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Welcome to RNA-Mediated

A Message From J.V.Kohl:

Here you will find information that links physics, chemistry, and molecular epigenetics via RNA-mediated events such as the de novo creation of olfactory receptor genes in order to encourage a public discussion of a paradigm shift.

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RNA-mediated silencing (7)

On 3/24/22 Reversing the miRNA -5p/-3p stoichiometry reveals physiological roles and targets of miR-140 miRNAs linked quantum coherence to coherently organized biology and quantum souls via a change in the first nucleotide in miR-140. The energy-dependent change in the first nucleotide linked Footprints of a Singular 22-Nucleotide RNA Ring at the Origin of Life (4/25/20) to Functions and underlying mechanisms of miR-650 in human cancers and Identifying the oncogenic potential of gene fusions exploiting miRNAs 3/24/22 Three of the 4…

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RNA-mediated silencing (6)

See first RNA-mediated silencing (5) The AVONET database contains 11 morphological traits, such as beak shape and wing length, for 90,020 individual birds from 181 countries. It fails to link differences in uni-parental or bi-parental feeding from fixation of amino acid substitutions to the color of white-throated sparrows, which was linked to ethnic difference in skin color via chromosomal rearrangements across kingdoms via Estrogen receptor α polymorphism in a species with alternative behavioral phenotypes  1/13/14 The failure to link food…

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RNA-mediated silencing (5)

See: RNA-mediated silencing (4)  Photostimulation provides an alternative to medication Those who promote the pharmacidal agenda, the racism agenda, and the LGBTQ-pedophile agenda have two things in common. 1) They refuse to link God’s Creation of energy as information from His Creation of sunlight and humidity to pH-dependent biophysically constrained viral latency across kingdoms via the physiology of reproduction and Biblical Genesis. 2) Until the APA apology for racism on 10/29/21, no other pseudoscientists ever apologized for their overwhelming ignorance of…

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RNA-mediated silencing (4)

Angel Trumpets are extinct in the wild. Daffodils are extremely well adapted. Other organisms and people who are not ecologically adapted suffer unnecessarily and die prematurely from the virus-driven degradation of mRNA. They do not evolve into different species. See first: RNA-mediated silencing (3) Robert H. Singer, co-authored: Single-molecule imaging of microRNA-mediated gene silencing in cells 3/17/22 Simultaneous visualization of single mRNAs, translation, and miRNA-binding revealed that miRNAs preferentially bind to translated mRNAs rather than untranslated mRNAs. Among other positions,…

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RNA-mediated silencing (3)

Robert H. Singer, co-authored: Single-molecule imaging of microRNA-mediated gene silencing in cells 3/17/22 Simultaneous visualization of single mRNAs, translation, and miRNA-binding revealed that miRNAs preferentially bind to translated mRNAs rather than untranslated mRNAs. Trust in God, but verify the fact that Singer’s publication history links God’s Creation of anti-entropic virucidal energy to biophysically constrained microRNA-mediated protein folding chemistry and healthy longevity across kingdoms via light-activated carbon fixation in cyanobacteria, and pheromone-regulated genetic processes of preferential binding and reproduction in species…

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RNA-mediated silencing (2)

Transcriptional and post-transcriptional control of epithelial-mesenchymal plasticity: why so many regulators? 3/12/22 God’s Creation of sunlight and humidity at the origin of life ~6000 years ago links light-activated carbon fixation in cyanobacteria to microRNA-mediated protein folding chemistry and healthy longevity across kingdoms via the number of regulators. Fixation of amino acid substitutions is the link to viral endemicity. The facts are clear in: Cellulose: A Plant Cell Biology Game , a STEM toy for ages 14+, which links God’s Creation…

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RNA-mediated silencing (1)

The alphavirus 3′-nontranslated region: size heterogeneity and arrangement of repeated sequence elements 1/5/98 The 19-nt conserved sequence element directly adjacent to the poly(A) tract was found in all viruses, More than 1000 indexed publications that mention microRNAs, which are small RNAs, have been added each month during the past 6 years. That makes it almost impossible to keep up with “origin of life” Science. WHO doesn’t help. Where’s Fauci? Systemic Silencing Of An Endogenous Plant Gene By Two Classes Of…

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Photonics in Forensics (9)

Suppression and Activation of Intracellular Immune Response in Initial Severe Acute Respiratory Syndrome Coronavirus 2 Infection 11/26/21 …when intracellular immunity is suppressed, SARS-CoV-2 shows a correlation with dysregulation of metal ion homeostasis. Herein, the inhibitory activity of copper ions against SARS-CoV-2 was further validated in in vitro experiments. Ions are atoms that have a positive or negative charge because they have unequal numbers of protons and electrons. If atoms lose electrons, they become positive ions, or cations. If atoms gain…

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Photonics in Forensics (8)

Light-activated carbon fixation, the resurrection of life in pear trees, and the resurrection of life in daffodils exemplifies how God’s pH-dependent peptide synthesis at the origin of life ~6000 years ago links microRNA-mediated  protein folding chemistry to protection of all organized genomes from the virus-driven degradation of messenger RNA (mRNA). For instance, see: Integrative global co-expression analysis identifies Key MicroRNA-target gene networks as key blood biomarkers for obesity 3/10/22 They linked God’s Creation of energy-dependent transcription factor networks to computational…

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