Add your custom tagline title here.

Welcome to RNA-Mediated

A Message From J.V.Kohl:

Here you will find information that links physics, chemistry, and molecular epigenetics via RNA-mediated events such as the de novo creation of olfactory receptor genes in order to encourage a public discussion of a paradigm shift.

Please subscribe and share with your friends and colleagues.

Odor activation of ATP (1)

March 26, 2018
James Kohl
Adaptations, Diseases & Disorders, Ecology
No Comments

Serious scientists start from the levels of biological organization required to link atoms to ecosystems in all living genera. They must link what is known about quantized energy to subatomic particles. See for example slide number 6 from: Human Pheromones: Linking Neuroendocrinology and Ethology (revisited)  (2010) Subatomic particles must be the link to the creation of ATP synthase, which must link the creation of ATP to the creation of RNA. See McEwen et al., (1964) Dependence of RNA synthesis in…

Read More

Part 3: Light-controlled cell biology (revisited)

March 23, 2018
James Kohl
Adaptations, Autophagy, biophotonics, Diseases & Disorders, Ecology, Light Energy, Physics, RNA Directed, RNA interference, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Variations
No Comments

Your cells are constantly being shed and replaced—so is your body ever completely refreshed? Does anything remain of the body that existed on Jan. 1, 2017? 2007? The day you were born? (video) Out of Order: Undaunted  …as I prepared for this issue’s Special Report on Microbiomics (starting on page 19), I am stunned by what I am only starting to understand. That our individual existence as humans may only be 10 percent of what we see in the mirror—and…

Read More

Part 2: Light-controlled cell biology (revisited)

March 23, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, biophotonics, Diseases & Disorders, Ecology, RNA Directed
No Comments

Greg Bear took the lead with this approach in his novel Quantico (2006). A genetically engineered virus was used to erase the memory of a specifically targeted human population to reduce inter-ethnic conflict. [Greg Bear] …served as a consultant for NASA, the U.S. Army, the State Department, the International Food Protection Association, and Homeland Security on matters ranging from privatizing space to food safety, the frontiers of microbiology and genetics, and biological security. Greg Bear is a likely candidate for…

Read More

Light-controlled cell biology (revisited)

March 21, 2018
James Kohl
Adaptations, Autophagy, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations, What's in the News
No Comments

See Sci-Bay Scholar for citations and downloads of more than 3300 published works that link viruses to microRNAs Summary: …either the organized genomes of all cell types use the energy source, or viruses use the biophysically constrained energy of the cell types. No extant species can be used as an example of how the virus-driven theft of quantized energy can be linked from natural selection to the evolution of a new species. See also, with my emphasis: Light Offers New…

Read More

Autophagy in health and disease (1)

March 21, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, microRNA editing, Model Organisms, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
No Comments

Novel Treatment Strategies for the Nervous System: Circadian Clock Genes, Non-coding RNAs, and Forkhead Transcription Factors Each of these pathways have an intimate relationship with the programmed death pathways of autophagy and apoptosis and share a common link to the silent mating type information regulation 2 homolog 1 (Saccharomyces cerevisiae) (SIRT1) and the mechanistic target of rapamycin (mTOR). Circadian clock genes are necessary to modulate autophagy, limit cognitive loss, and prevent neuronal injury. Non-coding RNAs can control neuronal stem cell…

Read More

Nick Lane refutes theistic evolution (1)

March 16, 2018
James Kohl
Adaptations, biophotonics, Diseases & Disorders, Ecology, RNA Directed
No Comments

Neo-Darwinian theorists and others who are biologically uninformed will learn this in September (2018). Synopsis: The difference in two photons has been linked to the Proton motive force. It drives the activity of the enzyme, ATP synthase, which makes ATP. All energy-dependent biophysically constrained viral latency has since been linked from the creation of ATP synthase and the creaton of ATP to changes in the microRNA/messenger RNA balance and healthy longevity. For comparison, the virus-driven degradation of messenger RNA has…

Read More

Do not refute cherished theories

March 15, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, Cytosis, Diseases & Disorders, Ecology, Model Organisms, RNA Directed
No Comments

Synopsis: All serious scientist know that pre-mRNAs (now known as microRNAs in more than 70,000 published works) do not create themselves. For comparison, Ricki Lewis fails to mention how fertility is biophysically constrained by by the creation of the sun’s anti-entropic virucidal energy, the creation of enzymes (e.g, ATP synthase), the creation of ATP, the creation of microRNAs, and the RNA-mediated creation of hormones and receptors that link achiral glycine in position 6 of the GnRH decapeptide to all experience-dependent…

Read More

MicroRNA-activated / RNA-mediated gene expression

March 15, 2018
James Kohl
Adaptations, Autophagy, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Physics, RNA Directed, RNA editing, RNA interference, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity, Subatomic
No Comments

Summary: All patterns exist only in the context of the de novo creation of  enzymes and energy-dependent microRNAs that link light-activated endogenous substrates from what is known about particle physics to biophysically constrained viral latency in the cell biology game: Cytosis. See also: miRNA activation is an endogenous gene expression pathway Moving forward: Few people are likely to ask about the origin (i.e., the de novo creation) of energy-dependent microRNAs. Fewer still will link the creation of quantized energy as…

Read More

Death cures theorist’s Amyotrophic Lateral Sclerosis (ALS).

March 15, 2018
James Kohl
Alternative Splicings, Autophagy, Diseases & Disorders, Human Brain, Neuronal Plasticity, Physics, RNA-mediated toxicity, Variations, What's in the News
No Comments

Stephen Hawking death: Was he the smartest man in the world? The media need superheroes in science just as in every sphere of life, but there is really a continuous range of abilities with no clear dividing line. For comparison: Focus on the Role of D-serine and D-amino Acid Oxidase in Amyotrophic Lateral Sclerosis/Motor Neuron Disease (ALS) A pathogenic mutation in D-amino acid oxidase (DAO) associated with familial ALS impairs D-serine metabolism and causes protein aggregation, autophagy and cell death…

Read More

Polymaths and paradigm shifts: From Asimov to Bear (5)

March 14, 2018
James Kohl
Adaptations, Alternative Splicings, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA editing, RNA interference, RNA-directed DNA methylation, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Subatomic, What's in the News
No Comments

Summary: Neil deGrasse Tyson and Lawrence Krauss are among those who have continued to substitute pseudoscientific nonsense for legitimate facts, which is what Hawking did in every book he ever wrote, and each time he made a spurious claim based on his abilities as a conniving theorist whose works still have not been confirmed-and-validated. Now that he is gone, others may proclaim the greatness of his intellect and lionize the magnitude of his influence because they also are biologically uninformed…

Read More
RSS Pheromones.com
  • What Darwin proved: there’s no such thing as a species
    GENETICS As Animals Mingle, a Baffling Genetic Barrier A short stretch of DNA is challenging what it means to be a species. By: Emily Singer August 5, 2014 Excerpt: “Scientists have dubbed such regions of the genome “islands of speciation.” The persistence of such islands is a phenomenon that has been observed in a variety of […]
RSS Perfuming the Mind
  • Randomness and Divine Providence
    A Q&A on randomness and God’s providence …the main goal is to really put together a collection of scholarly studies of these issues: physicists, biologists, […]
error: Content is protected !!