anti‐COVID‐19 Drug Remdesivir 9/1/20 The catalytic asymmetric synthesis of the anti-COVID-19 drug Remdesivir… showed that this DyKAT is a first-order visual kinetic reaction dependent on the catalyst concentration. The unique chiral bicyclic imidazole skeleton and carbamate substituent of the catalyst are both required for the racemization process… The racemization process…

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Impeaching the God of Abraham (5)

February 23, 2021
James Kohl
Adaptations, Alternative Splicings, base editing, Ecology, Light Energy, microRNA editing, Model Organisms, Physics, RNA Directed, RNA editing, RNA interference, RNA–Mediated Epigenetic Heredity
No Comments

More than 116,000 indexed published works link sunlight from microRNA biogenesis to biophysically constrained viral latency across kingdoms via the energy-dependent assembly of the microRNA-RNA-peptide nanocomplex. But see: Experts say there’s no medical basis for Trump’s suggestion that sunlight, disinfectants may treat coronavirus 4/24/21 Jonathan Reiner, professor of medicine at The George Washington University Hospital, said there’s no medical basis for Trump’s statements about sunlight. See for comparison: Specific enzymatic amplification of DNA in vitro: the polymerase chain reaction (1986)…

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Impeaching the God of Abraham (4)

February 22, 2021
James Kohl
Adaptations, Alternative Splicings, biophotonics, Diseases & Disorders, Ecology, Light Energy, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA–Mediated Epigenetic Heredity, Subatomic
No Comments

Apple Peel and Flesh Contain Pro-neurogenic Compounds 2/11/21 …mammals evolved with exposure to particular diets… How could theorists continue to miss the obvious connection from light-activated plant growth to food energy, microRNA-mediated viral latency, and healthy longevity? See: MicroRNAs organize intrinsic variation into stem cell states 3/5/20 …naturally arising cell-to-cell variation, sometimes described as stochastic fluctuation, is in fact coherently organized biology. See also: Feedback loops link odor and pheromone signaling with reproduction 11/18/05 Indications that GnRH peptide plays an…

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Impeaching the God of Abraham (3)

February 15, 2021
James Kohl
Cytosis, Diseases & Disorders, Ecology, RNA Directed, RNA interference, What's in the News
No Comments

The higher the proportion of people with immunity, either through vaccination or infection, the stronger the selective pressure on the coronavirus to mutate in ways that can evade our immunity. — Dr. Tom Frieden (@DrTomFrieden) February 15, 2021 Neo-Darwinian theorists, conspiracy theorists, and Big Bang cosmologists have something in common with Communists, atheists, and researchers from Harvard who have obfuscated facts about naturally occurring energy-dependent protonated RNA interference. See: Regulation of host and virus genes by neuronal miR-138 favours herpes simplex…

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Impeaching the God of Abraham (2)

February 12, 2021
James Kohl
Adaptations, base editing, biophotonics, Diseases & Disorders, Ecology, microRNA editing, Model Organisms, Physics, RNA Directed, RNA interference, RNA-mediated epigenetic regulation of gene expression, What's in the News
One Comment

Origins of modern human ancestry 2/10/21 …no specific point in time can currently be identified at which modern human ancestry was confined to a limited birthplace… This was reported as: On the origin of our species “…neither the genetic or fossil record have so far revealed a defined time and place for the origin of our species.” See for comparison: Environmental selection during the last ice age on the mother-to-infant transmission of vitamin D and fatty acids through breast milk…

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Impeaching the God of Abraham (1)

February 11, 2021
James Kohl
Adaptations, Alternative Splicings, base editing, biophotonics, Diseases & Disorders, Ecology, microRNA editing, Model Organisms, Physics, RNA Directed, RNA interference, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, What's in the News
No Comments

2/10/21 Researchers who share the Abrahamic faiths have refuted the pseudoscientific nonsense touted by all atheists. See: microRNA 115, 376 results There are currently 1052 results for microRNA and Israel 2,063 results for microRNA and Iran 2414 results for microRNA and Korea For a historical perspective on what is known to all intelligent serious scientists about biophysically constrained viral latency across kingdoms see the references from: Regulation of host and virus genes by neuronal miR-138 favours herpes simplex virus 1…

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Life or death facts about theories (4)

February 5, 2021
James Kohl
Adaptations, biophotonics, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Physics, RNA interference, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Subatomic
No Comments

If something about the Biden administration smells ‘fishy’ to you it may be due to the fact that Evolutionists Cannot Account for the Origin of the Sense of Smell “Professor of Biology John T. Caprio of Louisiana State University states that initially, the sense of smell developed in order to identify amino acid-like chemical substances soluble in water. The ability to determine molecules floating in the air is an adaptation of that original mechanism.96” (p. 108) Here’s the link to…

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