RNA-Mediated

Adaptations, Diseases & Disorders, Ecology, RNA Directed

Saying Goodbye to the RNA World Theory RNA has a limited ability for catalysis compared to peptides, and would have struggled to maintain its catalytic activity under the changing temperature conditions of early Earth. Carter and Wills also argued that if an RNA world existed, it would have been unlikely for it to incorporate peptides later on. See for comparison: Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation” (1964)…

Polymaths and paradigm shifts: from Asimov to Bear (3)

March 14, 2018

Adaptations, Alternative Splicings, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Physics, RNA Directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity

Polymaths and paradigm shifts: from Asimov to Bear (2) “Teilhardism And The New Religion: A Thorough Analysis of the Teachings of Pierre Teilhard de Chardin”, p.18, TAN Books The evolutionist thesis has become more stringently unthinkable than ever before. — Dr. Wolfgang Smith (2015). A Chat with Information Scientist Pedro Marijuán (2017) I’ve based my informational scheme of the cell on this thinking of “distinction on the adjacent” — where molecular recognition is the essential phenomenon over which biological complexity…

Polymaths and paradigm shifts: from Asimov to Bear (2)

March 14, 2018

Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, What's in the News

Polymaths and paradigm shifts: from Asimov to Bear (1) See also: Search results for virus-driven energy theft Summary: The creation of enzymes, such as ATP synthase is energy-dependent. The energy biophysically constrains viral latency via the creation of microRNAs and RNA-mediated amino acid substitutions that differentiate the cell types of all living genera. Modifying Other’s Originality without Quote is an Act of Piracy A writer who does not cite the sources in h/h feature article is committing piracy. Piracy is…

Polymaths and paradigm shifts: from Asimov to Bear (1)

March 14, 2018

Adaptations, biophotonics, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Physics, RNA Directed, RNA–Mediated Epigenetic Heredity, Subatomic, Variations

Summary: In the context of what is known about how top-down causation must be linked to all biodiversity on Earth, the anti-entropic virucidal energy of sunlight links differences in the energy of two photons from the proton motive force to the creation of microRNAs. The link from the proton motive force to the creation of microRNAs is endogenous RNA interference (RNAi). Endogenous RNAi is manifested as energy-dependent differences in biophysically constrained viral latency. Biophysically constrained viral latency has been linked…

How to create biologically uninformed theorists

March 13, 2018

Adaptations, Autophagy, biophotonics, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA interference, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Subatomic

Summary: On March 2, 2018, Philip C. Ball and Nick Lane started making claims about proton gradients. Their claims are based on my model of quantized energy as information. This post includes added support for what is known to all serious scientists about the light-activated endogenous substrates that link molecular epigenetics to RNA-mediated autophagy. See first: Energy as information and constrained endogenous RNA interference (audio/visual aid 2017) Feedback loops link quantized energy as information to biophysically constrained RNA-mediated protein folding…

Virus-mediated archaeal hecatomb in the deep seafloor

Carl Zimmer refutes theistic evolution (2)

March 11, 2018

Adaptations, Alternative Splicings, Diseases & Disorders, Ecology, RNA Directed, RNA–Mediated Epigenetic Heredity

Carl Zimmer refutes theistic evolution (1) Carl Zimmer recognizes the need for a new definition of what heredity is. But he refuses to tell others what he knows about the role that viruses play in the transgenerational epigenetic inheritance of all pathology. Examples of inherited pathology typically include his misrepresentations among others who fail to link ecological variation to ecological adaptation in the context of energy-dependent biophysically constrained viral latency. See: Ancient Viruses Are Buried in Your DNA by Carl…

Carl Zimmer refutes theistic evolution (1)

March 9, 2018

Adaptations, Alternative Splicings, Cytosis, Diseases & Disorders, Ecology, Model Organisms, RNA Directed, RNA-directed DNA methylation, RNA–Mediated Epigenetic Heredity, Variations

Primers: From photons to the proton motive force (1) and From photons to the proton motive force (2) George Church, Feng Zhang, Francis S. Collins, Stuart Kauffman, Emily Witkin, and Bill Gates are joined by Carl Zimmer. All have now refuted theistic evolution via their failed attempts to link photons from mutations to the proton motive force, or their ridiculous claims linked to the magic of evolution. Carl Zimmer may be the only so-called science journalist to have published a…

From photons to the proton motive force (2)

March 9, 2018

Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Nutrigenomics, Pharmacogenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, What's in the News

If you know someone who has linked differences in the energy of photons from the proton motive force to the physiology of reproduction and all biophysically constrained biodiversity, ask if they will attend Schrödinger at 75-The Future of Biology For contrast, touting genetic evolution is not the future of biology. See: Abstract: K06.00013 : A Path Integral Method for Analytically Tractable Inference of Evolutionary Dynamics Understanding the forces that shape genetic evolution is a subject of fundamental importance in biology…

From photons to the proton motive force (1)

March 9, 2018

Adaptations, biophotonics, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA-mediated epigenetic regulation of gene expression, Subatomic, What's in the News

Conclusion: If you would like to learn how to link quantized energy-dependent changes in atoms to ecosystems in all living genera via the physiology of reproduction, join others age 10+ who will be playing this game in September 2018. Fly’s Blood-Brain Barrier Has Circadian Rhythms “the anatomic characteristics of insect and vertebrate BBB structures are quite distinct.” The molecular mechanisms are conserved. My comment to The Scientist: Feedback of the Drosophila period gene product on circadian cycling of its messenger…

Ecological adaptation: a new definition of heredity (4)

March 9, 2018

Adaptations, Cytosis, Diseases & Disorders, Ecology, Model Organisms, Nutrigenomics, RNA Directed, RNA interference, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity, Variations