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Welcome to RNA-Mediated

A Message From J.V.Kohl:

Here you will find information that links physics, chemistry, and molecular epigenetics via RNA-mediated events such as the de novo creation of olfactory receptor genes in order to encourage a public discussion of a paradigm shift.

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pH-dependent viral latency (1)

May 22, 2020
James Kohl
Adaptations, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, RNA Directed, RNA interference
One Comment

Four back-to-back articles in Science Magazine on May 15, 2020 attest to facts about how God’s Creation of energy-as-information was linked to all biodiversity on Earth via President Donald J. Trump’s claim about UV light and facts about light activated microRNA biogenesis, which biophysically constrains viral latency via the pH-dependent physiology of reproduction.   1) Modeling infectious disease dynamics The current pandemic has no parallel…, but the new virus is following rules common to other pathogens. The so-called “rules” are…

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The tipping point (revisited): 102K (1)

May 15, 2020
James Kohl
Adaptations, Alternative Splicings, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, RNA Directed, RNA interference, RNA-mediated gene silencing
No Comments

See first:  The tipping point (revisited): 101K (1) 4/22/20 and Vaccines do not control pandemics (1) 5/15/20 Genetic inactivation of the translin/trax microRNA-degrading enzyme phenocopies the robust adiposity induced by Translin (Tsn) deletion 5/11/20 They linked virus-driven changes in light-activated energy-dependent differences in hydrogen-atom transfer in DNA base pairs in solution from microRNA flanking sequences to the degradation of messenger RNA and all obesity-linked diseases via changes in the potential of hydrogen (pH). See: Control of pH responsive peptide self-association…

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Vaccines do not control pandemics (1)

May 15, 2020
James Kohl
Adaptations, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Model Organisms, Nutrigenomics, Pharmacogenomics, Physics, RNA interference, Subatomic
2 Comments

See: Emergence of Human G2P[4] Rotaviruses in the Post-vaccination Era in South Korea: Footprints of Multiple Interspecies Re-assortment Events 4/16/18 Compared to the G2 RotaTeq vaccine strain, 17-24 amino acid changes, specifically A87T, D96N, S213D, and S242N substitutions in G2 epitopes, were observed. Amino acid changes control pandemics. Congo: MSF Ebola vaccination begins 5/30/18 The Ebola vaccine (rVSVDG-ZEBOV-GP) is being used as part of the overall strategy to control the Ebola outbreak. There was no indication that the vaccine strategy…

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The microRNA-mediated future of humanity (8)

May 8, 2020
James Kohl
Adaptations, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Model Organisms, Nutrigenomics, Pharmacogenomics, Physics, RNA Directed, RNA interference, Subatomic, Variations
No Comments

The levels of complexity linked to the microRNA-mediated future of humanity can be examined by ages 10-14+ via game-play of: Bacillus (failed project) See instead: Function of miR825 and miR825* as Negative Regulators in Bacillus cereus AR156-elicited Systemic Resistance to Botrytis cinerea in Arabidopsis thaliana 10/17/19 Peptide Players compete to link amino acids to build a peptide chain (a fancy word for a protein). Virulence Players take on the role of viruses and compete to infect a host cell in…

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The microRNA-mediated future of humanity (7)

May 6, 2020
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, RNA Directed, RNA interference
No Comments

Until recently, particle physics could not be linked to coherently organized biology by arbitrarily large energies. But KB Whaley and others have linked quantum coherence to high energy completion and President Donald J. Trump’s claims about effective coronavirus treatment with remdesivir. See also: INDY inhibition attenuates diet-induced NASH  (March 2020) Conserved molecular mechanisms link the light-activated assembly of the microRNA-RNA-peptide nanocomplex from the plasma-membrane tricarboxylate transporter INDY (I’m Not Dead Yet) to effective treatment of coronavirus pathology with remdesivir. If…

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The microRNA-mediated future of humanity (5)

May 1, 2020
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, Physics, RNA Directed, RNA interference, Subatomic, Variations
No Comments

Coronavirus facts from Scientific Creationists in South Korea (reported as a coronavirus tip to Business Insider on 5/1/2020) Re: “South Korea says recovered coronavirus patients who tested positive again did not relapse: Tests picked up ‘dead virus fragments’ Summary: Scientists from the so-called “Creationist Capital of the World” linked inaccurate test results to the end of the ongoing well-orchestrated coronavirus crisis. They also linked President Trump’s claims about UV light-activated microRNA biogenesis to protection from stress-linked virus-driven pathology in all…

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The microRNA-mediated future of humanity (3)

April 24, 2020
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, Nutrigenomics, Pharmacogenomics, Physics, RNA interference, What's in the News
No Comments

Light-activated microRNA biogenesis has been linked from the pheromone-controlled physiology of reproduction to healthy longevity via protection from the virus-driven degradation of messenger RNA in all living genera. On 4/21/20 that fact was misrepresented as: Coronavirus has mutated into at least 30 different strains, Chinese study finds. The report was based on this non-peer-reviewed paper Patient-derived mutations impact pathogenicity of SARS-CoV-2 We observed intrapersonal variation and 6 different mutations in the spike glycoprotein (S protein), including 2 different SNVs that…

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The tipping point (revisited): 100K (4)

April 7, 2020
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Nutrigenomics, RNA Directed, RNA interference
No Comments

The wisdom gap The resulting “wisdom gap” leaves us ripe for manipulation… unaware of threats and unprepared for dangers. And as science and technology push the bounds of the possible, the “wisdom gap” will render us increasingly unable to wrestle with how far those bounds should be pushed. Wrestle with this: Why is Oregon still on lock down? Many people want to believe our health authorities know what they’re doing. Intelligent serious scientists know that our health authorities are corrupt.…

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FDA’s ignorance: From roots to shoots (2)

April 6, 2020
James Kohl
Adaptations, Diseases & Disorders, Ecology, Model Organisms, RNA interference
No Comments

Quantum coherence is linked to coherently organized biology in a well-ordered Universe, which is what happened in two recent publications. MicroRNAs organize intrinsic variation into stem cell states 3/5/20 MicroRNA Involvement in Signaling Pathways During Viral Infection 3/10/20 See also: FDA’s ignorance: From roots to shoots (1) 3/9/20 ‘Everything depends on where you got virus’: US & Russian top specialists explain odds of catching Covid-19 & surviving 3/8/20  “We are aware of at least 40 coronaviruses” One amino acid substitution…

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NIAID’s ignorance: from roots to shoots (1)

April 5, 2020
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, Cytosis, Diseases & Disorders, Ecology, Model Organisms, RNA Directed, RNA interference
No Comments

At the National Institute of Allergy and Infectious Diseases (NIAID), a biologically uninformed science idiot and vax-pusher named Anthony S. Fauci is helping others like him to destroy the economy. That brought forth something akin to martial law in the State of Georgia, and other states. I’ve lived in Georgia since 2003 and have a vested interest in protecting my friends (and family) from people like Fauci. I have also been a vocal advocate for learning about how sunlight, water,…

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