2018 Chemistry Nobel Laureate, Frances H. Arnold failed to link the light-activated assembly of the microRNA-RNA-peptide nanocomplex from microRNA biogenesis to her claims about the evolution of enzymes, which were retracted.
“For my first work-related tweet of 2020, I am totally bummed to announce that we have retracted last year’s paper on enzymatic synthesis of beta-lactams. The work has not been reproducible,” she tweeted.
beta-lactamase confers penicillin resistance to various bacterial organisms by cleaving the beta-lactam ring of penicillins and cephalosporin antibiotics.
The “cleaving” is energy-dependent. Clearly, no experimental evidence suggests that the energy-dependent function of the enzyme that confers penicillin resistance somehow evolved. First, energy-as-information would have had to evolve.
See for comparison:
Light induced energy-dependent changes link angstroms to ecosystems from classical physics to chemistry/chirality and to molecular epigenetics/autophagy.
Thank God, Bernard Feringa established the facts that link God’s Creation of energy to the functional structure of supercoiled DNA before he won his 2016 Nobel Prize in Chemistry.
Here, we report that unidirectional rotary motors with connecting oligobipyridyl ligands, which can dynamically change their chirality upon irradiation, assemble into metal helicates that are responsive to light.
These findings indicate that the substitution of glycine for a chiral amino acid in GnRH during evolution allows a more constrained conformation for receptor binding and that this subtle single amino acid substitution in a site remote from the ligand functional domains has marked effects on its structure and activity.
The stability of organized genomes in all jawed vertebrates has been linked from light-activated plant growth to food energy-dependent pheromone-regulated genetic processes via achiral glycine in position 6 of the gonadotropin releasing hormone decapeptide. Nothing known to serious scientists links anything to the evolution of GnRH-directed receptor selectivity.
For comparison, femtosecond blasts of UV light have been linked to DNA repair.
See: Ultraviolet Absorption Induces Hydrogen-Atom Transfer in G⋅C Watson–Crick DNA Base Pairs in Solution 10/13/15 and UV-Induced Charge Transfer States in DNA Promote Sequence Selective Self-Repair 1/13/16
It is time to ask people like Frances H. Arnold what they were thinking when they failed to start with God’s Creation of anti-entropic virucidal energy and invented stupid theories about the evolution of enzymes that led to retractions of Nobel Prize-winning works.
See for comparison: The Future of Chemistry – Schrödinger at 75: The Future of Biology
Disabled were walking again, the blind were seeing again, and the death rose from the grave. 2013 was the year in which prophesy from the bible became reality. — De Correspondent dec 2013
If Twitter did not incorporate Political Ideology into their algorithms, there would be no explanation for the dramatic decline in the number of impressions my tweets made in January 2020 and the number they are currently making.
The change is from nearly 20,000 per day for 28 days to less than 3,000 per day from January 1 until January 18, 2021. If Twitter did not want people to recognize the facts about God’s Creation of all biophysically constrained biodiversity on Earth, they would only need to prevent most people from seeing my Tweets. Instead, they permanently suspended the account of President Donald J. Trump who linked sunlight and humidity to the weakening of coronavirus pathology and to proton beam therapy for cancer on 4/23/20.